CD15 Monoclonal Antibody (MMA (LeuM1)) | Invitrogen MA5-11789 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD15 Monoclonal Antibody (MMA (LeuM1))

catalog :

MA5-11789

quantity :

500 µL

price :

US 374

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MMA (LeuM1)

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human	Lorenzi L, Tabellini G, Vermi W, Moratto D, Porta F, Notarangelo L, et al. Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects. PLoS ONE. 2013;8:e80131 pubmed publisher
immunocytochemistry; human; 1:100	Buttler D, Mai J, Ashwell K, Andressen C. Clonogenic CD15 immunoreactive radial glial cells from the developing human lateral ganglionic eminence. Curr Pharm Biotechnol. 2013;14:29-35 pubmed
immunohistochemistry; human	Lorenzi L, Lonardi S, Petrilli G, Tanda F, Bella M, Laurino L, et al. Folliculocentric B-cell-rich follicular dendritic cells sarcoma: a hitherto unreported morphological variant mimicking lymphoproliferative disorders. Hum Pathol. 2012;43:209-15 pubmed publisher
immunohistochemistry; human	Maounis N, Chorti M, Legaki S, Ellina E, Emmanouilidou A, Demonakou M, et al. Metastasis to the breast from an adenocarcinoma of the lung with extensive micropapillary component: a case report and review of the literature. Diagn Pathol. 2010;5:82 pubmed publisher
immunohistochemistry - paraffin section; human; tbl 1	Leong A, Haffajee Z. Citraconic anhydride: a new antigen retrieval solution. Pathology. 2010;42:77-81 pubmed publisher
immunohistochemistry; human; 1:100	Kelten C, Kabukcu S, Sen N, Teke Z, Yaren A, Erdem E, et al. Secondary involvement of the breast in T-cell non-Hodgkin lymphoma, an unusual example mimicking inflammatory breast carcinoma. Arch Gynecol Obstet. 2009;280:149-52 pubmed publisher
immunocytochemistry; human; 1:100	Boer K, Jansen F, Nellist M, Redeker S, van den Ouweland A, Spliet W, et al. Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex. Epilepsy Res. 2008;78:7-21 pubmed
immunohistochemistry; human; 1:100	Ravizza T, Gagliardi B, Noe F, Boer K, Aronica E, Vezzani A. Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy. Neurobiol Dis. 2008;29:142-60 pubmed
immunocytochemistry; human; 1:100	Mo Z, Moore A, Filipovic R, Ogawa Y, Kazuhiro I, Antic S, et al. Human cortical neurons originate from radial glia and neuron-restricted progenitors. J Neurosci. 2007;27:4132-45 pubmed
immunohistochemistry; human	Demirag F, Unsal E, Tastepe I. Biphasic malignant mesothelioma cases with osseous differentiation and long survival: a review of the literature. Lung Cancer. 2007;57:233-6 pubmed
	Tulunay O, Gogus C, Baltaci S, Bulut S. Clear cell adenocarcinoma of the tunica vaginalis of the testis with an adjacent uterus-like tissue. Pathol Int. 2004;54:641-7 pubmed

image

image 1 :

Formalin-fixed, paraffin-embedded human Hodgkin’s lymphoma stained with CD15 antibody using peroxidase-conjugate and DAB chromogen. Note membrane staining of Reedternberg’s cells.

product information

Product Type :

Antibody

Product Name :

CD15 Monoclonal Antibody (MMA (LeuM1))

Catalog # :

MA5-11789

Quantity :

500 µL

Pricing :

US 374

Clonality :

Monoclonal

Purity :

Ammonium sulfate precipitation

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:100

Species :

Human

Clone :

MMA (LeuM1)

Isotype :

IgM, kappa

Storage :

4° C

Description :

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

Immunogen :

U937 histiocytic cell line

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1:50-1:100

more info or order :

Invitrogen product webpage