product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Myogenin Monoclonal Antibody (F5D)
catalog :
MA5-11486
quantity :
500 µL
price :
US 472
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F5D
reactivity :
human, mouse, rat, cat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; tbl 1
Cakici C, Buyrukcu B, Duruksu G, Haliloglu A, Aksoy A, Isik A, et al. Recovery of fertility in azoospermia rats after injection of adipose-tissue-derived mesenchymal stem cells: the sperm generation. Biomed Res Int. 2013;2013:529589 pubmed publisher
  • immunohistochemistry; human
Deng F, Galvan K, de la Roza G, Zhang S, Souid A, Stein C. Molecular characterization of an EWSR1-POU5F1 fusion associated with a t(6;22) in an undifferentiated soft tissue sarcoma. Cancer Genet. 2011;204:423-9 pubmed publisher
  • immunohistochemistry; rat
Adas G, Arikan S, Karatepe O, Kemik O, Ayhan S, Karaoz E, et al. Mesenchymal stem cells improve the healing of ischemic colonic anastomoses (experimental study). Langenbecks Arch Surg. 2011;396:115-26 pubmed publisher
  • immunocytochemistry; human; 1:1
Karaoz E, Okçu A, Gacar G, Sağlam O, Yuruker S, Kenar H. A comprehensive characterization study of human bone marrow mscs with an emphasis on molecular and ultrastructural properties. J Cell Physiol. 2011;226:1367-82 pubmed publisher
  • immunohistochemistry; human
Colella R, Mameli M, Bellezza G, Sordo R, Cavaliere A, Sidoni A. Endometriosis-associated skeletal muscle regeneration: a hitherto undescribed entity and a potential diagnostic pitfall. Am J Surg Pathol. 2010;34:10-7 pubmed publisher
  • immunocytochemistry; human
Karaoz E, Doğan B, Aksoy A, Gacar G, Akyuz S, Ayhan S, et al. Isolation and in vitro characterisation of dental pulp stem cells from natal teeth. Histochem Cell Biol. 2010;133:95-112 pubmed publisher
  • immunocytochemistry; rat
Karaoz E, Aksoy A, Ayhan S, Sariboyaci A, Kaymaz F, Kasap M. Characterization of mesenchymal stem cells from rat bone marrow: ultrastructural properties, differentiation potential and immunophenotypic markers. Histochem Cell Biol. 2009;132:533-46 pubmed publisher
  • immunohistochemistry; human; 1:50
Mukhopadhyay S, El Zammar O, Katzenstein A. Pulmonary meningothelial-like nodules: new insights into a common but poorly understood entity. Am J Surg Pathol. 2009;33:487-95 pubmed publisher
Richardson L, Wang D, Hughes R, Johnson C, Peckham M. RNA-Seq analysis of a Pax3-expressing myoblast clone in-vitro and effect of culture surface stiffness on differentiation. Sci Rep. 2022;12:2841 pubmed publisher
Malacarne C, Galbiati M, Giagnorio E, Cavalcante P, Salerno F, Andreetta F, et al. Dysregulation of Muscle-Specific MicroRNAs as Common Pathogenic Feature Associated with Muscle Atrophy in ALS, SMA and SBMA: Evidence from Animal Models and Human Patients. Int J Mol Sci. 2021;22: pubmed publisher
Thakur S, Swiderski K, Chhen V, James J, Cranna N, Islam A, et al. HSP70 drives myoblast fusion during C2C12 myogenic differentiation. Biol Open. 2020;9: pubmed publisher
Gopinath S. Inhibition of Stat3 signaling ameliorates atrophy of the soleus muscles in mice lacking the vitamin D receptor. Skelet Muscle. 2017;7:2 pubmed publisher
Pumberger M, Qazi T, Ehrentraut M, Textor M, Kueper J, Stoltenburg Didinger G, et al. Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration. Biomaterials. 2016;99:95-108 pubmed publisher
Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini P, et al. Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS. BMC Cancer. 2014;14:139 pubmed publisher
An C, Ganio E, Hagiwara N. Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells. Skelet Muscle. 2013;3:11 pubmed publisher
Holmberg J, Ingner G, Johansson C, Leander P, Hjalt T. PITX2 gain-of-function induced defects in mouse forelimb development. BMC Dev Biol. 2008;8:25 pubmed publisher
image
image 1 :
Invitrogen MA5-11486 image 1
Human skeletal muscle myoblasts (hSMM) fixed in 3.7% formaldehyde and permeabilized with 0.2% Triton X-100 were stained with either Myogenin Monoclonal Antibody(Product # MA5-11486) at 1:10 dilution and an anti-mouse Texas Red secondary antibody (left) or secondary antibody alone (right). Nuclei were stained with DAPI (blue). Data courtesy of Innovators Program.
image 2 :
Invitrogen MA5-11486 image 2
Formalin-fixed, paraffin-embedded human rhabdomyosarcoma stained with Myogenin antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.
product information
Product Type :
Antibody
Product Name :
Myogenin Monoclonal Antibody (F5D)
Catalog # :
MA5-11486
Quantity :
500 µL
Pricing :
US 472
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Feline, Human, Mouse, Rat
Applications :
Gel Shift: 1mg/mL, Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1:400-1:800, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL
Species :
Feline, Human, Mouse, Rat
Clone :
F5D
Isotype :
IgG1, kappa
Storage :
4° C
Description :
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix proteins. It is essential for the development of functional skeletal muscle.
Immunogen :
Recombinant protein containing rat myogenin aa 30-224
Format :
Liquid
Applications w/Dilutions :
Gel Shift: 1mg/mL, Immunocytochemistry: 5 µg/mL, Immunohistochemistry (Paraffin): 1:400-1:800, Immunoprecipitation: 2 µg/mL, Western Blot: 1-2 µg/mL
Aliases :
bHLHc3; Class C basic helix-loop-helix protein 3; MYF4; Myf-4; myo; MYOD1-related protein; MYOG; Myogenic factor 4; Myogenic factor-4; myogenin; myogenin (myogenic factor 4)
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA