product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Caveolin 1 Monoclonal Antibody (7C8)
catalog :
MA3-600
quantity :
100 µL
price :
US 375.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7C8
reactivity :
Chinese hamsters, human, mouse, rat, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; pigs ; 1:200; loading ...; tbl 5
Démoulins T, Englezou P, Milona P, Ruggli N, Tirelli N, Pichon C, et al. Self-Replicating RNA Vaccine Delivery to Dendritic Cells. Methods Mol Biol. 2017;1499:37-75 pubmed
  • western blot; mouse; fig 2
Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed publisher
  • western blot; rat
Kaakinen M, Zelenin S, Metsikkö K. Aquaporin-4 water channel oligomers are associated with the transverse tubules of skeletal myofibers. Exp Cell Res. 2011;317:20-8 pubmed publisher
Li Y, Hu H, O Neil R. Caveolae facilitate TRPV4-mediated Ca2+ signaling and the hierarchical activation of Ca2+-activated K+ channels in K+-secreting renal collecting duct cells. Am J Physiol Renal Physiol. 2018;315:F1626-F1636 pubmed publisher
Knopf J, Tholen S, Koczorowska M, De Wever O, Biniossek M, Schilling O. The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia. Biochim Biophys Acta. 2015;1853:2515-25 pubmed publisher
Souto R, Vallega G, Wharton J, Vinten J, Tranum Jensen J, Pilch P. Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling. J Biol Chem. 2003;278:18321-9 pubmed
image
image 1 :
Invitrogen MA3-600 image 1
Immunofluorescent analysis of Caveolin 1 in H-4-II-E Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a Caveolin 1 monoclonal antibody (Product # MA3-600) at a dilution of 1:200 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product # 35503). Caveolin 1 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.
product information
Product Type :
Antibody
Product Name :
Caveolin 1 Monoclonal Antibody (7C8)
Catalog # :
MA3-600
Quantity :
100 µL
Price :
US 375.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Hamster, Human, Rat
Applications :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:125, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 1-3 µL, Western Blot: 1:200-1:2,000
Species :
Hamster, Human, Rat
Clone :
7C8
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
Immunogen :
Intercellular membrane protein-containing vesicles (containing GLUT4) from rat.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:125, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 1-3 µL, Western Blot: 1:200-1:2,000
Aliases :
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA