This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD105 Monoclonal Antibody (SN6h)
catalog :
MA5-11854
quantity :
500µL
price :
US 338
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SN6h
reactivity :
human, bovine, swine, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, blocking or activating experiments
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 1
Yin T, He S, Su C, Chen X, Zhang D, Wan Y, et al. Genetically modified human placenta‑derived mesenchymal stem cells with FGF‑2 and PDGF‑BB enhance neovascularization in a model of hindlimb ischemia. Mol Med Rep. 2015;12:5093-9 pubmed publisher
  • immunohistochemistry; human; 1:50
Gurzu S, Ciortea D, Tamasi A, Golea M, Bodi A, Sahlean D, et al. The immunohistochemical profile of granular cell (Abrikossoff) tumor suggests an endomesenchymal origin. Arch Dermatol Res. 2015;307:151-7 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Lytras D, Leontara V, Kefala M, Foukas P, Giannakou N, Pouliakis A, et al. Microvessel Landscape Assessment in Pancreatic Ductal Adenocarcinoma: Unclear Value of Targeting Endoglin (CD105) as Prognostic Factor of Clinical Outcome. Pancreas. 2015;44:87-92 pubmed publisher
  • immunocytochemistry; human
Yuan S, Guo Y, Zhou X, Shen W, Chen H. PDGFR-? (+) perivascular cells from infantile hemangioma display the features of mesenchymal stem cells and show stronger adipogenic potential in vitro and in vivo. Int J Clin Exp Pathol. 2014;7:2861-70 pubmed
  • immunohistochemistry - paraffin section; domestic rabbit; 1:75
Wen Q, Zhou C, Luo W, Zhou M, Ma L. Pro-osteogenic effects of fibrin glue in treatment of avascular necrosis of the femoral head in vivo by hepatocyte growth factor-transgenic mesenchymal stem cells. J Transl Med. 2014;12:114 pubmed publisher
  • immunohistochemistry; human; 1:50
Clara C, Marie S, de Almeida J, Wakamatsu A, Oba Shinjo S, Uno M, et al. Angiogenesis and expression of PDGF-C, VEGF, CD105 and HIF-1? in human glioblastoma. Neuropathology. 2014;34:343-52 pubmed publisher
  • immunohistochemistry; human
Akdur N, Donmez M, Gözel S, Ustun H, Hucumenoglu S. Intravascular papillary endothelial hyperplasia: histomorphological and immunohistochemical features. Diagn Pathol. 2013;8:167 pubmed publisher
  • immunohistochemistry; human; 1:50
Gurzu S, Ciortea D, Munteanu T, Kezdi Zaharia I, Jung I. Mesenchymal-to-endothelial transition in Kaposi sarcoma: a histogenetic hypothesis based on a case series and literature review. PLoS ONE. 2013;8:e71530 pubmed publisher
  • blocking or activating experiments; human
Nolan Stevaux O, Zhong W, Culp S, Shaffer K, Hoover J, Wickramasinghe D, et al. Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies. PLoS ONE. 2012;7:e50920 pubmed publisher
  • immunohistochemistry - paraffin section; domestic rabbit; fig 3
Wen Q, Jin D, Zhou C, Zhou M, Luo W, Ma L. HGF-transgenic MSCs can improve the effects of tissue self-repair in a rabbit model of traumatic osteonecrosis of the femoral head. PLoS ONE. 2012;7:e37503 pubmed publisher
  • immunocytochemistry; human
Yuan S, Chen R, Shen W, Chen H, Zhou X. Mesenchymal stem cells in infantile hemangioma reside in the perivascular region. Pediatr Dev Pathol. 2012;15:5-12 pubmed publisher
  • immunohistochemistry; human; 1:40
Alkhabuli J. Significance of neo-angiogenesis and immuno-surveillance cells in squamous cell carcinoma of the tongue. Libyan J Med. 2007;2:30-9 pubmed publisher
  • flow cytometry; swine
Zhang X, Xu Y, Thomas V, Bellis S, Vohra Y. Engineering an antiplatelet adhesion layer on an electrospun scaffold using porcine endothelial progenitor cells. J Biomed Mater Res A. 2011;97:145-51 pubmed publisher
  • flow cytometry; human; 1:50
Zhao J, Gao Z, Mei H, Li Y, Wang Y. Differentiation of human mesenchymal stem cells: the potential mechanism for estrogen-induced preferential osteoblast versus adipocyte differentiation. Am J Med Sci. 2011;341:460-8 pubmed publisher
  • immunohistochemistry; human; 1:50
Jung I, Gurzu S, Raica M, Cimpean A, Szentirmay Z. The differences between the endothelial area marked with CD31 and CD105 in colorectal carcinomas by computer-assisted morphometrical analysis. Rom J Morphol Embryol. 2009;50:239-43 pubmed
  • immunohistochemistry; human
Gurzu S, Jung I, Prantner I, Ember I, Pávai Z, Mezei T. The expression of cytoskeleton regulatory protein Mena in colorectal lesions. Rom J Morphol Embryol. 2008;49:345-9 pubmed
  • immunohistochemistry; human
Gurzu S, Jung J, Azamfirei L, Mezei T, Cimpean A, Szentirmay Z. The angiogenesis in colorectal carcinomas with and without lymph node metastases. Rom J Morphol Embryol. 2008;49:149-52 pubmed
  • immunohistochemistry; human
Gurzu S, Jung J, Azamfirei L, Mezei T, Cimpean A. The aspects of angiogenesis in anal canal carcinomas compared with that in colorectal carcinomas. Rom J Morphol Embryol. 2007;48:349-53 pubmed
  • western blot; human
Einspahr J, Thomas T, Saboda K, Nickolof B, Warneke J, Curiel Lewandrowski C, et al. Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression. Cancer. 2007;110:2519-27 pubmed
  • immunocytochemistry; human
Schlabe J, Johnen C, Schwartlander R, Moser V, Hartmann B, Gerlach J, et al. Isolation and culture of different epidermal and dermal cell types from human scalp suitable for the development of a therapeutical cell spray. Burns. 2008;34:376-84 pubmed
  • immunocytochemistry; human
Duret C, Gerbal Chaloin S, Ramos J, Fabre J, Jacquet E, Navarro F, et al. Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver. Stem Cells. 2007;25:1779-90 pubmed
  • immunohistochemistry; human; 0.4 mg/l
Yu J, Cui L, Zhang Q, Chen H, Ji P, Wei H, et al. Expression of NOS and HIF-1alpha in human colorectal carcinoma and implication in tumor angiogenesis. World J Gastroenterol. 2006;12:4660-4 pubmed
  • immunohistochemistry; human; 1:100
Yang L, Lu W, Huang G, Wang W. Correlation between CD105 expression and postoperative recurrence and metastasis of hepatocellular carcinoma. BMC Cancer. 2006;6:110 pubmed
  • flow cytometry; human
He X, Li Y, Wang X, Guo X, Niu Y. [Mesenchymal stem cells transduced by PLEGFP-N1 retroviral vector maintain their biological features and differentiation]. Chin Med J (Engl). 2005;118:1728-34 pubmed
Wurmser A, Nakashima K, Summers R, Toni N, D Amour K, Lie D, et al. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature. 2004;430:350-6 pubmed
product information
Product Type :
Antibody
Product Name :
CD105 Monoclonal Antibody (SN6h)
Catalog # :
MA5-11854
Quantity :
500µL
Price :
US 338
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Bovine, Human
Applications :
Flow Cytometry: 0.5-1 µg/test, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100 - 200, Western Blot: 1-2 µg/mL
Species :
Bovine, Human
Clone :
SN6h
Isotype :
IgG1, kappa
Storage :
4° C
Description :
CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-Beta1 and Beta3 with high affinity but not TGF-Beta2.
Immunogen :
Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5-1 µg/test, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Paraffin): 1:100 - 200, Western Blot: 1-2 µg/mL
Aliases :
CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA