Histone H1 Monoclonal Antibody (0.T.60) | Invitrogen MA1-91853 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Histone H1 Monoclonal Antibody (0.T.60)

catalog :

MA1-91853

quantity :

50µg

price :

US 345

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

0.T.60

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

Histone H1 Monoclonal Antibody (0.T.60)

Catalog # :

MA1-91853

Quantity :

50µg

Price :

US 345

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

ELISA: Assay Dependent, Immunocytochemistry: 5-20 µg/mL, Immunofluorescence: 5-20 µg/mL, Western Blot: 0.5-2 µg/mL

Species :

Human

Clone :

0.T.60

Isotype :

IgG2a

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Although histones are classified into a limited number of types of fractions with each particular fraction having a fundamentally distinct amino acid composition and sequence, numerous subfractions are observed due to the acetylation, methylation, and phosphorylation of various amino acid residues. Microheterogeneity or alteration of structure is dynamic such that the histones of a single cell type are found to vary during development. They are believed to play a role in gene activity and cellular metabolism. Histones are believed to be regularly arranged in the deep groove of the DNA helix. The recurring positive charges of the histones form electrostatic associations with the negatively charged phosphate groups of DNA making the DNA more stable and flexible. This allows for the supercoiling of the chromatin fibers. With the exception of H1, the primary structures of the calf thymus histones have been determined. Comparisons with the structures for histones from other sources indicate that the histones rank among the most highly conserved (low mutation rate) proteins in nature.

Immunogen :

Nuclei from myeloid leukemia biopsy cells.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Immunocytochemistry: 5-20 µg/mL, Immunofluorescence: 5-20 µg/mL, Western Blot: 0.5-2 µg/mL