TSH Receptor Monoclonal Antibody (49) | Invitrogen MA3-218 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TSH Receptor Monoclonal Antibody (49)

catalog :

MA3-218

quantity :

100 uL

price :

US 440.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human, pigs

application :

western blot, ELISA, immunocytochemistry

citations: 3

Reference
Bagriacik E, Klein J. The thyrotropin (thyroid-stimulating hormone) receptor is expressed on murine dendritic cells and on a subset of CD45RBhigh lymph node T cells: functional role for thyroid-stimulating hormone during immune activation. J Immunol. 2000;164:6158-65 pubmed
Patibandla S, Seetharamaiah G, Dallas J, Thotakura N, Peake R, Prabhakar B. Differential reactivities of recombinant glycosylated ectodomains of mouse and human thyrotropin receptors with patient autoantibodies. Endocrinology. 1997;138:1559-66 pubmed
Seetharamaiah G, Wagle N, Morris J, Prabhakar B. Generation and characterization of monoclonal antibodies to the human thyrotropin (TSH) receptor: antibodies can bind to discrete conformational or linear epitopes and block TSH binding. Endocrinology. 1995;136:2817-24 pubmed

product information

Product Type :

Antibody

Product Name :

TSH Receptor Monoclonal Antibody (49)

Catalog # :

MA3-218

Quantity :

100 uL

Price :

US 440.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Porcine

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 1:250, Western Blot: 1:250

Species :

Human, Porcine

Clone :

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

TSH Receptor gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Purified extracellular domain of recombinant human thyrotropin receptor.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 1:250, Western Blot: 1:250

Aliases :

AI481368; CHNG1; hTSHR-I; hypothroid; hyt; LGR3; MGC141920; pet; seven transmembrane helix receptor; thyroid stimulating hormone receptor; thyroid stimulating hormone receptor, isoform 2; thyroid-stimulating hormone receptor; thyroid-stimulating hormone receptor variant; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSHR; TSH-R; TSHR; seven transmembrane domain G protein-coupled receptor; TSHRA