BAP31 Monoclonal Antibody (CC-4) | Invitrogen MA3-003 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BAP31 Monoclonal Antibody (CC-4)

catalog :

MA3-003

quantity :

100 uL

price :

US 520.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

CC-4

The same clone is also sold as:

Santa Cruz Biotechnology: sc-56008

reactivity :

Chinese hamsters, human, bovine

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

citations: 1

Reference
Zen K, Utech M, Liu Y, Soto I, Nusrat A, Parkos C. Association of BAP31 with CD11b/CD18. Potential role in intracellular trafficking of CD11b/CD18 in neutrophils. J Biol Chem. 2004;279:44924-30 pubmed

product information

Product Type :

Antibody

Product Name :

BAP31 Monoclonal Antibody (CC-4)

Catalog # :

MA3-003

Quantity :

100 uL

Price :

US 520.00

Clonality :

Monoclonal

Host :

Rat

Reactivity :

Bovine, Hamster, Human, Non-human primate

Applications :

Flow Cytometry: 1/100, Immunohistochemistry: 1:200-1:6,400, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,500

Species :

Bovine, Hamster, Human, Non-human primate

Clone :

CC-4

Isotype :

IgG2a

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo- and hetero-oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL-2/BCL-XL-associated protein. In the C-terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.

Immunogen :

Amino acid residues 123-229 of human BAP31.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1/100, Immunohistochemistry: 1:200-1:6,400, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,500

Aliases :

6C6 antigen; 6C6-AG; 6C6-AG tumor-associated antigen; accessory protein BAP31; B cell receptor associated protein 31; BAP31; Bcap31; B-cell receptor-associated protein 31; BCR-associated protein 31; BCR-associated protein Bap31; CDM; CDM protein; DDCH; DXS1357E; hypothetical protein LOC533949; OTTHUMP00000025978; p28; p28 Bap31; Protein CDM