product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CDK7 Monoclonal Antibody (31TF2-1F8)
catalog :
MA3-001
quantity :
50 µL
price :
US 425.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
31TF2-1F8
reactivity :
Artemia franciscana, Pacific oyster, rockcod, bay mussel, brown tegula, California mussel, green sea urchin , Sacramento splittail, Acartia tonsa, Corbula amurensis, bald rockcod, king salmon, Austrofundulus limnaeus, Maori chief, Notocypraea angustata, Balanus glandula, African green monkey, long-jawed mudsucker, Macoma nasuta, human, mouse, bovine, pigs , brewer's yeast
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
Invitrogen product webpage
citations: 38
Published Application/Species/Sample/DilutionReference
  • western blot; Artemia franciscana; 1:1250; loading ...; fig 10
Clegg J. Desiccation tolerance in encysted embryos of the animal extremophile, artemia. Integr Comp Biol. 2005;45:715-24 pubmed publisher
  • western blot; Acartia tonsa; 1:2500; fig 7a
Tartarotti B, Torres J. Sublethal stress: Impact of solar UV radiation on protein synthesis in the copepod Acartia tonsa. J Exp Mar Bio Ecol. 2009;375:106-113 pubmed
  • western blot; brewer's yeast; 1:2000; fig 3a
Zhang H, Hu B, Ji Y, Kato A, Song Y. The effect of calnexin deletion on the expression level of binding protein (BiP) under heat stress conditions in Saccharomyces cerevisiae. Cell Mol Biol Lett. 2008;13:621-31 pubmed publisher
  • western blot; king salmon; 1:500; loading ...; fig 1a
Eder K, Leutenegger C, Köhler H, Werner I. Effects of neurotoxic insecticides on heat-shock proteins and cytokine transcription in Chinook salmon (Oncorhynchus tshawytscha). Ecotoxicol Environ Saf. 2009;72:182-190 pubmed publisher
  • western blot; California mussel; loading ...; fig 2
Petes L, Mouchka M, Milston Clements R, Momoda T, Menge B. Effects of environmental stress on intertidal mussels and their sea star predators. Oecologia. 2008;156:671-80 pubmed publisher
  • western blot; Austrofundulus limnaeus; 1:1000; loading ...; fig 2a
Podrabsky J, Somero G. An inducible 70 kDa-class heat shock protein is constitutively expressed during early development and diapause in the annual killifish Austrofundulus limnaeus. Cell Stress Chaperones. 2007;12:199-204 pubmed
  • western blot; king salmon; 1:500; loading ...; fig 2
Eder K, Köhler H, Werner I. Pesticide and pathogen: heat shock protein expression and acetylcholinesterase inhibition in juvenile Chinook salmon in response to multiple stressors. Environ Toxicol Chem. 2007;26:1233-42 pubmed
  • western blot; Balanus glandula; 1:2500; fig 1
Berger M, Emlet R. Heat-shock response of the upper intertidal barnacle Balanus glandula: thermal stress and acclimation. Biol Bull. 2007;212:232-41 pubmed
  • western blot; Artemia franciscana; 1:1250; loading ...; fig 4
Clegg J, Campagna V. Comparisons of stress proteins and soluble carbohydrate in encysted embryos of Artemia franciscana and two species of Parartemia. Comp Biochem Physiol B Biochem Mol Biol. 2006;145:119-25 pubmed
  • western blot; long-jawed mudsucker; 1:2500; loading ...
Lund S, Ruberté M, Hofmann G. Turning up the heat: the effects of thermal acclimation on the kinetics of hsp70 gene expression in the eurythermal goby, Gillichthys mirabilis. Comp Biochem Physiol A Mol Integr Physiol. 2006;143:435-46 pubmed
  • western blot; bay mussel; 1:500; loading ...; fig 2
La Porte P. Mytilus trossulus hsp70 as a biomarker for arsenic exposure in the marine environment: laboratory and real-world results. Biomarkers. 2005;10:417-28 pubmed
  • western blot; rockcod; fig 1b
  • western blot; Maori chief; loading ...; fig 1b
Place S, Hofmann G. Temperature differentially affects adenosine triphosphatase activity in Hsc70 orthologs from Antarctic and New Zealand notothenioid fishes. Cell Stress Chaperones. 2005;10:104-13 pubmed
  • western blot; pigs ; 1:1000; loading ...; fig 1
Ryan P, Bedard K, Breining T, Cribb A. Disruption of the endoplasmic reticulum by cytotoxins in LLC-PK1 cells. Toxicol Lett. 2005;159:154-63 pubmed
  • western blot; bovine; fig 1d
  • western blot; Notocypraea angustata; fig 1d
  • western blot; rockcod; loading ...; fig 1d
  • western blot; bald rockcod; fig 1d
Place S, Hofmann G. Comparison of Hsc70 orthologs from polar and temperate notothenioid fishes: differences in prevention of aggregation and refolding of denatured proteins. Am J Physiol Regul Integr Comp Physiol. 2005;288:R1195-202 pubmed
  • western blot; Sacramento splittail; 1:500; fig 4a
Teh S, Deng D, Werner I, Teh F, Hung S. Sublethal toxicity of orchard stormwater runoff in Sacramento splittail (Pogonichthys macrolepidotus) larvae. Mar Environ Res. 2005;59:203-16 pubmed
  • western blot; long-jawed mudsucker; 1:2500; loading ...
Buckley B, Hofmann G. Magnitude and duration of thermal stress determine kinetics of hsp gene regulation in the goby Gillichthys mirabilis. Physiol Biochem Zool. 2004;77:570-81 pubmed
  • western blot; king salmon; 1:500; loading ...; fig 1
Eder K, Leutenegger C, Wilson B, Werner I. Molecular and cellular biomarker responses to pesticide exposure in juvenile chinook salmon (Oncorhynchus tshawytscha). Mar Environ Res. 2004;58:809-13 pubmed
  • western blot; Corbula amurensis; 1:500; fig 1
Werner I. The influence of salinity on the heat-shock protein response of Potamocorbula amurensis (Bivalvia). Mar Environ Res. 2004;58:803-7 pubmed
  • western blot; Macoma nasuta; 1:500; loading ...; tbl 1
Werner I, Teh S, Datta S, Lu X, Young T. Biomarker responses in Macoma nasuta (Bivalvia) exposed to sediments from northern San Francisco Bay. Mar Environ Res. 2004;58:299-304 pubmed
  • western blot; brown tegula; loading ...; fig 1b
Tomanek L, Sanford E. Heat-shock protein 70 (Hsp70) as a biochemical stress indicator: an experimental field test in two congeneric intertidal gastropods (genus: Tegula). Biol Bull. 2003;205:276-84 pubmed
  • western blot; Pacific oyster; loading ...; fig 4
Hamdoun A, Cheney D, Cherr G. Phenotypic plasticity of HSP70 and HSP70 gene expression in the Pacific oyster (Crassostrea gigas): implications for thermal limits and induction of thermal tolerance. Biol Bull. 2003;205:160-9 pubmed
  • immunocytochemistry; African green monkey; loading ...; fig 2a
Guerrero C, Bouyssounade D, Zárate S, Isa P, López T, Espinosa R, et al. Heat shock cognate protein 70 is involved in rotavirus cell entry. J Virol. 2002;76:4096-102 pubmed
  • western blot; Artemia franciscana; 1:1250; fig 3
Willsie J, Clegg J. Small heat shock protein p26 associates with nuclear lamins and HSP70 in nuclei and nuclear matrix fractions from stressed cells. J Cell Biochem. 2002;84:601-14 pubmed
  • western blot; California mussel; loading ...; fig 7
Helmuth B, Hofmann G. Microhabitats, thermal heterogeneity, and patterns of physiological stress in the rocky intertidal zone. Biol Bull. 2001;201:374-84 pubmed
  • western blot; bay mussel; loading ...; fig 4
Buckley B, Owen M, Hofmann G. Adjusting the thermostat: the threshold induction temperature for the heat-shock response in intertidal mussels (genus Mytilus) changes as a function of thermal history. J Exp Biol. 2001;204:3571-9 pubmed
  • western blot; long-jawed mudsucker; loading ...; fig 2b
Place S, Hofmann G. Temperature interactions of the molecular chaperone Hsc70 from the eurythermal marine goby Gillichthys mirabilis. J Exp Biol. 2001;204:2675-82 pubmed
  • western blot; Corbula amurensis; 1:500; loading ...; fig 2
Werner I, Hinton D. Spatial profiles of hsp70 proteins in Asian clam (Potamocorbula amurensis) in northern San Francisco Bay may be linked to natural rather than anthropogenic stressors. Mar Environ Res. 2000;50:379-84 pubmed
  • immunohistochemistry; Corbula amurensis; loading ...; fig 2
Teh S, Werner I, Hinton D. Sublethal effects of chromium-VI in the Asian clam (Potamocorbula amurensis). Mar Environ Res. 2000;50:295-300 pubmed
  • western blot; green sea urchin ; fig 6
Stephens R. Ciliary protein turnover continues in the presence of inhibitors of golgi function: evidence for membrane protein pools and unconventional intracellular membrane dynamics. J Exp Zool. 2001;289:335-49 pubmed
  • western blot; Artemia franciscana; loading ...; fig 10
Clegg J, Jackson S, Popov V. Long-term anoxia in encysted embryos of the crustacean, Artemia franciscana: viability, ultrastructure, and stress proteins. Cell Tissue Res. 2000;301:433-46 pubmed
  • western blot; rockcod; loading ...; fig 4
Hofmann G, Buckley B, Airaksinen S, Keen J, Somero G. Heat-shock protein expression is absent in the antarctic fish Trematomus bernacchii (family Nototheniidae). J Exp Biol. 2000;203:2331-9 pubmed
  • western blot; rockcod; loading ...; fig 2
Carpenter C, Hofmann G. Expression of 70 kDa heat shock proteins in antarctic and New Zealand notothenioid fish. Comp Biochem Physiol A Mol Integr Physiol. 2000;125:229-38 pubmed
Olabarria C, Gestoso I, Lima F, Vázquez E, Comeau L, Gomes F, et al. Response of Two Mytilids to a Heatwave: The Complex Interplay of Physiology, Behaviour and Ecological Interactions. PLoS ONE. 2016;11:e0164330 pubmed publisher
Baladi S, Kantengwa S, Donati Y, Polla B. Effects of the Bacterial Extract OM-85 on Phagocyte Functions and the Stress Response. Mediators Inflamm. 1994;3:143-8 pubmed
Tanguay J, Reyes R, Clegg J. Habitat diversity and adaptation to environmental stress in encysted embryos of the crustacean Artemia. J Biosci. 2004;29:489-501 pubmed
Werner I, Geist J, Okihiro M, Rosenkranz P, Hinton D. Effects of dietary exposure to the pyrethroid pesticide esfenvalerate on medaka (Oryzias latipes). Mar Environ Res. 2002;54:609-14 pubmed
Buckley B, Hofmann G. Thermal acclimation changes DNA-binding activity of heat shock factor 1 (HSF1) in the goby Gillichthys mirabilis: implications for plasticity in the heat-shock response in natural populations. J Exp Biol. 2002;205:3231-40 pubmed
Tomanek L, Somero G. Interspecific- and acclimation-induced variation in levels of heat-shock proteins 70 (hsp70) and 90 (hsp90) and heat-shock transcription factor-1 (HSF1) in congeneric marine snails (genus Tegula): implications for regulation of hsp gene expression. J Exp Biol. 2002;205:677-85 pubmed
product information
Product Type :
Antibody
Product Name :
CDK7 Monoclonal Antibody (31TF2-1F8)
Catalog # :
MA3-001
Quantity :
50 µL
Price :
US 425.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Western Blot: 1:1,000-1:2,000
Species :
Human, Mouse
Clone :
31TF2-1F8
Isotype :
IgG1, kappa
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.
Immunogen :
Synthetic peptide MALDVKSRAKRYEKLDFLGEGQ corresponding to aa 1-22 of human CDK7
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:1,000-1:2,000
Aliases :
39 KDa protein kinase; 39 protein kinase; AI323415; AI528512; C230069N13; CAK; CAK1; CDK; CDK7; CDK-activating kinase; CDK-activating kinase 1; Cdkn7; cell division protein kinase 7; CR4 protein kinase; CRK4; CRK4 PK (CDC2-related-kinase-4 protein kinase); cyclin dependent kinase 7; cyclin-dependent kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); EC 2.7.11.22; EC 2.7.11.23; HCAK; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; MO15; Mpk-7; OTTHUMP00000222032; OTTHUMP00000222033; p39 Mo15; p39MO15; Protein-tyrosine kinase MPK-7; serine/threonine kinase stk1; serine/threonine protein kinase 1; serine/threonine protein kinase MO15; Serine/threonine-protein kinase 1; STK1; TFIIH basal transcription factor complex kinase subunit
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA