Mesothelin Monoclonal Antibody (5B2) | Invitrogen MA5-11918 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Mesothelin Monoclonal Antibody (5B2)

catalog :

MA5-11918

quantity :

500 µL

price :

US 436

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B2

reactivity :

human

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...; fig 3f	Watanabe K, Luo Y, Da T, Guedan S, Ruella M, Scholler J, et al. Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses. JCI Insight. 2018;3: pubmed publisher
immunohistochemistry - paraffin section; human; 1:10; fig 2	Ibrahim D, Abouhashem N. Diagnostic value of IMP3 and mesothelin in differentiating pancreatic ductal adenocarcinoma from chronic pancreatitis. Pathol Res Pract. 2016;212:288-93 pubmed publisher
immunohistochemistry; human; 1:30; loading ...; fig 4b	Wang E, Wang L, Tsai C, Bhoj V, Gershenson Z, Moon E, et al. Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors. Cancer Immunol Res. 2015;3:815-26 pubmed publisher
immunohistochemistry; human; 1:100	Tchou J, Wang L, Selven B, Zhang H, Conejo Garcia J, Borghaei H, et al. Mesothelin, a novel immunotherapy target for triple negative breast cancer. Breast Cancer Res Treat. 2012;133:799-804 pubmed publisher
immunohistochemistry; human; 1:20	Sasaki M, Araki I, Yasui T, Kinoshita M, Itatsu K, Nojima T, et al. Primary localized malignant biphasic mesothelioma of the liver in a patient with asbestosis. World J Gastroenterol. 2009;15:615-21 pubmed
immunohistochemistry; human	Velasco P, Huegel R, Brasch J, Schröder J, Weichenthal M, Stockfleth E, et al. The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions. J Invest Dermatol. 2009;129:2022-30 pubmed publisher
immunohistochemistry; human; 1:20	Jhala N, Jhala D, Vickers S, Eltoum I, Batra S, Manne U, et al. Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates. Am J Clin Pathol. 2006;126:572-9 pubmed
	Chang M, Chen C, Chen P, Chiang Y, Chen Y, Mao T, et al. Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways. Biochem J. 2012;442:293-302 pubmed publisher
	Sato N, Fukushima N, Maitra A, Iacobuzio Donahue C, Van Heek N, Cameron J, et al. Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas. Am J Pathol. 2004;164:903-14 pubmed

product information

Product Type :

Antibody

Product Name :

Mesothelin Monoclonal Antibody (5B2)

Catalog # :

MA5-11918

Quantity :

500 µL

Price :

US 436

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:5-1:10

Species :

Human

Clone :

5B2

Isotype :

IgG1

Storage :

4° C

Description :

Mesothelin is a GPI-linked cell-surface glycoprotein, that is present on the surface of normal mesothelium and is overexpressed in many patients with epithelial ovarian cancer and malignant mesotheliomas.

Immunogen :

Recombinant protein corresponding to the membrane-bound form of the mesothelin molecule

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:5-1:10

Aliases :

CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; Msln; pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein