Calponin 1 Monoclonal Antibody (CALP) | Invitrogen MA5-11620 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Calponin 1 Monoclonal Antibody (CALP)

catalog :

MA5-11620

quantity :

500 µL

price :

US 472

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CALP

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:200; loading ...; fig 2e	Evdokiou A, Kanisicak O, Gierek S, BARRY A, Ivey M, Zhang X, et al. Characterization of Burn Eschar Pericytes. J Clin Med. 2020;9: pubmed publisher
immunohistochemistry; human; 1:250	Cheng Y, Sheng W, Zhou X, Wang J. Pericardial synovial sarcoma, a potential for misdiagnosis: clinicopathologic and molecular cytogenetic analysis of three cases with literature review. Am J Clin Pathol. 2012;137:142-9 pubmed publisher
immunohistochemistry; human; 1:400	Borak S, Siegal G, Reddy V, Jhala N, Jhala D. Metastatic inflammatory myofibroblastic tumor identified by EUS-FNA in mediastinal lymph nodes with ancillary FISH studies for ALK rearrangement. Diagn Cytopathol. 2012;40 Suppl 2:E118-25 pubmed publisher
immunohistochemistry; human; 1:3000	Romeo S, Eyden B, Prins F, Briaire de Bruijn I, Taminiau A, Hogendoorn P. TGF-beta1 drives partial myofibroblastic differentiation in chondromyxoid fibroma of bone. J Pathol. 2006;208:26-34 pubmed
western blot; rat; 1:500	Liu C, Zhang L, Jiang Y, Chatterjee D, Croce C, Huebner K, et al. Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment. Cancer Res. 2005;65:7790-9 pubmed
	Ferland D, Darios E, Neubig R, Sjögren B, Truong N, Torres R, et al. Chemerin-induced arterial contraction is Gi- and calcium-dependent. Vascul Pharmacol. 2017;88:30-41 pubmed publisher
	Pizzagalli F, Varga Z, Huber R, Folkers G, Meier P, St Pierre M. Identification of steroid sulfate transport processes in the human mammary gland. J Clin Endocrinol Metab. 2003;88:3902-12 pubmed

image

image 1 :

Formalin-fixed, paraffin-embedded human breast stained with Calponin antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of myoepithelial cells in the lactiferous ducts.

product information

Product Type :

Antibody

Product Name :

Calponin 1 Monoclonal Antibody (CALP)

Catalog # :

MA5-11620

Quantity :

500 µL

Pricing :

US 472

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:800-1:1600, Western Blot: 1:1,000

Species :

Human, Mouse, Rat

Clone :

CALP

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.

Immunogen :

Crude human uterus extract

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:800-1:1600, Western Blot: 1:1,000

Aliases :

Basic calponin; calponin; calponin 1; calponin 1, basic, smooth muscle; calponin 1, smooth muscle; calponin H1, smooth muscle; Calponin-1; calponins, basic; CN; CNN1; CnnI; epididymis secretory protein Li 14; h1-calponin; HEL-S-14; similar to calponin 1, basic, smooth muscle; Sm-Calp; SMCC; smooth muscle calponin h1

more info or order :

Invitrogen product webpage