BAP31 Monoclonal Antibody (CC-1) | Invitrogen MA3-002 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BAP31 Monoclonal Antibody (CC-1)

catalog :

MA3-002

quantity :

100 µL

price :

US 425.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

CC-1

reactivity :

African green monkey, Chinese hamsters, human, mouse, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...	Miller Vedam L, Bräuning B, Popova K, Schirle Oakdale N, Bonnar J, Prabu J, et al. Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. elife. 2020;9: pubmed publisher
immunocytochemistry; African green monkey; 1:500; fig 3	Ravindran M, Bagchi P, Inoue T, Tsai B. A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane. PLoS Pathog. 2015;11:e1005086 pubmed publisher
western blot; human	Bitler B, Goverdhan A, Schroeder J. MUC1 regulates nuclear localization and function of the epidermal growth factor receptor. J Cell Sci. 2010;123:1716-23 pubmed publisher
	Spriggs C, Badieyan S, Verhey K, Cianfrocco M, Tsai B. Golgi-associated BICD adaptors couple ER membrane penetration and disassembly of a viral cargo. J Cell Biol. 2020;219: pubmed publisher
	Ravindran M, Spriggs C, Verhey K, Tsai B. Dynein Engages and Disassembles Cytosol-Localized Simian Virus 40 To Promote Infection. J Virol. 2018;92: pubmed publisher
	Szczesna Skorupa E, Kemper B. BAP31 is involved in the retention of cytochrome P450 2C2 in the endoplasmic reticulum. J Biol Chem. 2006;281:4142-8 pubmed
	Zen K, Utech M, Liu Y, Soto I, Nusrat A, Parkos C. Association of BAP31 with CD11b/CD18. Potential role in intracellular trafficking of CD11b/CD18 in neutrophils. J Biol Chem. 2004;279:44924-30 pubmed

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product information

Product Type :

Antibody

Product Name :

BAP31 Monoclonal Antibody (CC-1)

Catalog # :

MA3-002

Quantity :

100 µL

Price :

US 425.00

Clonality :

Monoclonal

Host :

Rat

Reactivity :

Bovine, Hamster, Human, Mouse, Non-human primate

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Frozen): 1:1,000-1:10,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,500-1:6,000

Species :

Bovine, Hamster, Human, Mouse, Non-human primate

Clone :

CC-1

Isotype :

IgG2a

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo- and hetero-oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL-2/BCL-XL-associated protein. In the C-terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.

Immunogen :

Amino acid residues 230-246 of BAP31 protein.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Frozen): 1:1,000-1:10,000, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,500-1:6,000

Aliases :

6C6 antigen; 6C6-AG; 6C6-AG tumor-associated antigen; accessory protein BAP31; B cell receptor associated protein 31; BAP31; Bcap31; B-cell receptor-associated protein 31; BCR-associated protein 31; BCR-associated protein Bap31; CDM; CDM protein; DDCH; DXS1357E; hypothetical protein LOC533949; OTTHUMP00000025978; p28; p28 Bap31; Protein CDM

more info or order :

Invitrogen product webpage