CRMP5 Monoclonal Antibody (CR-3) | Invitrogen MA3-700 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CRMP5 Monoclonal Antibody (CR-3)

catalog :

MA3-700

quantity :

100 uL

price :

US 451.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

CR-3

The same clone is also sold as:

Santa Cruz Biotechnology: sc-58516

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 2

Reference
Kaarij xe4 rvi R, Kaljunen H, Nappi L, Fazli L, Kung S, Hartikainen J, et al. DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2. Commun Biol. 2024;7:108 pubmed publisher
Cross S, Salomao D, Parisi J, Kryzer T, Bradley E, Mines J, et al. Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG. Ann Neurol. 2003;54:38-50 pubmed

product information

Product Type :

Antibody

Product Name :

CRMP5 Monoclonal Antibody (CR-3)

Catalog # :

MA3-700

Quantity :

100 uL

Price :

US 451.00

Clonality :

Monoclonal

Host :

Rat

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:50 - 1:400, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:50-1:1,000

Species :

Bovine, Human, Mouse, Rat

Clone :

CR-3

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

Immunogen :

CRMP5 protein purified from human brain.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:50 - 1:400, Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:50-1:1,000

Aliases :

collapsin response mediator protein 5; collapsin response mediator protein-5; CRAM; CRMP3-associated molecule; Crmp5; CRMP-5; dihydropyrimidinase like 5; dihydropyrimidinase-like 5; dihydropyrimidinase-related protein 5; Dpysl5; DRP-5; Ulip6; ULIP-6; ULIP6 protein; UNC33-like phosphoprotein 6