ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 555 | Invitrogen MA3-39100-A555 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 555

catalog :

MA3-39100-A555

quantity :

50 uL

price :

US 425.00

clonality :

monoclonal

host :

mouse

conjugate :

Alexa Fluor 555

clone name :

ZO1-1A12

reactivity :

human, dogs

application :

immunocytochemistry

citations: 3

Reference
Koetemann A, Wollscheid B. Apicobasal Surfaceome Architecture Encodes for Polarized Epithelial Functionality and Depends on Tumor Suppressor PTEN. Int J Mol Sci. 2022;23: pubmed publisher
Bal xe1 zs A, Millar B xfc chner P, M xfc lleder M, Farztdinov V, Szyrwiel L, Addante A, et al. Age-Related Differences in Structure and Function of Nasal Epithelial Cultures From Healthy Children and Elderly People. Front Immunol. 2022;13:822437 pubmed publisher
Wiedenmann S, Breunig M, Merkle J, von Toerne C, Georgiev T, Moussus M, et al. Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip. Nat Biomed Eng. 2021;5:897-913 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 555

Catalog # :

MA3-39100-A555

Quantity :

50 uL

Price :

US 425.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Canine, Human

Applications :

Immunocytochemistry: 1-10 ug/mL

Species :

Canine, Human

Clone :

ZO1-1A12

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.

Immunogen :

Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-10 ug/mL

Aliases :

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1