This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
14-3-3 sigma Monoclonal Antibody (1433S01)
catalog :
MA5-11663
quantity :
500 µL
price :
US 496.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1433S01
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000
Kato H, Izumi K, Uenoyama A, Shiomi A, Kuo S, Feinberg S. Hypoxia induces an undifferentiated phenotype of oral keratinocytes in vitro. Cells Tissues Organs. 2014;199:393-404 pubmed publisher
  • immunohistochemistry; human; 1:100
Chen L, Yang B. 14-3-3 sigma is a useful immunohistochemical marker for diagnosing ovarian granulosa cell tumors and steroid cell tumors. Int J Gynecol Pathol. 2013;32:156-62 pubmed publisher
  • immunohistochemistry; human; 1:400
Erovic B, Kim D, Cassol C, Goldstein D, Irish J, Asa S, et al. Prognostic and predictive markers in medullary thyroid carcinoma. Endocr Pathol. 2012;23:232-42 pubmed publisher
  • immunohistochemistry; human; 1:400
Erovic B, Harris L, Jamali M, Goldstein D, Irish J, Asa S, et al. Biomarkers of parathyroid carcinoma. Endocr Pathol. 2012;23:221-31 pubmed publisher
  • immunohistochemistry; human; 1:400
Erovic B, Al Habeeb A, Harris L, Goldstein D, Kim D, Ghazarian D, et al. Identification of novel target proteins in sebaceous gland carcinoma. Head Neck. 2013;35:642-8 pubmed publisher
  • immunohistochemistry; human
Hayashi E, Kuramitsu Y, Fujimoto M, Zhang X, Tanaka T, Uchida K, et al. Proteomic profiling of differential display analysis for human oral squamous cell carcinoma: 14-3-3 ? Protein is upregulated in human oral squamous cell carcinoma and dependent on the differentiation level. Proteomics Clin Appl. 2009;3:1338-47 pubmed publisher
  • western blot; human; fig 3
Larriba M, Casado Vela J, Pendás Franco N, Peña R, Garcia de Herreros A, Berciano M, et al. Novel snail1 target proteins in human colon cancer identified by proteomic analysis. PLoS ONE. 2010;5:e10221 pubmed publisher
  • immunohistochemistry; human; 1:100
Agarwal B, Ludwig O, Collins B, Cortese C. Immunostaining as an adjunct to cytology for diagnosis of pancreatic adenocarcinoma. Clin Gastroenterol Hepatol. 2008;6:1425-31 pubmed publisher
  • immunohistochemistry; human; 1:75
Wang Z, Trope C, Suo Z, Trøen G, Yang G, Nesland J, et al. The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas. BMC Cancer. 2008;8:308 pubmed publisher
  • immunohistochemistry; human
Bhawal U, Sugiyama M, Nomura Y, Kuniyasu H, Tsukinoki K. Loss of 14-3-3 sigma protein expression and presence of human papillomavirus type 16 E6 in oral squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2008;134:1055-9 pubmed publisher
  • western blot; human
Ripperger T, von Neuhoff N, Kamphues K, Emura M, Lehmann U, Tauscher M, et al. Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas. Haematologica. 2007;92:460-8 pubmed
  • western blot; human
Lin C, Chung M, Chen W, Chien C. Growth inhibitory effect of the human NIT2 gene and its allelic imbalance in cancers. FEBS J. 2007;274:2946-56 pubmed
  • western blot; mouse
Senoo M, Pinto F, Crum C, McKeon F. p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell. 2007;129:523-36 pubmed
  • immunohistochemistry; human; 1:100
Lopez Knowles E, Hernandez S, Kogevinas M, Lloreta J, Amorós A, Tardon A, et al. The p53 pathway and outcome among patients with T1G3 bladder tumors. Clin Cancer Res. 2006;12:6029-36 pubmed
  • western blot; human
Liu Y, Liu H, Han B, Zhang J. Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis. Cancer Res. 2006;66:3248-55 pubmed
  • immunohistochemistry; human; 1:50
Hustinx S, Fukushima N, Zahurak M, Riall T, Maitra A, Brosens L, et al. Expression and prognostic significance of 14-3-3sigma and ERM family protein expression in periampullary neoplasms. Cancer Biol Ther. 2005;4:596-601 pubmed
Amaya E, Alarcón L, Martín Tapia D, Cuellar Perez F, Cano Cortina M, Ortega Olvera J, et al. Activation of the Ca2+ sensing receptor and the PKC/WNK4 downstream signaling cascade induces incorporation of ZO-2 to tight junctions and its separation from 14-3-3. Mol Biol Cell. 2019;30:2377-2398 pubmed publisher
product information
Product Type :
Antibody
Product Name :
14-3-3 sigma Monoclonal Antibody (1433S01)
Catalog # :
MA5-11663
Quantity :
500 µL
Price :
US 496.00
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human
Applications :
Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1 µg/mL
Species :
Human
Clone :
1433S01
Isotype :
IgG1, kappa
Storage :
4° C
Description :
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.
Immunogen :
Recombinant human 1433 sigma protein
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 2-4 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1 µg/mL
Aliases :
14-3-3 protein sigma; 14-3-3 sigma; 14-3-3 sigma protein; 14-3-3sigma; epithelial cell marker protein 1; Er; HGNC:10773; HME1; Mkrn3; Mme1; SFN; Stratifin; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, sigma polypeptide; Ywhas
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA