Transferrin Receptor Monoclonal Antibody (10F11) | Invitrogen MA5-11441 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Transferrin Receptor Monoclonal Antibody (10F11)

catalog :

MA5-11441

quantity :

500 uL

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

10F11

reactivity :

hamsters, human, mouse, domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:200; fig 1	Geng J, Li J, Huang T, Zhao K, Chen Q, Guo W, et al. A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria. Mol Med Rep. 2016;14:1970-8 pubmed publisher
immunocytochemistry; human; 1:40; fig 5	Ooko E, Saeed M, Kadioglu O, Sarvi S, Colak M, Elmasaoudi K, et al. Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells. Phytomedicine. 2015;22:1045-54 pubmed publisher
immunocytochemistry; hamsters	Miorin L, Maiuri P, Hoenninger V, Mandl C, Marcello A. Spatial and temporal organization of tick-borne encephalitis flavivirus replicated RNA in living cells. Virology. 2008;379:64-77 pubmed publisher
immunocytochemistry; domestic sheep	Islam M, Zhou H. Isolation and characterization of putative epidermal stem cells derived from Cashmere goat fetus. Eur J Dermatol. 2007;17:302-8 pubmed
	Liu D, Pahar B, Perry D, Xu H, Cooper T, Huzella L, et al. Depletion of Bone Marrow Hematopoietic Cells in Ebolavirus-Infected Rhesus Macaques: A Possible Cause of Hematologic Abnormalities in Ebolavirus Disease. Am J Pathol. 2023;193:2031-2046 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Transferrin Receptor Monoclonal Antibody (10F11)

Catalog # :

MA5-11441

Quantity :

500 uL

Price :

US 524.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:20-1:40, Western Blot: 1:100-1:500

Species :

Human, Mouse

Clone :

10F11

Isotype :

IgG2b

Storage :

4 C

Description :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:20-1:40, Western Blot: 1:100-1:500

Aliases :

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

more info or order :

Invitrogen product webpage