N-cadherin Monoclonal Antibody (CH-19) | Invitrogen MA1-91128 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

N-cadherin Monoclonal Antibody (CH-19)

catalog :

MA1-91128

quantity :

100 uL

price :

US 538.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CH-19

reactivity :

guinea pig, domestic goat, Chinese hamsters, human, mouse, rat, dogs, chicken, bovine, pigs , cat, domestic sheep, domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; loading ...; fig 3a immunohistochemistry - paraffin section; human; loading ...; fig 1a, 2g	Sun Y, Jing J, Xu H, Xu L, Hu H, Tang C, et al. N-cadherin inhibitor creates a microenvironment that protect TILs from immune checkpoints and Treg cells. J Immunother Cancer. 2021;9: pubmed publisher
western blot; mouse; loading ...; fig 1a	Szewczyk L, Brozko N, Nagalski A, RÃ¶ckle I, Werneburg S, Hildebrandt H, et al. ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons. Glia. 2017;65:34-49 pubmed publisher
	Li J, Jiang J, Chen Y, Lu W. KLF2 inhibits colorectal cancer progression and metastasis by inducing ferroptosis via the PI3K/AKT signaling pathway. J Pathol Clin Res. 2023;9:423-435 pubmed publisher
	Moskalik A, Ratajska A, Majchrzak B, Jankowska Steifer E, Bartkowiak K, Bartkowiak M, et al. miR-31-5p-Modified RAW 264.7 Macrophages Affect Profibrotic Phenotype of Lymphatic Endothelial Cells In Vitro. Int J Mol Sci. 2022;23: pubmed publisher
	Liu X, Chen B, Chen J, Su Z, Sun S. Deubiquitinase ubiquitin-specific peptidase 10 maintains cysteine rich angiogenic inducer 61 expression via Yes1 associated transcriptional regulator to augment immune escape and metastasis of pancreatic adenocarcinoma. Cancer Sci. 2022;113:1868-1879 pubmed publisher
	Takko H, Pajanoja C, Kurtzeborn K, Hsin J, Kuure S, Kerosuo L. ShapeMetrics: A userfriendly pipeline for 3D cell segmentation and spatial tissue analysis. Dev Biol. 2020;462:7-19 pubmed publisher
	J xf8 rgensen E, Pirone A, Jacobsen S, Miragliotta V. Epithelial-to-mesenchymal transition and keratinocyte differentiation in equine experimental body and limb wounds healing by second intention. Vet Dermatol. 2019;30:417-e126 pubmed publisher

product information

Product Type :

Antibody

Product Name :

N-cadherin Monoclonal Antibody (CH-19)

Catalog # :

MA1-91128

Quantity :

100 uL

Price :

US 538.00

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Bovine, Canine, Chicken, Feline, Goat, Guinea Pig, Hamster, Human, Mouse, Ovine, Porcine, Rabbit, Rat, Reptile

Applications :

Immunocytochemistry: 1:500, Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:500

Species :

Bovine, Canine, Chicken, Feline, Goat, Guinea Pig, Hamster, Human, Mouse, Ovine, Porcine, Rabbit, Rat, Reptile

Clone :

CH-19

Isotype :

IgG1

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.

Immunogen :

synthetic peptide DYDYLNDWGPRFKKLADMYGGGDD conjugated to KLH, corresponding to amino acids 889-912 of Chicken N-Cadherin (cdh2).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:500, Immunohistochemistry (Paraffin): 1:500, Western Blot: 1:500

Aliases :

bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1 preproprotein; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; CDH2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; neural cadherin; Neural cadherin A; neural cadherin-2; neural calcium-dependent cell adhesion molecule; neural-cadherin; pac; Parachute; unnamed protein product; wu:fb47h04; XELAEV_18031953mg; ZNCAD

more info or order :

Invitrogen product webpage