DIABLO Monoclonal Antibody (SMAC 17 1-87) | Invitrogen MA1-936 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DIABLO Monoclonal Antibody (SMAC 17 1-87)

catalog :

MA1-936

quantity :

100 ug

price :

US 471.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SMAC 17 1-87

The same clone is also sold as:

Abcam: ab111893

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 1

Reference
Pablos A, Ceca D, Jorda A, Rivera P, Colmena C, Elvira L, et al. Protective Effects of Foam Rolling against Inflammation and Notexin Induced Muscle Damage in Rats. Int J Med Sci. 2020;17:71-81 pubmed publisher

product information

Product Type :

Antibody

Product Name :

DIABLO Monoclonal Antibody (SMAC 17 1-87)

Catalog # :

MA1-936

Quantity :

100 ug

Price :

US 471.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL

Species :

Human, Mouse, Rat

Clone :

SMAC 17 1-87

Isotype :

IgG1

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

DIABLO (smac), a mitochondrial protein, activates various forms of apoptosis. This activation may be due to the neutralization of one or more members of the IAP family of apoptosis inhibitory proteins. Smac exits the mitochondria and enter the cytosol during certain apoptosis triggered events. Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders. Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol. The release of these proteins, however, occurs via different mechanisms. Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced).

Immunogen :

C-Terminal His tagged recombinant human Smac/DIABLO.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Immunoprecipitation: Assay-dependent, Western Blot: 1 ug/mL

Aliases :

0610041G12Rik; 1700006L01Rik; AU040403; DFNA64; DIABLO; diablo homolog (Drosophila); diablo homolog, mitochondrial; diablo IAP-binding mitochondrial protein; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; direct IAP binding protein with low PI; direct IAP-binding protein with low pI; FLJ10537; FLJ25049; hCG_1782202; Second mitochondria-derived activator of caspase; Smac; Smac protein; SMAC3