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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
p57 Kip2 Monoclonal Antibody (57P06 (KP10))
catalog :
MA5-11309
quantity :
500 uL
price :
US 480.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
57P06 (KP10)
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:100
Stolnicu S, Ilyes A, Quiñonez E, Nogales F. Ectopic Complete Hydatidiform Mole Presenting as an Adnexal Tumor in a Postmenopausal Patient. Int J Surg Pathol. 2014;22:470-2 pubmed publisher
  • immunohistochemistry; human; 1:700
Furtado L, Paxton C, Jama M, Tripp S, Wilson A, Lyon E, et al. Diagnostic utility of microsatellite genotyping for molar pregnancy testing. Arch Pathol Lab Med. 2013;137:55-63 pubmed publisher
  • immunohistochemistry; human
Osterheld M, Caron L, Chaubert P, Meagher Villemure K. Combination of immunohistochemistry and ploidy analysis to assist histopathological diagnosis of molar diseases. Clin Med Pathol. 2008;1:61-7 pubmed
  • western blot; mouse
Tury A, Mairet Coello G, Dicicco Bloom E. The cyclin-dependent kinase inhibitor p57Kip2 regulates cell cycle exit, differentiation, and migration of embryonic cerebral cortical precursors. Cereb Cortex. 2011;21:1840-56 pubmed publisher
  • immunohistochemistry; human; 1:400
Wurz K, Garcia R, Goff B, Mitchell P, Lee J, Tewari M, et al. MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B, CDKNIC and overall survival. Genes Chromosomes Cancer. 2010;49:577-84 pubmed publisher
  • immunohistochemistry; human; 1:4000
Dube V, Chun K, Osborne R, Sherman C, Nofech Mozes S, Ismiil N, et al. Androgenetic complete mole with trisomy 13: report of a case with microsatellite genotyping and review of the literature. Pathol Res Pract. 2010;206:776-81 pubmed publisher
  • immunohistochemistry; human; 1:600
Paul M, Goodman S, Felix J, Lewis R, Hawkins M, Drey E. Early molar pregnancy: experience in a large abortion service. Contraception. 2010;81:150-6 pubmed publisher
  • immunohistochemistry; human; 1:1000
Kipp B, Ketterling R, Oberg T, Cousin M, Plagge A, Wiktor A, et al. Comparison of fluorescence in situ hybridization, p57 immunostaining, flow cytometry, and digital image analysis for diagnosing molar and nonmolar products of conception. Am J Clin Pathol. 2010;133:196-204 pubmed publisher
  • immunohistochemistry; human; 1:500
Kim K, Park B, Hong Y, Kwon H, Robboy S. The villous stromal constituents of complete hydatidiform mole differ histologically in very early pregnancy from the normally developing placenta. Am J Surg Pathol. 2009;33:176-85 pubmed publisher
  • immunohistochemistry; mouse; 1:100
El Bizri N, Guignabert C, Wang L, Cheng A, Stankunas K, Chang C, et al. SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. Development. 2008;135:2981-91 pubmed publisher
  • immunohistochemistry; human
Osterheld M, Caron L, Meagher Villemure K. Role of DNA content analysis and immunohistochemistry in the evaluation of the risk of unfavourable outcome in Wilms' tumours. Anticancer Res. 2008;28:751-6 pubmed
  • immunohistochemistry; human
Hoffner L, Dunn J, Esposito N, Macpherson T, Surti U. P57KIP2 immunostaining and molecular cytogenetics: combined approach aids in diagnosis of morphologically challenging cases with molar phenotype and in detecting androgenetic cell lines in mosaic/chimeric conceptions. Hum Pathol. 2008;39:63-72 pubmed
  • immunohistochemistry; human; 1:50
Melck A, Masoudi H, Griffith O, Rajput A, Wilkins G, Bugis S, et al. Cell cycle regulators show diagnostic and prognostic utility for differentiated thyroid cancer. Ann Surg Oncol. 2007;14:3403-11 pubmed
  • immunohistochemistry; human
Popiolek D, Yee H, Mittal K, Chiriboga L, Prinz M, Caragine T, et al. Multiplex short tandem repeat DNA analysis confirms the accuracy of p57(KIP2) immunostaining in the diagnosis of complete hydatidiform mole. Hum Pathol. 2006;37:1426-34 pubmed
  • immunohistochemistry; human; fig 8
Kuusniemi A, Merenmies J, Lahdenkari A, Holmberg C, Salmela K, Karikoski R, et al. Glomerular sclerosis in kidneys with congenital nephrotic syndrome (NPHS1). Kidney Int. 2006;70:1423-31 pubmed
  • immunohistochemistry; mouse; 1:67
Rothschild G, Zhao X, Iavarone A, Lasorella A. E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells. Mol Cell Biol. 2006;26:4351-61 pubmed
  • immunohistochemistry; human; 1:500
Kim M, Kim K, Ro J, Lage J, Lee H. Diagnostic and pathogenetic significance of increased stromal apoptosis and incomplete vasculogenesis in complete hydatidiform moles in very early pregnancy periods. Am J Surg Pathol. 2006;30:362-9 pubmed
  • immunohistochemistry; human
Suchi M, MacMullen C, Thornton P, Adzick N, Ganguly A, Ruchelli E, et al. Molecular and immunohistochemical analyses of the focal form of congenital hyperinsulinism. Mod Pathol. 2006;19:122-9 pubmed
  • immunohistochemistry; human
Sato N, Matsubayashi H, Abe T, Fukushima N, Goggins M. Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling. Clin Cancer Res. 2005;11:4681-8 pubmed
  • immunohistochemistry; human; 1:200
Merchant S, Amin M, Viswanatha D, Malhotra R, Moehlenkamp C, Joste N. p57KIP2 immunohistochemistry in early molar pregnancies: emphasis on its complementary role in the differential diagnosis of hydropic abortuses. Hum Pathol. 2005;36:180-6 pubmed
Szabolcsi Z, Demeter A, Kiraly P, Balogh A, Wilson M, King J, et al. Epigenetic Dysregulation of Trophoblastic Gene Expression in Gestational Trophoblastic Disease. Biomedicines. 2021;9: pubmed publisher
King J, Wilson M, Hetey S, Kiraly P, Matsuo K, Castaneda A, et al. Dysregulation of Placental Functions and Immune Pathways in Complete Hydatidiform Moles. Int J Mol Sci. 2019;20: pubmed publisher
Sebire N, Rees H, Peston D, Seckl M, Newlands E, Fisher R. p57(KIP2) immunohistochemical staining of gestational trophoblastic tumours does not identify the type of the causative pregnancy. Histopathology. 2004;45:135-41 pubmed
Qiu L, Sinniah R, I Hong Hsu S. Downregulation of Bcl-2 by podocytes is associated with progressive glomerular injury and clinical indices of poor renal prognosis in human IgA nephropathy. J Am Soc Nephrol. 2004;15:79-90 pubmed
Jun S, Ro J, Kim K. p57kip2 is useful in the classification and differential diagnosis of complete and partial hydatidiform moles. Histopathology. 2003;43:17-25 pubmed
product information
Product Type :
Antibody
Product Name :
p57 Kip2 Monoclonal Antibody (57P06 (KP10))
Catalog # :
MA5-11309
Quantity :
500 uL
Price :
US 480.00
Clonality :
Monoclonal
Purity :
protein A
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Immunohistochemistry (Paraffin): 1:200-1:800, Western Blot: 1:50-1:500
Species :
Human, Mouse
Clone :
57P06 (KP10)
Isotype :
IgG2b, kappa
Storage :
4 C
Description :
This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
Immunogen :
Recombinant human p57Kip2 protein
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:200-1:800, Western Blot: 1:50-1:500
Aliases :
AL024410; Beckwith Wiedemann syndrome (WBS); BWCR; BWS; CDKI; Cdkn1c; cyclin dependent kinase inhibitor 1C; Cyclin dependent kinase inhibitor 1C (CDKN1C); cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (P57); cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; IMAGE; KIP2; p57; p57 Kip2; p57(kip2); p57KIP2; p57KIP2 A3sh; WBS
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA