SUZ12 Monoclonal Antibody (K.6.9) | Invitrogen MA5-11188 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SUZ12 Monoclonal Antibody (K.6.9)

catalog :

MA5-11188

quantity :

100 µL

price :

US 446.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

K.6.9

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat	Yildiz C, Kacan T, Akkar O, Karakus S, Kacan S, Ozer H, et al. Effects of Pazopanib, Sunitinib, and Sorafenib, Anti-VEGF Agents, on the Growth of Experimental Endometriosis in Rats. Reprod Sci. 2015;22:1445-51 pubmed publisher
	Huang H, Chao C, Wu P, Chung H, Lee H, Suen C, et al. Epigenetic silencing of the synthesis of immunosuppressive Siglec ligand glycans by NF-κB/EZH2/YY1 axis in early-stage colon cancers. Biochim Biophys Acta Gene Regul Mech. 2019;1862:173-183 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SUZ12 Monoclonal Antibody (K.6.9)

Catalog # :

MA5-11188

Quantity :

100 µL

Price :

US 446.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

ChIP Assay: 1:100, Immunocytochemistry: 1:800, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Species :

Human, Mouse, Non-human primate, Rat

Clone :

K.6.9

Isotype :

IgG

Storage :

-20°C

Description :

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

Immunogen :

Synthetic peptide corresponding to the sequence of the human SUZ12 protein

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1:100, Immunocytochemistry: 1:800, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Aliases :

2610028O16Rik; AI195385; AU016842; AW536442; chET 9 protein; CHET9; chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; Kiaa0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog; suppressor of zeste 12 homolog (Drosophila); suppressor of zeste 12 protein homolog; Suz12; SUZ12 polycomb repressive complex 2 subunit

more info or order :

Invitrogen product webpage