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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
JSRP1 Monoclonal Antibody (VF1c)
catalog :
MA3-933
quantity :
100µL
price :
US 390
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VF1C
reactivity :
guinea pig, mouse, rat, dogs, pigs
application :
western blot, immunocytochemistry
more info or order :
citations: 6
| Published Application/Species/Sample/Dilution | Reference |
|---|---|
| Schulz J, Palmer N, Steckelberg J, Jones S, Zeece M. Microarray profiling of skeletal muscle sarcoplasmic reticulum proteins. Biochim Biophys Acta. 2006;1764:1429-35 pubmed
|
O Reilly C, Pette D, Ohlendieck K. Increased expression of the nicotinic acetylcholine receptor in stimulated muscle. Biochem Biophys Res Commun. 2003;300:585-91 pubmed
| |
Zorzato F, Anderson A, Ohlendieck K, Froemming G, Guerrini R, Treves S. Identification of a novel 45 kDa protein (JP-45) from rabbit sarcoplasmic-reticulum junctional-face membrane. Biochem J. 2000;351 Pt 2:537-43 pubmed
| |
Froemming G, Murray B, Harmon S, Pette D, Ohlendieck K. Comparative analysis of the isoform expression pattern of Ca(2+)-regulatory membrane proteins in fast-twitch, slow-twitch, cardiac, neonatal and chronic low-frequency stimulated muscle fibers. Biochim Biophys Acta. 2000;1466:151-68 pubmed
| |
Guo W, Jorgensen A, Campbell K. Characterization and ultrastructural localization of a novel 90-kDa protein unique to skeletal muscle junctional sarcoplasmic reticulum. J Biol Chem. 1994;269:28359-65 pubmed
| |
Campbell K, Knudson C, Imagawa T, Leung A, Sutko J, Kahl S, et al. Identification and characterization of the high affinity [3H]ryanodine receptor of the junctional sarcoplasmic reticulum Ca2+ release channel. J Biol Chem. 1987;262:6460-3 pubmed
|
product information
Product Type :
Antibody
Product Name :
JSRP1 Monoclonal Antibody (VF1c)
Catalog # :
MA3-933
Quantity :
100µL
Price :
US 390
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Canine, Guinea Pig, Mouse, Rabbit, Rat
Applications :
Immunofluorescence: 1:250, Western Blot: 1:1,500
Species :
Canine, Guinea Pig, Mouse, Rabbit, Rat
Clone :
VF1c
Isotype :
IgG1
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR and RyR. Another skeletal muscle specific 90 kDa protein has also been localized to the this junction. This protein is phosphorylated by an intrinsic protein kinase in triads suggesting that it may play an important regulatory or structural role in the skeletal muscle triad junction.
Immunogen :
Rabbit skeletal muscle triads.
Format :
Liquid
Applications w/Dilutions :
Immunofluorescence: 1:250, Western Blot: 1:1,500
Aliases :
2300003C06Rik; 2310032K21Rik; homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45; JP45; JP-45; JSRP1; Junctional sarcoplasmic reticulum protein 1; Junctional SR; Junctional-face membrane protein of 45 kDa homolog; skeletal muscle sarcoplasmic reticulum protein JP-45
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA