CD56 Monoclonal Antibody (56C04) | Invitrogen MA5-11563 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD56 Monoclonal Antibody (56C04)

catalog :

MA5-11563

quantity :

500 µL

price :

US 472

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

56C04

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; fig 1c	Senbabaoglu Y, Gejman R, Winer A, Liu M, Van Allen E, de Velasco G, et al. Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biol. 2016;17:231 pubmed
immunohistochemistry - paraffin section; human; fig 1d	Abdelgawad M, Delaisse J, Hinge M, Jensen P, Alnaimi R, Rolighed L, et al. Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts. Histochem Cell Biol. 2016;145:603-15 pubmed publisher
immunohistochemistry - paraffin section; human	Chen Q, Gu Y, Liu B. Clinicopathological characteristics of kidney mucinous tubular and spindle cell carcinoma. Int J Clin Exp Pathol. 2015;8:1007-12 pubmed
immunohistochemistry; human	Kristensen H, Andersen T, Marcussen N, Rolighed L, Delaisse J. Increased presence of capillaries next to remodeling sites in adult human cancellous bone. J Bone Miner Res. 2013;28:574-85 pubmed publisher
immunohistochemistry; human; 1:100	Zhao L, Luo J, Zhang H, Da J. Pigmented paraganglioma of the kidney: a case report. Diagn Pathol. 2012;7:77 pubmed publisher
immunohistochemistry; human	Tamaska J, Adam E, Kozma A, Gopcsa L, Andrikovics H, Tordai A, et al. Hepatosplenic gammadelta T-cell lymphoma with ring chromosome 7, an isochromosome 7q equivalent clonal chromosomal aberration. Virchows Arch. 2006;449:479-83 pubmed
	Yeola A, Subramanian S, Oliver R, Lucas C, Thoms J, Yan F, et al. Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine. Sci Adv. 2021;7: pubmed publisher
	Kapchinsky S, Vuda M, Miguez K, Elkrief D, de Souza A, Baglole C, et al. Smoke-induced neuromuscular junction degeneration precedes the fibre type shift and atrophy in chronic obstructive pulmonary disease. J Physiol. 2018;596:2865-2881 pubmed publisher
	Jensen P, Andersen T, Søe K, Hauge E, Bollerslev J, Amling M, et al. Premature loss of bone remodeling compartment canopies is associated with deficient bone formation: a study of healthy individuals and patients with Cushing's syndrome. J Bone Miner Res. 2012;27:770-80 pubmed publisher
	Sonzogni A, Colloredo G, Fabris L, Cadamuro M, Paris B, Roffi L, et al. Isolated idiopathic bile ductular hyperplasia in patients with persistently abnormal liver function tests. J Hepatol. 2004;40:592-8 pubmed

image

image 1 :

Formalin-fixed, paraffin-embedded human neuroblastoma stained with CD56 antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of tumor cells.

product information

Product Type :

Antibody

Product Name :

CD56 Monoclonal Antibody (56C04)

Catalog # :

MA5-11563

Quantity :

500 µL

Pricing :

US 472

Clonality :

Monoclonal

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1:100-1:500

Species :

Human, Rat

Clone :

56C04

Isotype :

IgG1, kappa

Storage :

4° C

Description :

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.

Immunogen :

Membrane preparation of a small cell lung carcinoma

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1-2 µg/mL, Western Blot: 1:100-1:500

Aliases :

adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM

more info or order :

Invitrogen product webpage