Nestin Monoclonal Antibody (2Q178) | Invitrogen MA1-91657 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nestin Monoclonal Antibody (2Q178)

catalog :

MA1-91657

quantity :

50 µg

price :

US 425.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2Q178

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500	Ricci G, Guglielmo M, Caruso M, Ferranti F, Canipari R, Galdieri M, et al. Hepatocyte growth factor is a mouse fetal Leydig cell terminal differentiation factor. Biol Reprod. 2012;87:146 pubmed publisher
	Poston R, Dunn C, Sarkar P, Saha R. Persistent 6-OH-BDE-47 exposure impairs functional neuronal maturation and alters expression of neurodevelopmentally-relevant chromatin remodelers. Environ Epigenet. 2018;4:dvx020 pubmed publisher
	Adorno M, Sikandar S, Mitra S, Kuo A, Nicolis Di Robilant B, Haro Acosta V, et al. Usp16 contributes to somatic stem-cell defects in Down's syndrome. Nature. 2013;501:380-4 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nestin Monoclonal Antibody (2Q178)

Catalog # :

MA1-91657

Quantity :

50 µg

Price :

US 425.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Mouse, Rat

Applications :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Frozen): 1:20-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Species :

Mouse, Rat

Clone :

2Q178

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

Immunogen :

Full length native Nestin protein purified from embryonic rat spinal cord.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Frozen): 1:20-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Immunohistochemistry: Assay-dependent, Western Blot: Assay-dependent

Aliases :

AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin

more info or order :

Invitrogen product webpage