ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 488 | Invitrogen MA3-39100-A488 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 488

catalog :

MA3-39100-A488

quantity :

50 uL

price :

US 432.00

clonality :

monoclonal

host :

mouse

conjugate :

AF488

clone name :

ZO1-1A12

reactivity :

human, dogs

application :

immunocytochemistry

citations: 3

Reference
Lee C, Kuo C, Liang C, Pan H, Shen C, Lee C. Effects of the media conditioned by various macrophage subtypes derived from THP-1 cells on tunneling nanotube formation in pancreatic cancer cells. BMC Mol Cell Biol. 2022;23:26 pubmed publisher
Sharma R, George A, Nimmagadda M, Ortolan D, Karla B, Qureshy Z, et al. Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model. Nat Commun. 2021;12:7293 pubmed publisher
Han X, Lu Y, Xie J, Zhang E, Zhu H, Du H, et al. Zwitterionic micelles efficiently deliver oral insulin without opening tight junctions. Nat Nanotechnol. 2020;15:605-614 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 488

Catalog # :

MA3-39100-A488

Quantity :

50 uL

Price :

US 432.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Canine, Human

Applications :

Immunocytochemistry: 1:100-1:1,000

Species :

Canine, Human

Clone :

ZO1-1A12

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.

Immunogen :

Human recombinant ZO-1 fusion protein encompassing amino acids 334-634

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000

Aliases :

DKFZp686M05161; I79_005485; MGC133289; OTTHUMP00000174520; Tight junction protein 1; tight junction protein 1 (zona occludens 1); tight junction protein ZO-1; Tjp1; zo1; ZO-1; ZO-1 MDCK; zona occludens 1; zona occludens protein 1; zonula occludens 1; zonula occludens 1 protein; zonula occludens protein 1