Caspase 6 Monoclonal Antibody (6CSP03 (14.1.190)) | Invitrogen MA5-11527 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caspase 6 Monoclonal Antibody (6CSP03 (14.1.190))

catalog :

MA5-11527

quantity :

500µL

price :

425.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6CSP03 (14.1.190)

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; fig 5a	Song S, Wang Y, Xu P, Yang R, Ma Z, Liang S, et al. The inhibition of histone deacetylase 8 suppresses proliferation and inhibits apoptosis in gastric adenocarcinoma. Int J Oncol. 2015;47:1819-28 pubmed publisher
western blot; human	Lee A, Champagne N, Wang X, Su X, Goodyer C, LeBlanc A. Alternatively spliced caspase-6B isoform inhibits the activation of caspase-6A. J Biol Chem. 2010;285:31974-84 pubmed publisher
western blot; human; 1:250	Klaiman G, Champagne N, LeBlanc A. Self-activation of Caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells. Biochim Biophys Acta. 2009;1793:592-601 pubmed publisher
immunohistochemistry; human	Blazquez S, Sirvent J, Olona M, Aguilar C, Pelegri A, Garcia J, et al. Caspase-3 and caspase-6 in ductal breast carcinoma: a descriptive study. Histol Histopathol. 2006;21:1321-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Caspase 6 Monoclonal Antibody (6CSP03 (14.1.190))

Catalog # :

MA5-11527

Quantity :

500µL

Price (USD) :

425.00 USD

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Species :

Human

Clone :

6CSP03 (14.1.190)

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Immunogen :

Recombinant human caspase 6 prodomain

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL

Aliases :

apoptotic protease MCH-2; Casp6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2