HSP27 Monoclonal Antibody (G3.1), Biotin | Invitrogen MA5-11213 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HSP27 Monoclonal Antibody (G3.1), Biotin

catalog :

MA5-11213

quantity :

500µL

price :

US 375.00

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

G3.1

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 17

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human	Carter C. Multiplexed high content screening reveals that cigarette smoke condensate-altered cell signaling pathways are accentuated through FAK inhibition in human bronchial cells. Int J Toxicol. 2012;31:257-66 pubmed publisher
immunohistochemistry; human; 1:400	Rantanen T, Honkanen T, Paavonen T, Rantanen L, Oksala N. Altered expression of HSP27 and HSP70 in distal oesophageal mucosa in patients with gastro-oesophageal reflux disease subjected to fundoplication. Eur J Surg Oncol. 2011;37:168-74 pubmed publisher
immunohistochemistry; human	Ozger H, Eralp L, Atalar A, Toker B, Esberk Ateş L, Sungur M, et al. [The effect of resistance-related proteins on the prognosis and survival of patients with osteosarcoma: an immunohistochemical analysis]. Acta Orthop Traumatol Turc. 2009;43:28-34 pubmed publisher
western blot; human	Liu Y, Liu H, Han B, Zhang J. Identification of 14-3-3sigma as a contributor to drug resistance in human breast cancer cells using functional proteomic analysis. Cancer Res. 2006;66:3248-55 pubmed
western blot; human	Sommer S, Cui Y, Brewer G, Fuqua S. The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells. J Steroid Biochem Mol Biol. 2005;97:219-29 pubmed
immunohistochemistry; human; 1:50	Joo M, Chi J, Lee H. Expressions of HSP70 and HSP27 in hepatocellular carcinoma. J Korean Med Sci. 2005;20:829-34 pubmed
western blot; human	Caraglia M, Marra M, Mancinelli F, d Ambrosio G, Massa R, Giordano A, et al. Electromagnetic fields at mobile phone frequency induce apoptosis and inactivation of the multi-chaperone complex in human epidermoid cancer cells. J Cell Physiol. 2005;204:539-48 pubmed
	Wen F, Li Y, Tsai H, Lin C, Li C, Liu C, et al. Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3. FEBS Lett. 2003;546:307-14 pubmed
	Elpek G, Karaveli S, Simsek T, Keles N, Aksoy N. Expression of heat-shock proteins hsp27, hsp70 and hsp90 in malignant epithelial tumour of the ovaries. APMIS. 2003;111:523-30 pubmed
	Pignatelli D, Ferreira J, Soares P, Costa M, Magalhães M. Immunohistochemical study of heat shock proteins 27, 60 and 70 in the normal human adrenal and in adrenal tumors with suppressed ACTH production. Microsc Res Tech. 2003;61:315-23 pubmed
	Benvenuti S, Cramer R, Quinn C, Bruce J, Zvelebil M, Corless S, et al. Differential proteome analysis of replicative senescence in rat embryo fibroblasts. Mol Cell Proteomics. 2002;1:280-92 pubmed
	Wyttenbach A, Sauvageot O, Carmichael J, Diaz Latoud C, Arrigo A, Rubinsztein D. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. Hum Mol Genet. 2002;11:1137-51 pubmed
	Wyttenbach A, Swartz J, Kita H, Thykjaer T, Carmichael J, Bradley J, et al. Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum Mol Genet. 2001;10:1829-45 pubmed
	Gerner C, Frohwein U, Gotzmann J, Bayer E, Gelbmann D, Bursch W, et al. The Fas-induced apoptosis analyzed by high throughput proteome analysis. J Biol Chem. 2000;275:39018-26 pubmed
	Soldes O, Kuick R, Thompson I, Hughes S, Orringer M, Iannettoni M, et al. Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas. Br J Cancer. 1999;79:595-603 pubmed
	Ciocca D, Green S, Elledge R, Clark G, Pugh R, Ravdin P, et al. Heat shock proteins hsp27 and hsp70: lack of correlation with response to tamoxifen and clinical course of disease in estrogen receptor-positive metastatic breast cancer (a Southwest Oncology Group Study). Clin Cancer Res. 1998;4:1263-6 pubmed
	Ito T, Kawabe R, Kurasono Y, Hara M, Kitamura H, Fujita K, et al. Expression of heat shock proteins in squamous cell carcinoma of the tongue: an immunohistochemical study. J Oral Pathol Med. 1998;27:18-22 pubmed

product information

Product Type :

Antibody

Product Name :

HSP27 Monoclonal Antibody (G3.1), Biotin

Catalog # :

MA5-11213

Quantity :

500µL

Price :

US 375.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Immunohistochemistry (Paraffin): 1-2 µg/ml, Western Blot: 1-2 µg/ml

Species :

Human, Non-human primate

Clone :

G3.1

Isotype :

IgG1

Storage :

4° C

Description :

Hsp27 is identical to the estrogen-induced "p29" and "24K" protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.

Immunogen :

Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1-2 µg/ml, Western Blot: 1-2 µg/ml

Aliases :

Heat shock protein beta-1; HspB1; HSP25; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27; Estrogen-regulated 24 kDa protein; 28 kDa heat shock protein; HSPB1; HSP27