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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD24 Monoclonal Antibody (SN3)
catalog :
MA5-11828
quantity :
500 uL
price :
US 429.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SN3
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 39
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig s3
Chen Y, Lu C, Cheng W, Kuo K, Yu C, Ho H, et al. An experimental model for ovarian cancer: propagation of ovarian cancer initiating cells and generation of ovarian cancer organoids. BMC Cancer. 2022;22:967 pubmed publisher
Mazar J, Brooks J, Peloquin M, Rosario R, Sutton E, Longo M, et al. The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner. Cancer Res Commun. 2024;4:65-80 pubmed publisher
Esquer H, Zhou Q, Abraham A, Labarbera D. Advanced High-Content-Screening Applications of Clonogenicity in Cancer. SLAS Discov. 2020;25:734-743 pubmed publisher
Wu A, Yu B, Zhang K, Xu Z, Wu D, He J, et al. Transmissible gastroenteritis virus targets Paneth cells to inhibit the self-renewal and differentiation of Lgr5 intestinal stem cells via Notch signaling. Cell Death Dis. 2020;11:40 pubmed publisher
Shirasu N, Shibaguchi H, Yamada H, Kuroki M, Yasunaga S. Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies. Cancer Cell Int. 2019;19:299 pubmed publisher
Mazar J, Li Y, Rosado A, Phelan P, Kedarinath K, Parks G, et al. Zika virus as an oncolytic treatment of human neuroblastoma cells requires CD24. PLoS ONE. 2018;13:e0200358 pubmed publisher
Deshmukh A, Kumar S, Arfuso F, Newsholme P, Dharmarajan A. Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines. Sci Rep. 2017;7:2256 pubmed publisher
Hu J, Li G, Zhang P, Zhuang X, Hu G. A CD44v+ subpopulation of breast cancer stem-like cells with enhanced lung metastasis capacity. Cell Death Dis. 2017;8:e2679 pubmed publisher
Zhao H, Tang H, Xiao Q, He M, Zhao L, Fu Y, et al. The Hedgehog signaling pathway is associated with poor prognosis in breast cancer patients with the CD44+/CD24? phenotype. Mol Med Rep. 2016;14:5261-5270 pubmed publisher
Keefer M, Zheng B, Rosenberg A, Kobie J. Increased Steady-State Memory B Cell Subsets Among High-Risk Participants in an HIV Vaccine Trial. AIDS Res Hum Retroviruses. 2016;32:1143-1148 pubmed
Piepenbrink M, Samuel M, Zheng B, Carter B, Fucile C, Bunce C, et al. Humoral Dysregulation Associated with Increased Systemic Inflammation among Injection Heroin Users. PLoS ONE. 2016;11:e0158641 pubmed publisher
Modur V, Joshi P, Nie D, Robbins K, Khan A, Rao K. CD24 Expression May Play a Role as a Predictive Indicator and a Modulator of Cisplatin Treatment Response in Head and Neck Squamous Cellular Carcinoma. PLoS ONE. 2016;11:e0156651 pubmed publisher
Labani Motlagh A, Israelsson P, Ottander U, Lundin E, Nagaev I, Nagaeva O, et al. Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity. Tumour Biol. 2016;37:5455-66 pubmed publisher
Kwon M, Han J, Seo J, Song K, Jeong H, Choi J, et al. CD24 Overexpression Is Associated with Poor Prognosis in Luminal A and Triple-Negative Breast Cancer. PLoS ONE. 2015;10:e0139112 pubmed publisher
KapucuoÄŸlu N, Bozkurt K, BaÅŸpınar Å, Koçer M, EroÄŸlu H, Akdeniz R, et al. The clinicopathological and prognostic significance of CD24, CD44, CD133, ALDH1 expressions in invasive ductal carcinoma of the breast: CD44/CD24 expression in breast cancer. Pathol Res Pract. 2015;211:740-7 pubmed publisher
Karakas D, Cevatemre B, Aztopal N, Ari F, Yilmaz V, Ulukaya E. Addition of niclosamide to palladium(II) saccharinate complex of terpyridine results in enhanced cytotoxic activity inducing apoptosis on cancer stem cells of breast cancer. Bioorg Med Chem. 2015;23:5580-6 pubmed publisher
Tipton C, Fucile C, DARCE J, Chida A, Ichikawa T, Gregoretti I, et al. Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. Nat Immunol. 2015;16:755-65 pubmed publisher
Rito M, Schmitt F, Pinto A, André S. Fibromatosis-like metaplastic carcinoma of the breast has a claudin-low immunohistochemical phenotype. Virchows Arch. 2014;465:185-91 pubmed publisher
Ghebeh H, Sleiman G, Manogaran P, Al Mazrou A, Barhoush E, Al Mohanna F, et al. Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers. BMC Cancer. 2013;13:289 pubmed publisher
Ianez R, Coutinho Camillo C, Buim M, Pinto C, Soares F, Lourenço S. CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators?. Histopathology. 2013;62:1075-82 pubmed publisher
Corrêa N, Kuasne H, Faria J, Seixas C, Santos I, Abreu F, et al. Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors. Oncol Rep. 2013;29:1299-307 pubmed publisher
Kaminski D, Wei C, Rosenberg A, Lee F, Sanz I. Multiparameter flow cytometry and bioanalytics for B cell profiling in systemic lupus erythematosus. Methods Mol Biol. 2012;900:109-34 pubmed publisher
Deng J, Gao G, Wang L, Wang T, Yu J, Zhao Z. CD24 expression as a marker for predicting clinical outcome in human gliomas. J Biomed Biotechnol. 2012;2012:517172 pubmed publisher
Heindl M, Händel N, Ngeow J, Kionke J, Wittekind C, Kamprad M, et al. Autoimmunity, intestinal lymphoid hyperplasia, and defects in mucosal B-cell homeostasis in patients with PTEN hamartoma tumor syndrome. Gastroenterology. 2012;142:1093-1096.e6 pubmed publisher
Takehara M, Hoshino T, Namba T, Yamakawa N, Mizushima T. Acetaminophen-induced differentiation of human breast cancer stem cells and inhibition of tumor xenograft growth in mice. Biochem Pharmacol. 2011;81:1124-35 pubmed publisher
Rybak A, He L, Kapoor A, Cutz J, Tang D. Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells. Biochim Biophys Acta. 2011;1813:683-94 pubmed publisher
Kim H, Kim M, Ahn S, Son B, Kim S, Ahn J, et al. Different prognostic significance of CD24 and CD44 expression in breast cancer according to hormone receptor status. Breast. 2011;20:78-85 pubmed publisher
Yang X, Xu Y, Yu B, Zhou J, Li J, Qiu S, et al. CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery. Clin Cancer Res. 2009;15:5518-27 pubmed publisher
Tanei T, Morimoto K, Shimazu K, Kim S, Tanji Y, Taguchi T, et al. Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers. Clin Cancer Res. 2009;15:4234-41 pubmed publisher
Sano A, Kato H, Sakurai S, Sakai M, Tanaka N, Inose T, et al. CD24 expression is a novel prognostic factor in esophageal squamous cell carcinoma. Ann Surg Oncol. 2009;16:506-14 pubmed publisher
Ostroumov E, Hunter C. The role of extracellular factors in human metastatic chordoma cell growth in vitro. Spine (Phila Pa 1976). 2007;32:2957-64 pubmed
Bennett M, Czech K, Arend L, Witte D, Devarajan P, Potter S. Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli. Nephron Exp Nephrol. 2007;107:e30-40 pubmed
Wei C, Anolik J, Cappione A, Zheng B, Pugh Bernard A, Brooks J, et al. A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus. J Immunol. 2007;178:6624-33 pubmed
Fromm J, Kussick S, Wood B. Identification and purification of classical Hodgkin cells from lymph nodes by flow cytometry and flow cytometric cell sorting. Am J Clin Pathol. 2006;126:764-80 pubmed
Weichert W, Denkert C, Burkhardt M, Gansukh T, Bellach J, Altevogt P, et al. Cytoplasmic CD24 expression in colorectal cancer independently correlates with shortened patient survival. Clin Cancer Res. 2005;11:6574-81 pubmed
Su M, Hsu C, Kao H, Jeng Y. CD24 expression is a prognostic factor in intrahepatic cholangiocarcinoma. Cancer Lett. 2006;235:34-9 pubmed
Meinhold Heerlein I, Bauerschlag D, Hilpert F, Dimitrov P, Sapinoso L, Orlowska Volk M, et al. Molecular and prognostic distinction between serous ovarian carcinomas of varying grade and malignant potential. Oncogene. 2005;24:1053-65 pubmed
Kristiansen G, Pilarsky C, Wissmann C, Kaiser S, Bruemmendorf T, Roepcke S, et al. Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival. J Pathol. 2005;205:359-76 pubmed
Kristiansen G, Pilarsky C, Pervan J, Stürzebecher B, Stephan C, Jung K, et al. CD24 expression is a significant predictor of PSA relapse and poor prognosis in low grade or organ confined prostate cancer. Prostate. 2004;58:183-92 pubmed
product information
Product Type :
Antibody
Product Name :
CD24 Monoclonal Antibody (SN3)
Catalog # :
MA5-11828
Quantity :
500 uL
Price :
US 429.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
Species :
Human, Mouse
Clone :
SN3
Isotype :
IgG1, kappa
Storage :
4 C
Description :
CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, and control of autoimmunity.
Immunogen :
Cell membrane antigen preparation isolated from NALM-1 human pre-B leukemia cell line
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: Assay-dependent
Aliases :
CD24; CD24 antigen; CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24 molecule; CD24A; CD24a antigen; cluster of differentiation 24; FLJ22950; FLJ43543; heat stable antigen; heat-stable antigen; HSA; Ly-52; Lymphocyte antigen 52; M1/69-J11D heat stable antigen; MGC75043; Nectadrin; nectadrin heat stable antigen; R13-Ag; Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen; X62 heat stable antigen
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA