HCN4 Monoclonal Antibody (SHG 1E5) | Invitrogen MA3-903 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HCN4 Monoclonal Antibody (SHG 1E5)

catalog :

MA3-903

quantity :

100 µL

price :

US 399.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

SHG 1E5

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:2000	Cain S, Tyson J, Jones K, Snutch T. Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy. Pflugers Arch. 2015;467:1367-82 pubmed publisher
	Muller F, Scholten A, Ivanova E, Haverkamp S, Kremmer E, Kaupp U. HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals. Eur J Neurosci. 2003;17:2084-96 pubmed
	Stevens D, Seifert R, Bufe B, Muller F, Kremmer E, Gauss R, et al. Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli. Nature. 2001;413:631-5 pubmed

product information

Product Type :

Antibody

Product Name :

HCN4 Monoclonal Antibody (SHG 1E5)

Catalog # :

MA3-903

Quantity :

100 µL

Price :

US 399.00

Clonality :

Monoclonal

Host :

Rat

Reactivity :

Human, Mouse, Rat

Applications :

Flow Cytometry: 1/50, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:5,000

Species :

Human, Mouse, Rat

Clone :

SHG 1E5

Isotype :

IgG1

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

HCN4 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node.

Immunogen :

Synthetic peptide sequence corresponding to residues S H G S L L L P P A S S P P P P Q V P Q R R G T P P L T P G R L T Q D L K L of HCN4.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1/50, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:5,000

Aliases :

Bcng3; BCNG-3; brain cyclic nucleotide-gated channel 3; Hcn3; Hcn4; hyperpolarization activated cyclic nucleotide gated potassium channel 4; hyperpolarization activated cyclic nucleotide-gated cation channel 4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; hyperpolarization-activated, cyclic nucleotide-gated K+ 3; hyperpolarization-activated, cyclic nucleotide-gated K+ 4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; SSS2

more info or order :

Invitrogen product webpage