product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 14 Monoclonal Antibody (LL002)
catalog :
MA5-11599
quantity :
500 µL
price :
US 379
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
LL002
reactivity :
human, mouse, rat, dogs, cat, domestic sheep, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 144
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 1c
Schünke H, Göbel U, Dikic I, Pasparakis M. OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice. Nat Commun. 2021;12:5912 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1600; loading ...; fig 3b
DeLaForest A, Kohlnhofer B, Franklin O, Stavniichuk R, Thompson C, Pulakanti K, et al. GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium. Cell Mol Gastroenterol Hepatol. 2021;12:1391-1413 pubmed publisher
  • immunohistochemistry; mouse; 1:800; fig 2c
Chen M, Reed R, Lane A. Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense. Cell Stem Cell. 2019;25:501-513.e5 pubmed publisher
  • immunohistochemistry; dogs; loading ...; fig 5a
Pin D, Pendaries V, Keita Alassane S, Froment C, Amalric N, Cadiergues M, et al. Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin. J Histochem Cytochem. 2019;67:85-97 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4e
Liao C, Booker R, Morrison S, Le L. Identification of hair shaft progenitors that create a niche for hair pigmentation. Genes Dev. 2017;31:744-756 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 3n
Anderson P, Lynch T, Engelhardt J. Multipotent Myoepithelial Progenitor Cells Are Born Early during Airway Submucosal Gland Development. Am J Respir Cell Mol Biol. 2017;56:716-726 pubmed publisher
  • immunocytochemistry; human; 1:25; loading ...; fig 2
Hopkinson B, Klitgaard M, Petersen O, Villadsen R, Rønnov Jessen L, Kim J. Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype. Oncotarget. 2017;8:10580-10593 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6a
Pamarthy S, Mao L, Katara G, Fleetwood S, Kulshreshta A, Gilman Sachs A, et al. The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling. Cell Death Dis. 2016;7:e2443 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:800; fig 8
Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher
  • immunocytochemistry; human; fig 2d
  • western blot; human
  • immunohistochemistry; mouse; loading ...; fig 1a
Kuga T, Sasaki M, Mikami T, Miake Y, Adachi J, Shimizu M, et al. FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes. Sci Rep. 2016;6:26557 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:300; fig 1
Stewart M, Plante I, Penuela S, Laird D. Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis. PLoS ONE. 2016;11:e0154162 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1
Mandasari M, Sawangarun W, Katsube K, Kayamori K, Yamaguchi A, Sakamoto K. A facile one-step strategy for the generation of conditional knockout mice to explore the role of Notch1 in oroesophageal tumorigenesis. Biochem Biophys Res Commun. 2016;469:761-7 pubmed publisher
  • immunocytochemistry; human; 1:25; fig 2a
Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al. Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nat Commun. 2015;6:8786 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 5
Stewart M, Bechberger J, Welch I, Naus C, Laird D. Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer. Oncotarget. 2015;6:37185-99 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25; loading ...; fig 1b
Kajimura J, Ito R, Manley N, Hale L. Optimization of Single- and Dual-Color Immunofluorescence Protocols for Formalin-Fixed, Paraffin-Embedded Archival Tissues. J Histochem Cytochem. 2016;64:112-24 pubmed publisher
  • immunohistochemistry; human
Gromova I, Gromov P, Honma N, Kumar S, Rimm D, Talman M, et al. High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy. Mol Oncol. 2015;9:1636-54 pubmed publisher
  • immunohistochemistry; human; 1:100
Matsusaki M, Fujimoto K, Shirakata Y, Hirakawa S, Hashimoto K, Akashi M. Development of full-thickness human skin equivalents with blood and lymph-like capillary networks by cell coating technology. J Biomed Mater Res A. 2015;103:3386-96 pubmed publisher
  • immunohistochemistry - paraffin section; cat; 1:300
  • immunohistochemistry - paraffin section; dogs; 1:300
Muscatello L, Sarli G, Beha G, Asproni P, Millanta F, Poli A, et al. Validation of tissue microarray for molecular profiling of canine and feline mammary tumours. J Comp Pathol. 2015;152:153-60 pubmed publisher
  • immunohistochemistry; human; fig 1
Ouyang H, Xue Y, Lin Y, Zhang X, Xi L, Patel S, et al. WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature. 2014;511:358-61 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500
Kutten J, McGovern D, Hobson C, Luffy S, Nieponice A, Tobita K, et al. Decellularized tracheal extracellular matrix supports epithelial migration, differentiation, and function. Tissue Eng Part A. 2015;21:75-84 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Kim C, Pasparakis M. Epidermal p65/NF-?B signalling is essential for skin carcinogenesis. EMBO Mol Med. 2014;6:970-83 pubmed publisher
  • immunohistochemistry - paraffin section; human
Kaisani A, Delgado O, Fasciani G, Kim S, Wright W, Minna J, et al. Branching morphogenesis of immortalized human bronchial epithelial cells in three-dimensional culture. Differentiation. 2014;87:119-26 pubmed publisher
  • immunohistochemistry; human; 1:100
Tse G, Ni Y, Tsang J, Shao M, Huang Y, Luo M, et al. Immunohistochemistry in the diagnosis of papillary lesions of the breast. Histopathology. 2014;65:839-53 pubmed publisher
  • immunohistochemistry; dogs; 1:2000
Banco B, Grieco V, Di Giancamillo M, Greci V, Travetti O, Martino P, et al. Canine aural cholesteatoma: a histological and immunohistochemical study. Vet J. 2014;200:440-5 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Wansleeben C, Bowie E, Hotten D, Yu Y, Hogan B. Age-related changes in the cellular composition and epithelial organization of the mouse trachea. PLoS ONE. 2014;9:e93496 pubmed publisher
  • immunocytochemistry; human; 1:25
  • immunohistochemistry; human; 1:25
Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed publisher
  • immunohistochemistry; human; 1:100
Tsang J, Hui S, Ni Y, Chan S, Yamaguchi R, Kwong A, et al. Lymphocytic infiltrate is associated with favorable biomarkers profile in HER2-overexpressing breast cancers and adverse biomarker profile in ER-positive breast cancers. Breast Cancer Res Treat. 2014;143:1-9 pubmed publisher
  • immunohistochemistry; human; 1:400
Verschuur Maes A, Kornegoor R, de Bruin P, Oudejans J, van Diest P. Do columnar cell lesions exist in the male breast?. Histopathology. 2014;64:818-25 pubmed publisher
  • immunohistochemistry; human; 1:2
Mei H, Nakatsu M, Baclagon E, Deng S. Frizzled 7 maintains the undifferentiated state of human limbal stem/progenitor cells. Stem Cells. 2014;32:938-45 pubmed publisher
  • immunocytochemistry; human; 1:400; fig s1
Vlug E, van de Ven R, Vermeulen J, Bult P, van Diest P, Derksen P. Nuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancer. Cell Oncol (Dordr). 2013;36:375-84 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 2
Sjödahl G, Lövgren K, Lauss M, Patschan O, Gudjonsson S, Chebil G, et al. Toward a molecular pathologic classification of urothelial carcinoma. Am J Pathol. 2013;183:681-91 pubmed publisher
  • immunohistochemistry; mouse
Hughes M, Jiang T, Lin S, Leung Y, Kobielak K, Widelitz R, et al. Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis. J Invest Dermatol. 2014;134:24-32 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; tbl 2
Xing C, Fu X, Sun X, Guo P, Li M, Dong J. Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells. PLoS ONE. 2013;8:e65538 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1c
Yockey L, Demehri S, Turkoz M, Turkoz A, Ahern P, Jassim O, et al. The absence of a microbiota enhances TSLP expression in mice with defective skin barrier but does not affect the severity of their allergic inflammation. J Invest Dermatol. 2013;133:2714-2721 pubmed publisher
  • immunohistochemistry; human; 1:500
Seibold M, Smith R, Urbanek C, Groshong S, Cosgrove G, Brown K, et al. The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium. PLoS ONE. 2013;8:e58658 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Spallotta F, Cencioni C, Straino S, Nanni S, Rosati J, Artuso S, et al. A nitric oxide-dependent cross-talk between class I and III histone deacetylases accelerates skin repair. J Biol Chem. 2013;288:11004-12 pubmed publisher
  • immunohistochemistry; human
Kobayashi T, Iwaya K, Moriya T, Yamasaki T, Tsuda H, Yamamoto J, et al. A simple immunohistochemical panel comprising 2 conventional markers, Ki67 and p53, is a powerful tool for predicting patient outcome in luminal-type breast cancer. BMC Clin Pathol. 2013;13:5 pubmed publisher
  • immunohistochemistry; human; 1:100
Luo M, Huang Y, Ni Y, Tsang J, Chan S, Shao M, et al. Expression of mammaglobin and gross cystic disease fluid protein-15 in breast carcinomas. Hum Pathol. 2013;44:1241-50 pubmed publisher
  • immunocytochemistry; human; 1:150
Fatimah S, Tan G, Chua K, Tan A, Nur Azurah A, Hayati A. Effects of keratinocyte growth factor on skin epithelial differentiation of human amnion epithelial cells. Burns. 2013;39:905-15 pubmed publisher
  • immunohistochemistry; domestic sheep; 1:100
Galio L, Droineau S, Yeboah P, Boudiaf H, Bouet S, Truchet S, et al. MicroRNA in the ovine mammary gland during early pregnancy: spatial and temporal expression of miR-21, miR-205, and miR-200. Physiol Genomics. 2013;45:151-61 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 1:300
Beha G, Brunetti B, Asproni P, Muscatello L, Millanta F, Poli A, et al. Molecular portrait-based correlation between primary canine mammary tumor and its lymph node metastasis: possible prognostic-predictive models and/or stronghold for specific treatments?. BMC Vet Res. 2012;8:219 pubmed publisher
  • immunohistochemistry; mouse; 1:100
Stewart M, Gong X, Barr K, Bai D, Fishman G, Laird D. The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice. Biochem J. 2013;449:401-13 pubmed publisher
  • immunohistochemistry; mouse
  • western blot; mouse
Simmons M, Serra R, Hermance N, Kelliher M. NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro. Breast Cancer Res. 2012;14:R126 pubmed publisher
  • immunohistochemistry; human; 1:400
Kornegoor R, Verschuur Maes A, Buerger H, Hogenes M, de Bruin P, Oudejans J, et al. Immunophenotyping of male breast cancer. Histopathology. 2012;61:1145-55 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 1:300; tbl 2
Beha G, Sarli G, Brunetti B, Sassi F, Ferrara D, Benazzi C. Morphology of the myoepithelial cell: immunohistochemical characterization from resting to motile phase. ScientificWorldJournal. 2012;2012:252034 pubmed publisher
  • immunohistochemistry; human; 1:100
Shao M, Chan S, Yu A, Lam C, Tsang J, Lui P, et al. Keratin expression in breast cancers. Virchows Arch. 2012;461:313-22 pubmed publisher
  • immunohistochemistry; cat; 1:300
Brunetti B, Asproni P, Beha G, Muscatello L, Millanta F, Poli A, et al. Molecular phenotype in mammary tumours of queens: correlation between primary tumour and lymph node metastasis. J Comp Pathol. 2013;148:206-13 pubmed publisher
  • immunohistochemistry; human; 1:400
  • western blot; mouse; 1:1000
Churko J, Kelly J, Macdonald A, Lee J, SAMPSON J, Bai D, et al. The G60S Cx43 mutant enhances keratinocyte proliferation and differentiation. Exp Dermatol. 2012;21:612-8 pubmed publisher
  • immunohistochemistry; mouse; 2 ug/ml
Odorisio T, De Luca N, Vesci L, Luisi P, Stano P, Zambruno G, et al. The atypical retinoid E-3-(3'-Adamantan-1-yl-4'-methoxybiphenyl-4-yl)-2-propenoic acid (ST1898) displays comedolytic activity in the rhino mouse model. Eur J Dermatol. 2012;22:505-11 pubmed publisher
  • immunohistochemistry; human; 1:200
Kaplan J, Schnitt S, Collins L, Wang Y, Garber J, Montgomery K, et al. Pathologic features and immunophenotype of estrogen receptor-positive breast cancers in BRCA1 mutation carriers. Am J Surg Pathol. 2012;36:1483-8 pubmed publisher
  • immunohistochemistry; human
Sjödahl G, Lauss M, Lövgren K, Chebil G, Gudjonsson S, Veerla S, et al. A molecular taxonomy for urothelial carcinoma. Clin Cancer Res. 2012;18:3377-86 pubmed publisher
  • immunohistochemistry; human; 1:100
Tsang J, Lai M, Wong K, Chan S, Lam C, Tsang A, et al. ?B-crystallin is a useful marker for triple negative and basal breast cancers. Histopathology. 2012;61:378-86 pubmed publisher
  • immunohistochemistry; human; 1:400
Kornegoor R, Verschuur Maes A, Buerger H, van Diest P. The 3-layered ductal epithelium in gynecomastia. Am J Surg Pathol. 2012;36:762-8 pubmed publisher
  • immunocytochemistry; human
Alexaki V, Pelekanou V, Notas G, Venihaki M, Kampa M, Dessirier V, et al. B-cell maturation antigen (BCMA) activation exerts specific proinflammatory effects in normal human keratinocytes and is preferentially expressed in inflammatory skin pathologies. Endocrinology. 2012;153:739-49 pubmed publisher
  • immunohistochemistry; human
Li B, Li J, Devlin B, Markert M. Thymic microenvironment reconstitution after postnatal human thymus transplantation. Clin Immunol. 2011;140:244-59 pubmed publisher
  • immunohistochemistry; human; 1:200
Yu Q, Niu Y, Liu N, Zhang J, Liu T, Zhang R, et al. Expression of androgen receptor in breast cancer and its significance as a prognostic factor. Ann Oncol. 2011;22:1288-94 pubmed publisher
  • immunohistochemistry; human; 1:200
Moreira J, Cabezon T, Gromova I, Gromov P, Timmermans Wielenga V, Machado I, et al. Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy. Mol Oncol. 2010;4:539-61 pubmed publisher
  • immunohistochemistry; human; 1:50
Giordano G, D Adda T, Brigati F, Lombardi M, Raboni S. A Unique case of primary squamous carcinoma of the salpinx associated with serous carcinoma of the omentum: a pathological and molecular study. Int J Gynecol Pathol. 2010;29:533-8 pubmed publisher
  • immunohistochemistry; human
Israr M, Mitchell D, Alam S, Dinello D, Kishel J, Meyers C. The HIV protease inhibitor lopinavir/ritonavir (Kaletra) alters the growth, differentiation and proliferation of primary gingival epithelium. HIV Med. 2011;12:145-56 pubmed publisher
  • immunohistochemistry; human
Carvalho L, Pereira E, Frappart L, Boniol M, Bernardo W, Tarricone V, et al. Molecular characterization of breast cancer in young Brazilian women. Rev Assoc Med Bras (1992). 2010;56:278-87 pubmed
  • immunocytochemistry; human; 1:20
  • immunohistochemistry; human; 1:20
Bohn O, Fuertes Camilo M, Navarro L, Saldivar J, Sanchez Sosa S. p16INK4a expression in basal-like breast carcinoma. Int J Clin Exp Pathol. 2010;3:600-7 pubmed
  • immunohistochemistry; human
Choi K, Kim G, Kim S. The keratin-14 expression in actinic keratosis and squamous cell carcinoma: is this a prognostic factor for tumor progression?. Cancer Res Treat. 2010;42:107-14 pubmed publisher
  • immunohistochemistry; human; 1:100
Huang S, Xu Y, Wu C, Sha D, Fu X. In vitro constitution and in vivo implantation of engineered skin constructs with sweat glands. Biomaterials. 2010;31:5520-5 pubmed publisher
  • immunohistochemistry; mouse
Jiang P, Hu Q, Ito M, Meyer S, Waltz S, Khan S, et al. Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation. Proc Natl Acad Sci U S A. 2010;107:6765-70 pubmed publisher
  • immunohistochemistry; mouse; 1:100
  • western blot; mouse; 1:100
Tompkins D, Besnard V, Lange A, Wert S, Keiser A, Smith A, et al. Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells. PLoS ONE. 2009;4:e8248 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Rock J, Onaitis M, Rawlins E, Lu Y, Clark C, Xue Y, et al. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci U S A. 2009;106:12771-5 pubmed publisher
  • immunohistochemistry; human; 1:50
Barcelos A, Sotto M. Comparative analysis of the expression of cytokeratins (1, 10, 14, 16, 4), involucrin, filaggrin and e-cadherin in plane warts and epidermodysplasia verruciformis plane wart-type lesions. J Cutan Pathol. 2009;36:647-54 pubmed publisher
  • immunohistochemistry; human; 1:100
Singh A, Kapur S, Chattopadhyay I, Purkayastha J, Sharma J, Mishra A, et al. Cytokeratin immunoexpression in esophageal squamous cell carcinoma of high-risk population in Northeast India. Appl Immunohistochem Mol Morphol. 2009;17:419-24 pubmed publisher
  • immunocytochemistry; human
  • immunohistochemistry; human
  • western blot; human
Celis J, Gromova I, Cabezon T, Gromov P, Shen T, Timmermans Wielenga V, et al. Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease. Mol Oncol. 2007;1:321-49 pubmed publisher
  • immunohistochemistry; human
  • western blot; human; 1:2000
Celis J, Moreira J, Gromova I, Cabezon T, Gromov P, Shen T, et al. Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia. Mol Oncol. 2007;1:97-119 pubmed publisher
  • immunohistochemistry; human
Burga L, Tung N, Troyan S, Bostina M, Konstantinopoulos P, Fountzilas H, et al. Altered proliferation and differentiation properties of primary mammary epithelial cells from BRCA1 mutation carriers. Cancer Res. 2009;69:1273-8 pubmed publisher
  • immunohistochemistry; human; 1:400
Kapucuoglu N, Percinel S, Ventura T, Lang R, Al Daraji W, Eusebi V. Dendritic cell sarcomas/tumours of the breast: report of two cases. Virchows Arch. 2009;454:333-9 pubmed publisher
  • immunohistochemistry; human; 1:100
Dogu G, Ozkan M, Ozturk F, Dikilitas M, Er O, Ozturk A. Triple-negative breast cancer: immunohistochemical correlation with basaloid markers and prognostic value of survivin. Med Oncol. 2010;27:34-9 pubmed publisher
  • immunohistochemistry; human; 1:100
Li H, Zhou G, Fu X, Zhang L. Antigen expression of human eccrine sweat glands. J Cutan Pathol. 2009;36:318-24 pubmed publisher
  • immunohistochemistry; human; 1:50
Da Silva L, Buck L, Simpson P, Reid L, McCallum N, Madigan B, et al. Molecular and morphological analysis of adenoid cystic carcinoma of the breast with synchronous tubular adenosis. Virchows Arch. 2009;454:107-14 pubmed publisher
  • immunohistochemistry; mouse
Luo X, Okubo T, Randell S, Hogan B. Culture of endodermal stem/progenitor cells of the mouse tongue. In Vitro Cell Dev Biol Anim. 2009;45:44-54 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:400
  • immunohistochemistry; human; 1:400
Boone J, van Hillegersberg R, van Diest P, Offerhaus G, Rinkes I, Kate F. Validation of tissue microarray technology in squamous cell carcinoma of the esophagus. Virchows Arch. 2008;452:507-14 pubmed publisher
  • flow cytometry; rat
Kurzrock E, Lieu D, deGraffenried L, Chan C, Isseroff R. Label-retaining cells of the bladder: candidate urothelial stem cells. Am J Physiol Renal Physiol. 2008;294:F1415-21 pubmed publisher
  • western blot; human
Quinchia Rios B, Guerrero M, Abozeid S, Bainbridge B, Darveau R, Compton T, et al. Down-regulation of epidermal growth factor receptor-dependent signaling by Porphyromonas gingivalis lipopolysaccharide in life-expanded human gingival fibroblasts. J Periodontal Res. 2008;43:290-304 pubmed publisher
  • immunohistochemistry; human; 1:50
Lourenço S, Uyekita S, Lima D, Soares F. Developing human minor salivary glands: morphological parallel relation between the expression of TGF-beta isoforms and cytoskeletal markers of glandular maturation. Virchows Arch. 2008;452:427-34 pubmed
  • immunohistochemistry; human
Liu H, Fan Q, Zhang Z, Li X, Yu H, Meng F. Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancers. Hum Pathol. 2008;39:167-74 pubmed
  • immunohistochemistry; human; 1:400
van der Groep P, Bouter A, Menko F, van der Wall E, van Diest P. High frequency of HIF-1alpha overexpression in BRCA1 related breast cancer. Breast Cancer Res Treat. 2008;111:475-80 pubmed
  • immunohistochemistry; rhesus macaque; 1:100
Wood C, Hester J, Cline J. Mammary gland development in early pubertal female macaques. Toxicol Pathol. 2007;35:795-805 pubmed
  • immunohistochemistry; human; 1:1000; tbl 3
Goldstein N, Decker D, Severson D, Schell S, Vicini F, Margolis J, et al. Molecular classification system identifies invasive breast carcinoma patients who are most likely and those who are least likely to achieve a complete pathologic response after neoadjuvant chemotherapy. Cancer. 2007;110:1687-96 pubmed
  • immunohistochemistry; human; 1:100
Froio E, D Adda T, Fellegara G, Ampollini L, Carbognani P, Rindi G. Three different synchronous primary lung tumours: a case report with extensive genetic analysis and review of the literature. Lung Cancer. 2008;59:395-402 pubmed
  • immunohistochemistry; human; 1:50
Lourenço S, Coutinho Camillo C, Buim M, Uyekita S, Soares F. Human salivary gland branching morphogenesis: morphological localization of claudins and its parallel relation with developmental stages revealed by expression of cytoskeleton and secretion markers. Histochem Cell Biol. 2007;128:361-9 pubmed
  • immunohistochemistry; human; 1:100
Wearne K, Winter H, Goldstein I. Temporal changes in the carbohydrates expressed on BG01 human embryonic stem cells during differentiation as embryoid bodies. Glycoconj J. 2008;25:121-36 pubmed
  • immunohistochemistry; human; 1:1000
Kazakov D, Calonje E, Rutten A, Glatz K, Michal M. Cutaneous sebaceous neoplasms with a focal glandular pattern (seboapocrine lesions): a clinicopathological study of three cases. Am J Dermatopathol. 2007;29:359-64 pubmed
  • western blot; human; 1:100
Long R, Morrissey C, Walsh S, Hamilton H, Farrell N, O Neill A, et al. Alterations in the expression of inhibitors of apoptosis during differentiation of prostate epithelial cells. BJU Int. 2007;100:445-9 pubmed
  • immunohistochemistry; human; 1:1000
Soares A, Juliano P, Araujo V, Metze K, Altemani A. Angiogenic switch during tumor progression of carcinoma ex-pleomorphic adenoma. Virchows Arch. 2007;451:65-71 pubmed
  • immunohistochemistry; mouse
Que J, Okubo T, Goldenring J, Nam K, Kurotani R, Morrisey E, et al. Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development. 2007;134:2521-31 pubmed
  • immunohistochemistry; human; 1:100
  • western blot; human; 1:1000
Murata K, Ota S, Niki T, Goto A, Li C, Ruriko U, et al. p63 - Key molecule in the early phase of epithelial abnormality in idiopathic pulmonary fibrosis. Exp Mol Pathol. 2007;83:367-76 pubmed
  • immunohistochemistry; rat
Chen W, Hara K, Tian Q, Zhao K, Yoshitomi T. Existence of small slow-cycling Langerhans cells in the limbal basal epithelium that express ABCG2. Exp Eye Res. 2007;84:626-34 pubmed
  • immunohistochemistry; human; 1:100
Li H, Cherukuri P, Li N, Cowling V, Spinella M, Cole M, et al. Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors. Cancer Res. 2007;67:501-10 pubmed
  • immunohistochemistry; mouse; 2.1 ug/ml
Sleeman K, Kendrick H, Robertson D, Isacke C, Ashworth A, Smalley M. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. J Cell Biol. 2007;176:19-26 pubmed
  • western blot; human; 1:100
Chung J, Braunschweig T, Hu N, Roth M, Traicoff J, Wang Q, et al. A multiplex tissue immunoblotting assay for proteomic profiling: a pilot study of the normal to tumor transition of esophageal squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 2006;15:1403-8 pubmed
  • immunohistochemistry; human; 1:50
de Araujo V, Altemani A, Furuse C, Martins M, de Araujo N. Immunoprofile of reactive salivary myoepithelial cells in intraductal areas of carcinoma ex-pleomorphic adenoma. Oral Oncol. 2006;42:1011-6 pubmed
  • immunohistochemistry; human; 1:100
Tse G, Tan P, Lui P, Gilks C, Poon C, Ma T, et al. The role of immunohistochemistry for smooth-muscle actin, p63, CD10 and cytokeratin 14 in the differential diagnosis of papillary lesions of the breast. J Clin Pathol. 2007;60:315-20 pubmed
  • immunohistochemistry; human; 1:1000
Kazakov D, Mukensnabl P, Michal M. An unusual hamartoma of the folliculosebaceous-apocrine unit: a case report. J Cutan Pathol. 2006;33:365-8 pubmed
  • immunocytochemistry; mouse; 2.1 ug/ml
Sleeman K, Kendrick H, Ashworth A, Isacke C, Smalley M. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Res. 2006;8:R7 pubmed
  • immunohistochemistry; human; 1:100
Mete O, Kilicaslan I, Gulluoglu M, Uysal V. Can renal oncocytoma be differentiated from its renal mimics? The utility of anti-mitochondrial, caveolin 1, CD63 and cytokeratin 14 antibodies in the differential diagnosis. Virchows Arch. 2005;447:938-46 pubmed
  • immunohistochemistry; mouse; 1:200
Rawlins E, Hogan B. Intercellular growth factor signaling and the development of mouse tracheal submucosal glands. Dev Dyn. 2005;233:1378-85 pubmed
  • immunohistochemistry; human; 1:1000
Altemani A, Martins M, Freitas L, Soares F, Araujo N, Araujo V. Carcinoma ex pleomorphic adenoma (CXPA): immunoprofile of the cells involved in carcinomatous progression. Histopathology. 2005;46:635-41 pubmed
  • immunohistochemistry; human; 1:1000
Kazakov D, Mikyskova I, Mukensnabl P, Brouckova M, Treska V, Hes O, et al. Reactive syringofibroadenomatous hyperplasia in peristomal skin with formation of hybrid epidermal-colonic mucosa glandular structures, intraepidermal areas of sebaceous differentiation, induction of hair follicles, and features of human papillomavir. Am J Dermatopathol. 2005;27:135-41 pubmed
  • immunohistochemistry - paraffin section; human; 1:500
Chung C, Parker J, Karaca G, Wu J, Funkhouser W, Moore D, et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cell. 2004;5:489-500 pubmed
Forte E, Ramialison M, Nim H, Mara M, Li J, Cohn R, et al. Adult mouse fibroblasts retain organ-specific transcriptomic identity. elife. 2022;11: pubmed publisher
Portal C, Wang Z, Scott D, Wolosin J, Iomini C. The c-Myc Oncogene Maintains Corneal Epithelial Architecture at Homeostasis, Modulates p63 Expression, and Enhances Proliferation During Tissue Repair. Invest Ophthalmol Vis Sci. 2022;63:3 pubmed publisher
Eksi S, Chitsazan A, Sayar Z, Thomas G, Fields A, Kopp R, et al. Epigenetic loss of heterogeneity from low to high grade localized prostate tumours. Nat Commun. 2021;12:7292 pubmed publisher
Parisi F, Muscatello L, Civita P, Lessi F, Menicagli M, Millanta F, et al. Pathological Features and Molecular Phenotype of MMTV Like-Positive Feline Mammary Carcinomas. Animals (Basel). 2021;11: pubmed publisher
Bolf E, Gillis N, Davidson C, Cozzens L, Kogut S, Tomczak J, et al. Common tumor-suppressive signaling of thyroid hormone receptor beta in breast and thyroid cancer cells. Mol Carcinog. 2021;60:874-885 pubmed publisher
Weber M, Eibauer M, Sivagurunathan S, Magin T, Goldman R, Medalia O. Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy. elife. 2021;10: pubmed publisher
Gong W, Qiao Y, Li B, Zheng X, Xu R, Wang M, et al. The Alteration of Salivary Immunoglobulin A in Autism Spectrum Disorders. Front Psychiatry. 2021;12:669193 pubmed publisher
Huang W, Zheng X, Yang M, Li R, Song Y. PER2-mediated ameloblast differentiation via PPARγ/AKT1/β-catenin axis. Int J Oral Sci. 2021;13:16 pubmed publisher
Pastushenko I, Mauri F, Song Y, De Cock F, Meeusen B, Swedlund B, et al. Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis. Nature. 2021;589:448-455 pubmed publisher
Kelel M, Yang R, Tsai T, Liang P, Wu F, Huang Y, et al. FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development. J Invest Dermatol. 2021;141:512-522 pubmed publisher
Li H, Chaitankar V, Zhu J, Chin K, Liu W, Pirooznia M, et al. Olfactomedin 4 mediation of prostate stem/progenitor-like cell proliferation and differentiation via MYC. Sci Rep. 2020;10:21924 pubmed publisher
Ognjenovic N, Bagheri M, Mohamed G, Xu K, Chen Y, Mohamed Saleem M, et al. Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors. Dev Cell. 2020;55:544-557.e6 pubmed publisher
Subramaniyan B, Sridharan S, M Howard C, M C Tilley A, Basuroy T, DE LA SERNA I, et al. Role of the CXCR4-LASP1 Axis in the Stabilization of Snail1 in Triple-Negative Breast Cancer. Cancers (Basel). 2020;12: pubmed publisher
Jiao H, Wachsmuth L, Kumari S, Schwarzer R, Lin J, Eren R, et al. Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation. Nature. 2020;580:391-395 pubmed publisher
Kumai A, Tsugami Y, Wakasa H, Suzuki N, Suzuki T, Nishimura T, et al. Adverse Effects of Coumestrol and Genistein on Mammary Morphogenesis and Future Milk Production Ability of Mammary Epithelial Cells. Adv Biosyst. 2020;4:e1900187 pubmed publisher
Schwartz C, Stack J, Hill C, Lallier S, Chiang T, Johnson J, et al. Electrospun scaffolds limit the regenerative potential of the airway epithelium. Laryngoscope Investig Otolaryngol. 2019;4:446-454 pubmed publisher
Song L, Song Z, Fry N, Conatser L, Llanga T, Mei H, et al. Gene Delivery to Human Limbal Stem Cells Using Viral Vectors. Hum Gene Ther. 2019;30:1336-1348 pubmed publisher
Danzinger S, Tan Y, Rudas M, Kastner M, Weingartshofer S, Muhr D, et al. Association of Cytokeratin 5 and Claudin 3 expression with BRCA1 and BRCA2 germline mutations in women with early breast cancer. BMC Cancer. 2019;19:695 pubmed publisher
Yang Q, Lopez M. Ultrastructural morphology is distinct among primary progenitor cell isolates from normal, inflamed, and cryopreserved equine hoof tissue and CD105+K14+ progenitor cells. In Vitro Cell Dev Biol Anim. 2019;55:641-655 pubmed publisher
Ren G, Zheng X, Bommarito M, Metzger S, Walia Y, Letson J, et al. Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ. Sci Rep. 2019;9:6688 pubmed publisher
Zhu Q, Fang L, Heuberger J, Kranz A, Schipper J, Scheckenbach K, et al. The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer. Cell Rep. 2019;26:415-428.e5 pubmed publisher
Chamberlin T, D Amato J, Arendt L. Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity. Breast Cancer Res. 2017;19:128 pubmed publisher
Watanabe K, Chambers J, Uchida K, Nibe K, Ushio N, Horiuchi N, et al. A cutaneous mixed tumor in a dog. J Vet Med Sci. 2017;79:670-673 pubmed publisher
Liu Y, Wang K, Xing H, Zhai X, Wang L, Wang W. Attempt towards a novel classification of triple-negative breast cancer using immunohistochemical markers. Oncol Lett. 2016;12:1240-1256 pubmed
Fong L, Taccioli C, Jing R, Smalley K, Alder H, Jiang Y, et al. MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency. Oncotarget. 2016;7:10723-38 pubmed publisher
Aho S. Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases. Exp Dermatol. 2004;13:700-7 pubmed
Chang Y, Liu H, Wang W, Lee D, Tsai S. A study of cytokeratin profiles in localized cutaneous amyloids. Arch Dermatol Res. 2004;296:83-8 pubmed
Apaydin R, Gurbuz Y, Bayramgurler D, Muezzinoglu B, Bilen N. Cytokeratin expression in lichen amyloidosus and macular amyloidosis. J Eur Acad Dermatol Venereol. 2004;18:305-9 pubmed
Hale L, Buckley R, Puck J, Patel D. Abnormal development of thymic dendritic and epithelial cells in human X-linked severe combined immunodeficiency. Clin Immunol. 2004;110:63-70 pubmed
Hale L, Markert M. Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. J Immunol. 2004;172:617-24 pubmed
Dillman J, McGary K, Schlager J. Sulfur mustard induces the formation of keratin aggregates in human epidermal keratinocytes. Toxicol Appl Pharmacol. 2003;193:228-36 pubmed
Furuse C, Tucci R, Machado de Sousa S, Rodarte Carvalho Y, Cavalcanti de Araujo V. Comparative immunoprofile of polymorphous low-grade adenocarcinoma and canalicular adenoma. Ann Diagn Pathol. 2003;7:278-80 pubmed
Sørensen C, Andresen B, Jensen U, Jensen T, Jensen P, Gregersen N, et al. Functional testing of keratin 14 mutant proteins associated with the three major subtypes of epidermolysis bullosa simplex. Exp Dermatol. 2003;12:472-9 pubmed
de Araujo V, Kowalski L, Soares F, de Araujo N, Loducca S, Sobral A. Salivary duct carcinoma: cytokeratin 14 as a marker of in-situ intraductal growth. Histopathology. 2002;41:244-9 pubmed
Hsu W, Shakya R, Costantini F. Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice. J Cell Biol. 2001;155:1055-64 pubmed
Woodward T, Mienaltowski A, Modi R, Bennett J, Haslam S. Fibronectin and the alpha(5)beta(1) integrin are under developmental and ovarian steroid regulation in the normal mouse mammary gland. Endocrinology. 2001;142:3214-22 pubmed
Rossiter H, Beissert S, Mayer C, Schön M, Wienrich B, Tschachler E, et al. Targeted expression of bcl-2 to murine basal epidermal keratinocytes results in paradoxical retardation of ultraviolet- and chemical-induced tumorigenesis. Cancer Res. 2001;61:3619-26 pubmed
Müller Röver S, Rossiter H, Paus R, Handjiski B, Peters E, Murphy J, et al. Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopecia. Am J Pathol. 2000;156:1395-405 pubmed
image
image 1 :
Invitrogen MA5-11599 image 1
product information
Product Type :
Antibody
Product Name :
Cytokeratin 14 Monoclonal Antibody (LL002)
Catalog # :
MA5-11599
Quantity :
500 µL
Pricing :
US 379
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:800 - 1600, Western Blot: 1-2 µg/mL
Species :
Human, Mouse, Rat
Clone :
LL002
Isotype :
IgG3, kappa
Storage :
4° C
Description :
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
Immunogen :
A synthetic peptide of 15 amino acid residues from the C-terminus of human keratin 14
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1:800 - 1600, Western Blot: 1-2 µg/mL
Aliases :
AI626930; CK14; CK-14; cytokeratin 14; cytokeratin-14; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; Ka14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin, type I cytoskeletal 17; keratin-14; Koebner; Krt-1.14; Krt1-14; KRT14; LOC100737113; NFJ; Type I keratin Ka14
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA