This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TCP1 Monoclonal Antibody (91A)
catalog :
MA3-026
quantity :
100 uL
price :
US 471.00
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
91a

The same clone is also sold as:
reactivity :
Saccharomyces cerevisiae S288C, Chinese hamsters, human, mouse, rat, dogs, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 5
Reference
Ratto E, Chowdhury S, Siefert N, Schneider M, Wittmann M, Helm D, et al. Direct control of lysosomal catabolic activity by mTORC1 through regulation of V-ATPase assembly. Nat Commun. 2022;13:4848 pubmed publisher
LeBlanc L, Kim M, Kambhampati A, Son A, Ramirez N, Kim J. β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation. iScience. 2022;25:103541 pubmed publisher
Banks C, Miah S, Adams M, Eubanks C, Thornton J, Florens L, et al. Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly. Sci Rep. 2018;8:13712 pubmed publisher
Kubota H, Hynes G, Carne A, Ashworth A, Willison K. Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol. 1994;4:89-99 pubmed
Willison K, Lewis V, Zuckerman K, Cordell J, Dean C, Miller K, et al. The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes. Cell. 1989;57:621-32 pubmed
product information
Product Type :
Antibody
Product Name :
TCP1 Monoclonal Antibody (91A)
Catalog # :
MA3-026
Quantity :
100 uL
Price :
US 471.00
Clonality :
Monoclonal
Host :
Rat
Reactivity :
Canine, Chicken, Hamster, Human, Mouse, Non-human primate, Rat, Yeast
Applications :
Flow Cytometry: 1/100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Species :
Canine, Chicken, Hamster, Human, Mouse, Non-human primate, Rat, Yeast
Clone :
91A
Isotype :
IgG2a
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The T Complex Polypeptide 1 (TCP-1) is approximately 60 kDa protein constitutively expressed in almost all eukaryotic cells, and is upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP70) including high abundance, induction by environmental stress, and ATPase activity. The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55. The TCP-1 sequence shows nearly 40% identity to TF55, but only minimal similarity to HSP60 and GroEL.
Immunogen :
Bacterially expressed fragment of mouse TCP-1, residues 306-556.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1/100, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:20, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
Aliases :
65 kDa antigen; AI528772; c-cpn; CCT; Cct1; Ccta; CCTalpha; CCT-alpha; chaperonin-containing T-complex alpha subunit TCP1; chaperonin-containing T-complex polypeptide alpha subunit; cytosolic chaperonin containing t-complex polypeptide 1; D6S230E; hypothetical protein; p63; tailless complex polypeptide 1; tailless complex polypeptide 1A; Tailless complex polypeptide 1B; t-complex 1; t-complex polypeptide 1; t-complex protein 1; T-complex protein 1 alpha subunit-like protein; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha A; T-complex protein 1 subunit alpha B; T-complex protein 1, alpha subunit; Tcp1; Tcp-1; TCP-1-A; TCP-1-alpha; TCP-1-B; Tp63; TRic; Unknown (protein for MGC:133746); YD8142.13; YD8142B.04; YDR212W
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA