HSF2 Monoclonal Antibody (3E2) | Invitrogen MA1-91597 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HSF2 Monoclonal Antibody (3E2)

catalog :

MA1-91597

quantity :

500 µL

price :

US 399.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

3E2

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Lee Y, Lee H, Lee J, Jeoung D, Kang C, Bae S, et al. A novel function for HSF1-induced mitotic exit failure and genomic instability through direct interaction between HSF1 and Cdc20. Oncogene. 2008;27:2999-3009 pubmed
	Mathew A, Mathur S, Jolly C, Fox S, Kim S, Morimoto R. Stress-specific activation and repression of heat shock factors 1 and 2. Mol Cell Biol. 2001;21:7163-71 pubmed
	Scheynius A, Camp R, Pure E. Reduced contact sensitivity reactions in mice treated with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1. J Immunol. 1993;150:655-63 pubmed

product information

Product Type :

Antibody

Product Name :

HSF2 Monoclonal Antibody (3E2)

Catalog # :

MA1-91597

Quantity :

500 µL

Price :

US 399.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Rat

Reactivity :

Human, Mouse, Non-human primate

Applications :

Immunocytochemistry: Assay-dependent, Immunoprecipitation: 1:400, Western Blot: 1:200

Species :

Human, Mouse, Non-human primate

Clone :

3E2

Isotype :

IgG1

Storage :

4° C, do not freeze

Description :

Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing a group of genes collectively designated heat shock genes. In eukaryotes, this gene expression is regulated primarily at the transcription level. Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.

Immunogen :

Recombinant mouse HSF2 protein (aa1-517)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-dependent, Immunoprecipitation: 1:400, Western Blot: 1:200

Aliases :

AI661205; heat shock factor 2; heat shock factor protein 2; Heat shock transcription factor 2; HSF 2; Hsf2; HSTF 2; HSTF2; MGC117376; MGC156196; MGC75048

more info or order :

Invitrogen product webpage