RASA1 Monoclonal Antibody (B4F8) | Invitrogen MA4-001 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RASA1 Monoclonal Antibody (B4F8)

catalog :

MA4-001

quantity :

100µg

price :

US 390

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

B4F8

reactivity :

human, mouse, rat, bovine

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; loading ...; fig 2k	Shapiro L, Parsons R, Koleske A, Gourley S. Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development. J Neurosci Res. 2017;95:1123-1143 pubmed publisher
immunoprecipitation; mouse; 1 ug/mL western blot; mouse	Kerrisk M, Greer C, Koleske A. Integrin ?3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior. J Neurosci. 2013;33:6742-52 pubmed publisher
	Settleman J, Narasimhan V, Foster L, Weinberg R. Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus. Cell. 1992;69:539-49 pubmed

product information

Product Type :

Antibody

Product Name :

RASA1 Monoclonal Antibody (B4F8)

Catalog # :

MA4-001

Quantity :

100µg

Price :

US 390

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Bovine, Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunoprecipitation: 1-5 µg, Western Blot: 10 µg/mL

Species :

Bovine, Human, Mouse, Non-human primate, Rat

Clone :

B4F8

Isotype :

IgG2a

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.

Immunogen :

Full length recombinant human GAP.

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunoprecipitation: 1-5 µg, Western Blot: 10 µg/mL

Aliases :

BOS_8464; CMAVM; CM-AVM; GAP; GAPX; GTPase-activating protein; p120; p120 RAS GTPase activating protein; p120GAP; p120RASGAP; p120-rasGAP; PKWS; Ras GTPase-activating protein 1; Ras p21 protein activator; RAS p21 protein activator (GTPase activating protein RAS p21); RAS p21 protein activator (GTPase activating protein) 1; RAS p21 protein activator 1; RASA; Rasa1; RASGAP; triphosphatase-activating protein

more info or order :

Invitrogen product webpage