PGRP-1b Monoclonal Antibody (186C426) | Invitrogen MA1-91734 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PGRP-1b Monoclonal Antibody (186C426)

catalog :

MA1-91734

quantity :

100 µg

price :

US 413.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

186C426

reactivity :

human

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

PGRP-1b Monoclonal Antibody (186C426)

Catalog # :

MA1-91734

Quantity :

100 µg

Price :

US 413.00

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Human

Applications :

Immunocytochemistry: 1:10-1:2,000, Western Blot: 2 µg/mL

Species :

Human

Clone :

186C426

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1, 2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-I beta) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4-5).

Immunogen :

synthetic peptide CSQRLRELQAHHVHNN conjugated to KLH, corresponding to amino acids 95-110 of Human PGRP1B.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:2,000, Western Blot: 2 µg/mL

Aliases :

Gm1478; Gm413; Peptidoglycan recognition protein 4; peptidoglycan recognition protein I beta; peptidoglycan recognition protein I-beta; Peptidoglycan recognition protein intermediate beta; peptidoglycan recognition protein-I-beta; PGLYRP4; PGLYRPIbeta; PGRPIB; PGRP-Ibeta; PGRP-I-beta; SBBI67