Thrombomodulin Monoclonal Antibody (141C01 (1009)) | Invitrogen MA5-11454 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Thrombomodulin Monoclonal Antibody (141C01 (1009))

catalog :

MA5-11454

quantity :

500 uL

price :

US 464.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

141C01 (1009)

reactivity :

human, rat

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; loading ...; fig 7i	Welsh J, Hoofnagle M, Bamezai S, Oxendine M, Lim L, Hall J, et al. Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis. J Clin Invest. 2019;129:5489-5500 pubmed publisher
immunohistochemistry; human; 1:25; fig 2	Arista Nasr J, Martinez Benitez B, Bornstein Quevedo L, Aguilar Ayala E, Aleman Sanchez C, Ortiz Bautista R. Low grade urothelial carcinoma mimicking basal cell hyperplasia and transitional metaplasia in needle prostate biopsy. Int Braz J Urol. 2016;42:247-52 pubmed publisher
immunohistochemistry; human	Trotman W, Taatjes D, Callas P, Bovill E. The endothelial microenvironment in the venous valvular sinus: thromboresistance trends and inter-individual variation. Histochem Cell Biol. 2011;135:141-52 pubmed publisher
immunocytochemistry; human	Campbell J, Brummel Ziedins K, Butenas S, Mann K. Cellular regulation of blood coagulation: a model for venous stasis. Blood. 2010;116:6082-91 pubmed publisher
immunohistochemistry; human	Tucker T, Dean C, Komissarov A, Koenig K, Mazar A, Pendurthi U, et al. The urokinase receptor supports tumorigenesis of human malignant pleural mesothelioma cells. Am J Respir Cell Mol Biol. 2010;42:685-96 pubmed publisher
immunohistochemistry; human	Brooks E, Trotman W, Wadsworth M, Taatjes D, Evans M, Ittleman F, et al. Valves of the deep venous system: an overlooked risk factor. Blood. 2009;114:1276-9 pubmed publisher
immunohistochemistry; rat	Zhang B, Liang X, Shi W, Ye Z, He C, Hu X, et al. Role of impaired peritubular capillary and hypoxia in progressive interstitial fibrosis after 56 subtotal nephrectomy of rats. Nephrology (Carlton). 2005;10:351-7 pubmed
	Melaiu O, Chierici M, Lucarini V, Jurman G, Conti L, De Vito R, et al. Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma. Nat Commun. 2020;11:5992 pubmed publisher
	Smith R, Ockleford C, Byrne S, Bosio P, Sanders R. Healthy and pre-eclamptic placental basal plate lining cells: quantitative comparisons based on confocal laser scanning microscopy. Microsc Res Tech. 2004;64:54-62 pubmed
	Ockleford C, Smith R, Byrne S, Sanders R, Bosio P. Confocal laser scanning microscope study of cytokeratin immunofluorescence differences between villous and extravillous trophoblast: cytokeratin downregulation in pre-eclampsia. Microsc Res Tech. 2004;64:43-53 pubmed
	Wurmser A, Nakashima K, Summers R, Toni N, D Amour K, Lie D, et al. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature. 2004;430:350-6 pubmed

product information

Product Type :

Antibody

Product Name :

Thrombomodulin Monoclonal Antibody (141C01 (1009))

Catalog # :

MA5-11454

Quantity :

500 uL

Price :

US 464.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Rat

Applications :

Flow Cytometry: 1:2, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:25-1:50

Species :

Human, Rat

Clone :

141C01 (1009)

Isotype :

IgG1, kappa

Storage :

4 C

Description :

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

Immunogen :

Recombinant protein encoding the six repeated EGF domains of human thrombomodulin

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2, Immunocytochemistry: 1:10-1:200, Immunohistochemistry (Paraffin): 1:25-1:50

Aliases :

AHUS6; AI385582; BDCA3; BDCA-3; CD141; CD141 antigen; DC141; fetomodulin; sCD141; snoRNA MBII-339; soluble CD141; THBD; THPH12; THRM; thrombomdulin; thrombomodulin; thrombomodulin precursor; TM

more info or order :

Invitrogen product webpage