Calpastatin Monoclonal Antibody (2G11D6) | Invitrogen MA3-945 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Calpastatin Monoclonal Antibody (2G11D6)

catalog :

MA3-945

quantity :

100 µL

price :

US 399.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2G11D6

reactivity :

rainbow trout, human, mouse, rat, dogs, bovine, pigs , domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; bovine; 1:5000	Cruzen S, Paulino P, Lonergan S, Huff Lonergan E. Postmortem proteolysis in three muscles from growing and mature beef cattle. Meat Sci. 2014;96:854-61 pubmed publisher
western blot; bovine; 1:2,000	Camou J, Mares S, Marchello J, Vazquez R, Taylor M, Thompson V, et al. Isolation and characterization of mu-calpain, m-calpain, and calpastatin from postmortem muscle. I. Initial steps. J Anim Sci. 2007;85:3400-14 pubmed
western blot; rainbow trout	Saito M, Li H, Thompson V, Kunisaki N, Goll D. Purification and characterization of calpain and calpastatin from rainbow trout, Oncorhynchus mykiss. Comp Biochem Physiol B Biochem Mol Biol. 2007;146:445-55 pubmed
immunohistochemistry; mouse; 1:1000 western blot; mouse; 1:10000	Paquet Durand F, Azadi S, Hauck S, Ueffing M, van Veen T, Ekstrom P. Calpain is activated in degenerating photoreceptors in the rd1 mouse. J Neurochem. 2006;96:802-14 pubmed
	Curry S, Burrough E, Schwartz K, Yoon K, Lonergan S, Gabler N. Porcine epidemic diarrhea virus reduces feed efficiency in nursery pigs. J Anim Sci. 2018;96:85-97 pubmed publisher
	Du M, Zhu M, Means W, Hess B, Ford S. Effect of nutrient restriction on calpain and calpastatin content of skeletal muscle from cows and fetuses. J Anim Sci. 2004;82:2541-7 pubmed
	Helman E, Huff Lonergan E, Davenport G, Lonergan S. Effect of dietary protein on calpastatin in canine skeletal muscle. J Anim Sci. 2003;81:2199-205 pubmed
	Gil Parrado S, Popp O, Knoch T, Zahler S, Bestvater F, Felgenträger M, et al. Subcellular localization and in vivo subunit interactions of ubiquitous mu-calpain. J Biol Chem. 2003;278:16336-46 pubmed
	Sultan K, Dittrich B, Leisner E, Paul N, Pette D. Fiber type-specific expression of major proteolytic systems in fast- to slow-transforming rabbit muscle. Am J Physiol Cell Physiol. 2001;280:C239-47 pubmed
	Lane R, Allan D, Mellgren R. A comparison of the intracellular distribution of mu-calpain, m-calpain, and calpastatin in proliferating human A431 cells. Exp Cell Res. 1992;203:5-16 pubmed

product information

Product Type :

Antibody

Product Name :

Calpastatin Monoclonal Antibody (2G11D6)

Catalog # :

MA3-945

Quantity :

100 µL

Price :

US 399.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Bovine, Canine, Human, Porcine, Rabbit, Rat

Applications :

Immunocytochemistry: 1:1,000, Immunohistochemistry (Frozen): 1:200-1:1,000, Western Blot: 1:5,000

Species :

Bovine, Canine, Human, Porcine, Rabbit, Rat

Clone :

2G11D6

Isotype :

IgG2a

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Calpastatin is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins.

Immunogen :

Bovine skeletal muscle calpastatin.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:1,000, Immunohistochemistry (Frozen): 1:200-1:1,000, Western Blot: 1:5,000

Aliases :

BS-17; Calpain inhibitor; calpastatin; calpastatin isoform III; calpastatin precursor (EC 3.4.22.17); calpastatin type 1; calpastatin type 2; calpastatin type 3; calpastatin type I; calpastatin type II; calpastatin type III; calpastatin type IV; Cast; Erythrocyte calpastatin; heart calpastatin; PLACK; Sperm BS-17 component; type III calpastatin

more info or order :

Invitrogen product webpage