GCN5 Monoclonal Antibody (2GC-2C11) | Invitrogen MA3-046 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GCN5 Monoclonal Antibody (2GC-2C11)

catalog :

MA3-046

quantity :

50 uL

price :

US 491.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2GC-2C11

reactivity :

human

application :

western blot

citations: 1

Reference
Fournier M, Orpinell M, Grauffel C, Scheer E, Garnier J, Ye T, et al. KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification. Nat Commun. 2016;7:13227 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GCN5 Monoclonal Antibody (2GC-2C11)

Catalog # :

MA3-046

Quantity :

50 uL

Price :

US 491.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human

Applications :

ChIP Assay: 1:100, Western Blot: 1:2,000

Species :

Human

Clone :

2GC-2C11

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

SAGA (Spt-Ada-Gen5 histone acetyltransferase complex) is a histoneacetylase complex which has Gcn5p as catalyst subunit and functions overlapping with the fundamental transcription factor TFIID which has Taf1p as catalyst subunit. However, SAGA and TFIID have different allotment and each accomplishes the important role in the transcription for Housekeeping gene group and Stress Responding gene group. Also, SAGA is a gigantic protein complex which is composed of Ada protein group (5 kinds), TBP related protein group (4 kinds), TAF protein group (5 kinds that also pertain to TFIID), and other protein groups (>6 kinds). As its molecular function, there is the chemical modification of histone, or the recruitment by direct interaction of transcription regulating factor on DNA, or the control of transcription starting reaction by TBP. Gcn5p that show histoneacetylase activity is one kind of the above-mentioned Ada protein group, and in the case of budding yeast it is composed of 439 amino acid residues.

Immunogen :

Synthetic peptide coupled to ovalbumin corresponding to amino acids 118-132 of human GCN5: CKCNGWKNPKPPTAP.

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 1:100, Western Blot: 1:2,000

Aliases :

1110051E14Rik; AAS104; ADA4; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; Gcn5l2; general control of amino acid synthesis 5-like 2; general control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2; Kat2a; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97; SWI9; YGR252W