ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 647 | Invitrogen MA3-39100-A647 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 647

catalog :

MA3-39100-A647

quantity :

50 uL

price :

US 432.00

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

ZO1-1A12

reactivity :

human, dogs

application :

immunocytochemistry

citations: 9

Reference
Shin M, Lee J, Lee H, Kumar V, Kim J, Park S. Deup1 Expression Interferes with Multiciliated Differentiation. Mol Cells. 2023;46:746-756 pubmed publisher
Li C, Liu Z, Anderson J, Liu Z, Tang L, Li Y, et al. Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells. PLoS ONE. 2023;18:e0295009 pubmed publisher
Kim J, Lee E, Seo J, Lee Y, Ahn Y, Park S, et al. Nephrin expression in human epidermal keratinocytes and its implication in poor wound closure. FASEB J. 2022;36:e22424 pubmed publisher
Shi X, Wang Z, Ren W, Chen L, Xu C, Li M, et al. LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB). Signal Transduct Target Ther. 2022;7:175 pubmed publisher
Liu Z, Anderson J, Natt J, Guimbellot J. Culture and Imaging of Human Nasal Epithelial Organoids. J Vis Exp. 2021;: pubmed publisher
Kutova O, Sencha L, Pospelov A, Dobrynina O, Brilkina A, Cherkasova E, et al. Comparative Analysis of Cell-Cell Contact Abundance in Ovarian Carcinoma Cells Cultured in Two- and Three-Dimensional In Vitro Models. Biology (Basel). 2020;9: pubmed publisher
Liu Z, Anderson J, Deng L, Mackay S, Bailey J, Kersh L, et al. Human Nasal Epithelial Organoids for Therapeutic Development in Cystic Fibrosis. Genes (Basel). 2020;11: pubmed publisher
Yu B, Ma J, Li J, Wang D, Wang Z, Wang S. Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics. Nat Commun. 2020;11:2549 pubmed publisher
Pena Philippides J, Gardiner A, Caballero Garrido E, Pan R, Zhu Y, Roitbak T. Inhibition of MicroRNA-155 Supports Endothelial Tight Junction Integrity Following Oxygen-Glucose Deprivation. J Am Heart Assoc. 2018;7: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 647

Catalog # :

MA3-39100-A647

Quantity :

50 uL

Price :

US 432.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Canine, Human

Applications :

Immunocytochemistry: 1-10 ug/mL

Species :

Canine, Human

Clone :

ZO1-1A12

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.

Immunogen :

Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-10 ug/mL

Aliases :

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1