This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HSP90 alpha Monoclonal Antibody (3B6)
catalog :
MA3-010
quantity :
100 uL
price :
US 491.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3B6

The same clone is also sold as:
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 10
Reference
Tosi G, Regoli M, Altera A, Galvagni F, Arcuri C, Bacci T, et al. Heat Shock Protein 90 Involvement in the Development of Idiopathic Epiretinal Membranes. Invest Ophthalmol Vis Sci. 2020;61:34 pubmed publisher
Yoshikawa N, Yamamoto K, Shimizu N, Yamada S, Morimoto C, Tanaka H. The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor. Mol Endocrinol. 2005;19:1110-24 pubmed
Calvert M, Digilio L, Herr J, Coonrod S. Oolemmal proteomics--identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane. Reprod Biol Endocrinol. 2003;1:27 pubmed
Yoshikawa N, Makino Y, Okamoto K, Morimoto C, Makino I, Tanaka H. Distinct interaction of cortivazol with the ligand binding domain confers glucocorticoid receptor specificity: cortivazol is a specific ligand for the glucocorticoid receptor. J Biol Chem. 2002;277:5529-40 pubmed
Miura T, Ouchida R, Yoshikawa N, Okamoto K, Makino Y, Nakamura T, et al. Functional modulation of the glucocorticoid receptor and suppression of NF-kappaB-dependent transcription by ursodeoxycholic acid. J Biol Chem. 2001;276:47371-8 pubmed
Watanabe A, Miyamoto T, Katoh N, Takahashi Y. Effect of stages of lactation on the concentration of a 90-kilodalton heat shock protein in bovine mammary tissue. J Dairy Sci. 1997;80:2372-9 pubmed
Meng X, Devin J, Sullivan W, Toft D, Baulieu E, Catelli M. Mutational analysis of Hsp90 alpha dimerization and subcellular localization: dimer disruption does not impede "in vivo' interaction with estrogen receptor. J Cell Sci. 1996;109 ( Pt 7):1677-87 pubmed
van den Berg J, Smets L, Van Rooij H. Agonist-free transformation of the glucocorticoid receptor in human B-lymphoma cells. J Steroid Biochem Mol Biol. 1996;57:239-49 pubmed
Nimmesgern E, Hartl F. ATP-dependent protein refolding activity in reticulocyte lysate. Evidence for the participation of different chaperone components. FEBS Lett. 1993;331:25-30 pubmed
van den Berg J, Smets L, Hutchison K, Van Rooij H, van den Elshout M. High levels of non-activated receptors in glucocorticoid-sensitive S49wt mouse lymphoma cells incubated with dexamethasone. J Steroid Biochem Mol Biol. 1994;51:33-40 pubmed
product information
Product Type :
Antibody
Product Name :
HSP90 alpha Monoclonal Antibody (3B6)
Catalog # :
MA3-010
Quantity :
100 uL
Price :
US 491.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Bovine, Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1:500
Species :
Bovine, Human, Mouse, Rat
Clone :
3B6
Isotype :
IgG2b
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
Heat shock proteins (HSP) are proteins that are expressed in response to various biological stress, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, and some kinases. It has been suggested that HSP90 is necessary to maintain structural integrity of at least some steroid receptors to allow for ligand binding during receptor activation.
Immunogen :
Purified mouse HSP90.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1:500
Aliases :
86kDa; 89kDa; 90-kDa heat shock protein; 90-kDa heat shock protein alpha; akineto; AL024080; AL024147; EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; fb17b01; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 86; heat shock protein 90; heat shock protein 90 alpha family class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1; heat shock protein 90-alpha 1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein alpha; Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-alpha 1; heat shock protein HSP90 alpha; heat shock protein hsp90alpha; heat shock protein, 1; heat shock protein, 86 kDa 1; heat shock protein, 89 kDa; Heat shock protein90; HEL-S-65p; HSP; HSP 86; HSP 90 alpha; hsp4; HSP86; Hsp86-1; Hsp89; HSP89A; HSP90; hsp90a; hsp90a protein; hsp90a.1; hsp90aa1; hsp90aa1.1; hsp90alpha; HSP90N; HSPC1; Hspca; HSPCA protein; HSPCAL1; HSPCAL4; HSPN; hypothetical protein; LAP2; LAP-2; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; renal carcinoma antigen NY-REN-38; slo; sloth; TSTA; Tumor-specific transplantation 86 kDa antigen; wu:fb17b01; zgc:86652
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA