hCG beta Antibody Cocktail | Invitrogen MA5-11324 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

hCG beta Antibody Cocktail

catalog :

MA5-11324

quantity :

500 µL

price :

US 389.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CG04, CG05

reactivity :

human, rhesus macaque

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:100 western blot; human; 1:2000	Chang E, Lee E, Oh S, Kim J, Kang C. The immunoexpressions and prognostic significance of inhibin alpha and beta human chorionic gonadotrophins (HCG) in breast carcinomas. Cancer Res Treat. 2005;37:241-6 pubmed publisher
immunohistochemistry; rhesus macaque	Marbaix E, Defrere S, Duc K, Lousse J, Dehoux J. Non-gestational malignant placental site trophoblastic tumor of the ovary in a 4-year-old rhesus monkey. Vet Pathol. 2008;45:375-8 pubmed publisher
immunohistochemistry; human	Russell M, Flynt F, Harroff A, Fadare O. Dedifferentiated Liposarcoma of the Retroperitoneum with Extensive Leiomyosarcomatous Differentiation and beta-Human Chorionic Gonadotropin Production. Sarcoma. 2008;2008:658090 pubmed publisher
immunocytochemistry; human	Petroff M, Phillips T, Ka H, Pace J, Hunt J. Isolation and culture of term human trophoblast cells. Methods Mol Med. 2006;121:203-17 pubmed
immunocytochemistry; human	Ka H, Hunt J. FLICE-inhibitory protein: expression in early and late gestation human placentas. Placenta. 2006;27:626-34 pubmed
	Ka H, Hunt J. Temporal and spatial patterns of expression of inhibitors of apoptosis in human placentas. Am J Pathol. 2003;163:413-22 pubmed
	Gill R, Ni J, Hunt J. Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes. Am J Pathol. 2002;161:2011-7 pubmed

product information

Product Type :

Antibody

Product Name :

hCG beta Antibody Cocktail

Catalog # :

MA5-11324

Quantity :

500 µL

Price :

US 389.00

Clonality :

Cocktail

Purity :

Protein A/G

Host :

Mouse

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1-2 µg/mL

Species :

Human

Clone :

CG04, CG05

Isotype :

IgG1, kappa/IgG2a, kappa

Storage :

4° C

Description :

hCG beta is the beta chain of hCG (Human chorionic gonadotropin), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. hCG is made up of alpha and beta subunits that are non-covalently associated. The alpha subunit is similar to those found on the pituitary hormones FSH, LH ans TSH. However, the beta subunit is different in FSH, LH and TSH and are involved in conferring biological specificity. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and Beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). Diseases associated with Hcg dysfunction include gestational trophoblastic tumor and hydatidiform mole, recurrent 1.

Immunogen :

Purified beta-subunit of HCG

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1-2 µg/mL

Aliases :

CGB; CGB3; CGB5; CGB7; CGB8; CG-beta; Choriogonadotropin subunit beta; choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit; chorionic gonadotropin beta subunit 3; chorionic gonadotropin chain beta; chorionic gonadotropin human; chorionic gonadotropin, beta polypeptide; FSH-alpha; hCGB; human chorionic gonadotropin; LSH-alpha; TSH-alpha