CDK5 Antibody Cocktail | Invitrogen MA5-11291 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CDK5 Antibody Cocktail

catalog :

MA5-11291

quantity :

500 µL

price :

US 496.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DC17, DC34

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:5000	Ramos Miguel A, Meana J, Garcia Sevilla J. Cyclin-dependent kinase-5 and p35/p25 activators in schizophrenia and major depression prefrontal cortex: basal contents and effects of psychotropic medications. Int J Neuropsychopharmacol. 2013;16:683-9 pubmed publisher
immunocytochemistry; mouse; 1:400 western blot; mouse; 1:1000	Shi L, Yang W, Chen X, Zhang J, Yang P, Hu X, et al. The protective effects of tanshinone IIA on neurotoxicity induced by ?-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons. Neurochem Int. 2012;61:227-35 pubmed publisher
western blot; rat	Ramos Miguel A, García Sevilla J. Crosstalk between cdk5 and MEK-ERK signalling upon opioid receptor stimulation leads to upregulation of activator p25 and MEK1 inhibition in rat brain. Neuroscience. 2012;215:17-30 pubmed publisher
immunocytochemistry; rat; 1:400 western blot; rat; 1:1000	Jordà E, Verdaguer E, Canudas A, Jimenez A, Garcia De Arriba S, Allgaier C, et al. Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium. Neuroscience. 2005;134:1001-11 pubmed
	Jordà E, Verdaguer E, Jimenez A, Canudas A, Rimbau V, Camps P, et al. (+/-)-huprine Y, (-)-huperzine A and tacrine do not show neuroprotective properties in an apoptotic model of neuronal cytoskeletal alteration. J Alzheimers Dis. 2004;6:577-83; discussion 673-81 pubmed

product information

Product Type :

Antibody

Product Name :

CDK5 Antibody Cocktail

Catalog # :

MA5-11291

Quantity :

500 µL

Price :

US 496.00

Clonality :

Cocktail

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: Assay-dependent, Immunoprecipitation: 6 µg/mg protein lysate, Western Blot: 1-2 µg/mL

Species :

Human, Mouse, Rat

Clone :

DC17, DC34

Isotype :

IgG1

Storage :

4° C

Description :

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.

Immunogen :

Recombinant cdk5 protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunoprecipitation: 6 µg/mg protein lysate, Western Blot: 1-2 µg/mL

Aliases :

AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit