Caspase 3 Monoclonal Antibody (3CSP03 (4.1.18)) | Invitrogen MA5-11521 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caspase 3 Monoclonal Antibody (3CSP03 (4.1.18))

catalog :

MA5-11521

quantity :

500 uL

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3CSP03 (4.1.18)

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 8

Reference
Deng Q, Wu L, Li Y, Zou L. MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells. Adv Clin Exp Med. 2021;30:957-966 pubmed publisher
Ullah M, Liu D, Rai S, Razavi M, Concepcion W, Thakor A. Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury. Stem Cell Res Ther. 2020;11:398 pubmed publisher
Kilicdag H, Daglioglu Y, Erdogan S, Zorludemir S. Effects of caffeine on neuronal apoptosis in neonatal hypoxic-ischemic brain injury. J Matern Fetal Neonatal Med. 2014;27:1470-5 pubmed publisher
Mitra A, Castelao J, Hawes D, Tsao Wei D, Jiang X, Shi S, et al. Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program. Cancer. 2013;119:756-65 pubmed publisher
Mattila R, Rautava J, SyrjÃ¤nen S. Human papillomavirus in oral atrophic lichen planus lesions. Oral Oncol. 2012;48:980-984 pubmed publisher
Filis K, Kavantzas N, Isopoulos T, Antonakis P, Sigalas P, Vavouranakis E, et al. Increased vein wall apoptosis in varicose vein disease is related to venous hypertension. Eur J Vasc Endovasc Surg. 2011;41:533-9 pubmed publisher
Yoo J, Jung J, Lee M, Seo K, Shim B, Kim S, et al. Immunohistochemical analysis of non-small cell lung cancer: correlation with clinical parameters and prognosis. J Korean Med Sci. 2007;22:318-25 pubmed
Blazquez S, Sirvent J, Olona M, Aguilar C, Pelegri A, Garcia J, et al. Caspase-3 and caspase-6 in ductal breast carcinoma: a descriptive study. Histol Histopathol. 2006;21:1321-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Caspase 3 Monoclonal Antibody (3CSP03 (4.1.18))

Catalog # :

MA5-11521

Quantity :

500 uL

Price :

US 524.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1-2 ug/mL, Immunoprecipitation: 2 ug/mg protein lysate, Western Blot: 1 ug/mL

Species :

Human

Clone :

3CSP03 (4.1.18)

Isotype :

IgG2a

Storage :

4 C

Description :

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Immunogen :

Recombinant full length human Caspase 3 protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Paraffin): 1-2 ug/mL, Immunoprecipitation: 2 ug/mg protein lysate, Western Blot: 1 ug/mL

Aliases :

A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein