HIP Monoclonal Antibody (2G6) | Invitrogen MA3-413 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HIP Monoclonal Antibody (2G6)

catalog :

MA3-413

quantity :

50 µL

price :

US 420

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2G6

reactivity :

human, mouse, chicken, domestic rabbit

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 7

Reference
Kang D, Park J, Shim K. Heat Treatment at an Early Age Has Effects on the Resistance to Chronic Heat Stress on Broilers. Animals (Basel). 2019;9: pubmed publisher
Hostetter D, Loeb C, Chu F, Craik C. Hip is a pro-survival substrate of granzyme B. J Biol Chem. 2007;282:27865-74 pubmed
Kanelakis K, Murphy P, Galigniana M, Morishima Y, Takayama S, Reed J, et al. hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1. Biochemistry. 2000;39:14314-21 pubmed
Kanelakis K, Morishima Y, Dittmar K, Galigniana M, Takayama S, Reed J, et al. Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery. J Biol Chem. 1999;274:34134-40 pubmed
Prapapanich V, Chen S, Smith D. Mutation of Hip's carboxy-terminal region inhibits a transitional stage of progesterone receptor assembly. Mol Cell Biol. 1998;18:944-52 pubmed
Prapapanich V, Chen S, Nair S, Rimerman R, Smith D. Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein. Mol Endocrinol. 1996;10:420-31 pubmed
Hohfeld J, Minami Y, Hartl F. Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. Cell. 1995;83:589-98 pubmed

product information

Product Type :

Antibody

Product Name :

HIP Monoclonal Antibody (2G6)

Catalog # :

MA3-413

Quantity :

50 µL

Price :

US 420

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Chicken, Human, Mouse, Rabbit

Applications :

Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunoprecipitation: Assay-dependent, Western Blot: 1:250-1:1,000

Species :

Chicken, Human, Mouse, Rabbit

Clone :

2G6

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene.

Immunogen :

Recombinant human Hip protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:20, Immunocytochemistry: 1:250, Immunoprecipitation: Assay-dependent, Western Blot: 1:250-1:1,000

Aliases :

1110007I03Rik; 3110002K08Rik; AAG2; aging-associated protein 2; AW555194; FAM10A1; FAM10A4; heat shock 70kD protein binding protein; hedgehog interacting protein; hedgehog-interacting protein; HHIP; HIP; HOP; Hsc70-interacting protein; Hsp70 interacting protein; Hsp70-interacting protein; HSPABP; HSPABP1; hypothetical protein; p48; PRO0786; Progesterone receptor-associated p48 protein; Protein FAM10A1; Protein ST13 homolog; putative tumor suppressor ST13; RCJMB04_6h13; Renal carcinoma antigen NY-REN-33; SNC6; ST13; ST13 Hsp70 interacting protein; ST13, Hsp70 interacting protein; ST13P5; suppression of tumorigenicity 13; suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein); suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 5; suppression of tumorigenicity 13 (colon carcinoma) Hsp70-interacting protein; suppression of tumorigenicity 13 protein; testis secretory sperm-binding protein Li 233m; UNQ5825/PRO19644