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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
VCAM-1 Monoclonal Antibody (1.4C3)
catalog :
MA5-11447
quantity :
500 uL
price :
US 520.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1.4C3
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:100
Zeller I, Wiedemann D, Schwaiger S, Stelzmüller M, Kreutmayer S, Leberfing O, et al. Inhibition of cell surface expression of endothelial adhesion molecules by ursolic acid prevents intimal hyperplasia of venous bypass grafts in rats. Eur J Cardiothorac Surg. 2012;42:878-84 pubmed publisher
  • immunocytochemistry; human; 0.2 ug/ml
Schwaiger S, Zeller I, Pölzelbauer P, Frotschnig S, Laufer G, Messner B, et al. Identification and pharmacological characterization of the anti-inflammatory principal of the leaves of dwarf elder (Sambucus ebulus L.). J Ethnopharmacol. 2011;133:704-9 pubmed publisher
  • flow cytometry; human
Reisinger U, Schwaiger S, Zeller I, Messner B, Stigler R, Wiedemann D, et al. Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts. Cardiovasc Res. 2009;82:542-9 pubmed publisher
  • immunohistochemistry; human; 1:50
Florena A, Tripodo C, Porcasi R, Ingrao S, Fadda M, De Cantis S, et al. Immunophenotypic profile and role of adhesion molecules in splenic marginal zone lymphoma with bone marrow involvement. Leuk Lymphoma. 2006;47:49-57 pubmed
Lass xe9 M, El Saghir J, Berthier C, Eddy S, Fischer M, Laufer S, et al. An integrated organoid omics map extends modeling potential of kidney disease. Nat Commun. 2023;14:4903 pubmed publisher
Lake B, Menon R, Winfree S, Hu Q, Melo Ferreira R, Kalhor K, et al. An atlas of healthy and injured cell states and niches in the human kidney. Nature. 2023;619:585-594 pubmed publisher
Wen D, Hu L, Shan J, Zhang H, Hu L, Yuan A, et al. Mechanical injury accentuates lipid deposition in ApoE-/- mice and advance aortic valve stenosis: A novel modified aortic valve stenosis model. Front Cardiovasc Med. 2023;10:1119746 pubmed publisher
Manea S, Vlad M, Lazar A, Muresian H, Simionescu M, Manea A. Pharmacological Inhibition of Lysine-Specific Demethylase 1A Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Deficient Mice by a Mechanism Involving Decreased Oxidative Stress and Inflammation; Potential Implications in Human Atheroscler. Antioxidants (Basel). 2022;11: pubmed publisher
Voicu G, Rebleanu D, Mocanu C, Tanko G, Droc I, Uritu C, et al. VCAM-1 Targeted Lipopolyplexes as Vehicles for Efficient Delivery of shRNA-Runx2 to Osteoblast-Differentiated Valvular Interstitial Cells; Implications in Calcific Valve Disease Treatment. Int J Mol Sci. 2022;23: pubmed publisher
Gupta N, Matsumoto T, Hiratsuka K, Garcia Saiz E, Galichon P, Miyoshi T, et al. Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair. Sci Transl Med. 2022;14:eabj4772 pubmed publisher
Kij A, Bar A, Przyborowski K, Proniewski B, Mateuszuk L, Jasztal A, et al. Thrombin Inhibition Prevents Endothelial Dysfunction and Reverses 20-HETE Overproduction without Affecting Blood Pressure in Angiotensin II-Induced Hypertension in Mice. Int J Mol Sci. 2021;22: pubmed publisher
Bridges J, Sudha P, Lipps D, Wagner A, Guo M, Du Y, et al. Glucocorticoid regulates mesenchymal cell differentiation required for perinatal lung morphogenesis and function. Am J Physiol Lung Cell Mol Physiol. 2020;319:L239-L255 pubmed publisher
Martinez Sanchez J, Hamelmann H, Palomo M, Mir E, Moreno Castaño A, Torramade S, et al. Acute Graft-vs.-Host Disease-Associated Endothelial Activation in vitro Is Prevented by Defibrotide. Front Immunol. 2019;10:2339 pubmed publisher
Kulkarni N, Takahashi T, Sanford J, Tong Y, Gombart A, Hinds B, et al. Innate Immune Dysfunction in Rosacea Promotes Photosensitivity and Vascular Adhesion Molecule Expression. J Invest Dermatol. 2020;140:645-655.e6 pubmed publisher
Li X, Chen W, Li P, Wei J, Cheng Y, Liu P, et al. Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression. Theranostics. 2017;7:4671-4688 pubmed publisher
product information
Product Type :
Antibody
Product Name :
VCAM-1 Monoclonal Antibody (1.4C3)
Catalog # :
MA5-11447
Quantity :
500 uL
Price :
US 520.00
Clonality :
Monoclonal
Purity :
Protein A/G
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): 1:12.5-1:25, Immunohistochemistry (Paraffin): 1:12.5-1:25
Species :
Human, Mouse
Clone :
1.4C3
Isotype :
IgG1, kappa
Storage :
4 C
Description :
VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. The protein has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases.
Immunogen :
Stimulated human umbilical vein endothelial cells (HUVEC)
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Frozen): 1:12.5-1:25, Immunohistochemistry (Paraffin): 1:12.5-1:25
Aliases :
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA