Caveolin 1 Monoclonal Antibody (7C8) | Invitrogen MA3-600 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Caveolin 1 Monoclonal Antibody (7C8)

catalog :

MA3-600

quantity :

100 µL

price :

US 375.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7C8

reactivity :

Chinese hamsters, human, mouse, rat, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; pigs ; 1:200; loading ...; tbl 5	DÃ©moulins T, Englezou P, Milona P, Ruggli N, Tirelli N, Pichon C, et al. Self-Replicating RNA Vaccine Delivery to Dendritic Cells. Methods Mol Biol. 2017;1499:37-75 pubmed
western blot; mouse; fig 2	Cizmecioglu O, Ni J, Xie S, Zhao J, Roberts T. Rac1-mediated membrane raft localization of PI3K/p110? is required for its activation by GPCRs or PTEN loss. elife. 2016;5: pubmed publisher
western blot; rat	Kaakinen M, Zelenin S, Metsikkö K. Aquaporin-4 water channel oligomers are associated with the transverse tubules of skeletal myofibers. Exp Cell Res. 2011;317:20-8 pubmed publisher
	Li Y, Hu H, O Neil R. Caveolae facilitate TRPV4-mediated Ca2+ signaling and the hierarchical activation of Ca2+-activated K+ channels in K+-secreting renal collecting duct cells. Am J Physiol Renal Physiol. 2018;315:F1626-F1636 pubmed publisher
	Knopf J, Tholen S, Koczorowska M, De Wever O, Biniossek M, Schilling O. The stromal cell-surface protease fibroblast activation protein-Î± localizes to lipid rafts and is recruited to invadopodia. Biochim Biophys Acta. 2015;1853:2515-25 pubmed publisher
	Souto R, Vallega G, Wharton J, Vinten J, Tranum Jensen J, Pilch P. Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling. J Biol Chem. 2003;278:18321-9 pubmed

image

image 1 :

Immunofluorescent analysis of Caveolin 1 in H-4-II-E Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a Caveolin 1 monoclonal antibody (Product # MA3-600) at a dilution of 1:200 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product # 35503). Caveolin 1 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

product information

Product Type :

Antibody

Product Name :

Caveolin 1 Monoclonal Antibody (7C8)

Catalog # :

MA3-600

Quantity :

100 µL

Price :

US 375.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Hamster, Human, Rat

Applications :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:125, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 1-3 µL, Western Blot: 1:200-1:2,000

Species :

Hamster, Human, Rat

Clone :

7C8

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

Immunogen :

Intercellular membrane protein-containing vesicles (containing GLUT4) from rat.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:125, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: 1-3 µL, Western Blot: 1:200-1:2,000

Aliases :

BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04

more info or order :

Invitrogen product webpage