This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Tryptase Monoclonal Antibody (AA1)
catalog :
MA5-11711
quantity :
500 µL
price :
US 440
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AA1
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/Sample/DilutionReference
  • ELISA; human; tbl 1
Vyzoukaki R, Tsirakis G, Pappa C, Devetzoglou M, Tzardi M, Alexandrakis M. The Impact of Mast Cell Density on the Progression of Bone Disease in Multiple Myeloma Patients. Int Arch Allergy Immunol. 2015;168:263-8 pubmed publisher
  • immunocytochemistry; human
Ningyan G, Xu Y, Hongfei S, Jingjing C, Min C. The role of macrophage migration inhibitory factor in mast cell-stimulated fibroblast proliferation and collagen production. PLoS ONE. 2015;10:e0122482 pubmed publisher
  • immunohistochemistry; human
Blatner N, Tsai F, Khazaie K. Methods for the study of mast cells in cancer. Methods Mol Biol. 2015;1220:443-60 pubmed publisher
  • immunohistochemistry; rat
Kim Y, Lee M, Ryu H, Choi E, Oh J, Yun K, et al. Regional Differences in Chronic Stress-induced Alterations in Mast Cell and Protease-activated Receptor-2-positive Cell Numbers in the Colon of Ws/Ws Rats. J Neurogastroenterol Motil. 2014;20:54-63 pubmed publisher
  • immunohistochemistry; human; 1:1000
Birklein F, Drummond P, Li W, Schlereth T, Albrecht N, Finch P, et al. Activation of cutaneous immune responses in complex regional pain syndrome. J Pain. 2014;15:485-95 pubmed publisher
  • immunohistochemistry; human; 1:4000
Ahn J, Lee K, Choi C, Kim J, Lee H, Kim J, et al. Colonic mucosal immune activity in irritable bowel syndrome: comparison with healthy controls and patients with ulcerative colitis. Dig Dis Sci. 2014;59:1001-11 pubmed publisher
  • immunohistochemistry; human; 1:1000
Rusu M, Didilescu A, Stănescu R, Pop F, Mănoiu V, Jianu A, et al. The mandibular ridge oral mucosa model of stromal influences on the endothelial tip cells: an immunohistochemical and TEM study. Anat Rec (Hoboken). 2013;296:350-63 pubmed publisher
  • immunohistochemistry; human; 1:1000
Rupp S, Bauer J, von Gerlach S, Fichtlscherer S, Zeiher A, Dimmeler S, et al. Pressure overload leads to an increase of cardiac resident stem cells. Basic Res Cardiol. 2012;107:252 pubmed publisher
  • immunohistochemistry; human
Peterson S, Poposki J, Nagarkar D, Chustz R, Peters A, Suh L, et al. Increased expression of CC chemokine ligand 18 in patients with chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2012;129:119-27.e1-9 pubmed publisher
  • immunohistochemistry; human; 1:400
Han W, Lu X, Jia X, Zhou T, Guo C. Soluble mediators released from PI-IBS patients' colon induced alteration of mast cell: involvement of reactive oxygen species. Dig Dis Sci. 2012;57:311-9 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Keles N, Yavuz Arican R, Coskun M, Elpek G. Histamine induces the neuronal hypertrophy and increases the mast cell density in gastrointestinal tract. Exp Toxicol Pathol. 2012;64:713-6 pubmed publisher
  • immunohistochemistry; human
Trani N, Bonetti L, Gualandri G, Barbolini G. Immediate anaphylactic death following antibiotics injection: splenic eosinophilia easily revealed by pagoda red stain. Forensic Sci Int. 2008;181:21-5 pubmed publisher
  • immunohistochemistry; human; 1:100
Buckley M, Walls A. Identification of mast cells and mast cell subpopulations. Methods Mol Med. 2008;138:285-97 pubmed publisher
  • immunohistochemistry; rat; 1:100
Hinescu M, Popescu L, Gherghiceanu M, Faussone Pellegrini M. Interstitial Cajal-like cells in rat mesentery: an ultrastructural and immunohistochemical approach. J Cell Mol Med. 2008;12:260-70 pubmed publisher
  • immunohistochemistry; human; 1:200
Osawa M, Satoh F, Horiuchi H, Tian W, Kugota N, Hasegawa I. Postmortem diagnosis of fatal anaphylaxis during intravenous administration of therapeutic and diagnostic agents: evaluation of clinical laboratory parameters and immunohistochemistry in three cases. Leg Med (Tokyo). 2008;10:143-7 pubmed
  • immunohistochemistry; human; 1:100
Gun B, Bahadir B, Behzatoglu K, Gun M, Ozdamar S. Elastofibroma: a clinicopathologic and immunohistochemical study of seven cases and literature review. APMIS. 2007;115:115-9 pubmed
  • immunohistochemistry; rat; 1:100
Popescu L, Gherghiceanu M, Hinescu M, Cretoiu D, Ceafalan L, Regalia T, et al. Insights into the interstitium of ventricular myocardium: interstitial Cajal-like cells (ICLC). J Cell Mol Med. 2006;10:429-58 pubmed
  • immunohistochemistry; mouse; 1:800
Cusi M, Del Vecchio M, Terrosi C, Savellini G, Di Genova G, La Placa M, et al. Immune-reconstituted influenza virosome containing CD40L gene enhances the immunological and protective activity of a carcinoembryonic antigen anticancer vaccine. J Immunol. 2005;174:7210-6 pubmed
Kulkarni P, Harsulkar A, M xe4 rtson A, Suutre S, M xe4 rtson A, Koks S. Mast Cells Differentiated in Synovial Fluid and Resident in Osteophytes Exalt the Inflammatory Pathology of Osteoarthritis. Int J Mol Sci. 2022;23: pubmed publisher
Altman M, Lai Y, Nolin J, Long S, Chen C, Piliponsky A, et al. Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling. J Clin Invest. 2019;129:4979-4991 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Tryptase Monoclonal Antibody (AA1)
Catalog # :
MA5-11711
Quantity :
500 µL
Price :
US 440
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Canine, Feline, Human, Non-human primate
Applications :
Immunohistochemistry (Paraffin): 1:2,000, Western Blot: 1:50
Species :
Canine, Feline, Human, Non-human primate
Clone :
AA1
Isotype :
IgG1
Storage :
4° C
Description :
Tryptase is a protein that belongs to the family of serine proteases and is primarily found in mast cells. It plays a crucial role in the immune response by cleaving and activating other proteins involved in inflammation and tissue repair. Tryptase is also involved in the regulation of blood pressure and has been implicated in various diseases, including asthma, allergies, and cardiovascular disorders. Its structure consists of four identical subunits that form a tetramer, and it is activated by proteolytic cleavage of its proenzyme form.
Immunogen :
Human mast cell tryptase purified from human lung tissues
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:2,000, Western Blot: 1:50
Aliases :
TPSG1/TPSB2/TPSAB1/TPSD1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA