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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 5/6 Monoclonal Antibody (D5/16 B4)
catalog :
MA1-91106
quantity :
250 uL
price :
US 532.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D5/16 B4
reactivity :
human, dogs, cat
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 30
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; dogs; fig 2g
Levi M, Muscatello L, Brunetti B, Benazzi C, Parenti F, Gobbo F, et al. High Intrinsic Expression of P-glycoprotein and Breast Cancer Resistance Protein in Canine Mammary Carcinomas Regardless of Immunophenotype and Outcome. Animals (Basel). 2021;11: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:75; tbl 2
Hsieh M, Wang H, Lee Y, Ko J, Chang Y. Reevaluation of MAML2 fusion-negative mucoepidermoid carcinoma: a subgroup being actually hyalinizing clear cell carcinoma of the salivary gland with EWSR1 translocation. Hum Pathol. 2017;61:9-18 pubmed publisher
  • immunohistochemistry - paraffin section; cat; 1:100
  • immunohistochemistry - paraffin section; dogs; 1:100
Muscatello L, Sarli G, Beha G, Asproni P, Millanta F, Poli A, et al. Validation of tissue microarray for molecular profiling of canine and feline mammary tumours. J Comp Pathol. 2015;152:153-60 pubmed publisher
  • immunohistochemistry - paraffin section; human
Moser B, Schiefer A, Janik S, Marx A, Prosch H, Pohl W, et al. Adenocarcinoma of the thymus, enteric type: report of 2 cases, and proposal for a novel subtype of thymic carcinoma. Am J Surg Pathol. 2015;39:541-8 pubmed publisher
  • immunohistochemistry - paraffin section; human
Abdelzaher E, Abdallah D. Expression of mesothelioma-related markers in meningiomas: an immunohistochemical study. Biomed Res Int. 2014;2014:968794 pubmed publisher
  • immunohistochemistry; human
Lien H, Lee Y, Jeng Y, Lin C, Lu Y, Yao Y. Differential expression of hyaluronan synthase 2 in breast carcinoma and its biological significance. Histopathology. 2014;65:328-39 pubmed publisher
  • immunohistochemistry; human; 1:100
Andres R, Pajares I, Balmana J, Llort G, Ramon Y Cajal T, Chirivella I, et al. Association of BRCA1 germline mutations in young onset triple-negative breast cancer (TNBC). Clin Transl Oncol. 2014;16:280-4 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 2
Zhang J, Wang Y, Yin Q, Zhang W, Zhang T, Niu Y. An associated classification of triple negative breast cancer: the risk of relapse and the response to chemotherapy. Int J Clin Exp Pathol. 2013;6:1380-91 pubmed
  • immunohistochemistry; human; tbl 3
Blanchard A, Ma X, Dueck K, Penner C, Cooper S, Mulhall D, et al. Claudin 1 expression in basal-like breast cancer is related to patient age. BMC Cancer. 2013;13:268 pubmed publisher
  • immunohistochemistry; human; fig 2
Yang G, Li J, Jin H, Ding H. Is mammary not otherwise specified-type sarcoma with CD10 expression a distinct entity? A rare case report with immunohistochemical and ultrastructural study. Diagn Pathol. 2013;8:14 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 1:100
Beha G, Brunetti B, Asproni P, Muscatello L, Millanta F, Poli A, et al. Molecular portrait-based correlation between primary canine mammary tumor and its lymph node metastasis: possible prognostic-predictive models and/or stronghold for specific treatments?. BMC Vet Res. 2012;8:219 pubmed publisher
  • immunohistochemistry - paraffin section; dogs; 1:100; tbl 2
Beha G, Sarli G, Brunetti B, Sassi F, Ferrara D, Benazzi C. Morphology of the myoepithelial cell: immunohistochemical characterization from resting to motile phase. ScientificWorldJournal. 2012;2012:252034 pubmed publisher
  • immunohistochemistry; human
Zhou Z, Yang G, Zhou J, Yu M. Significance of TRIM29 and β-catenin expression in non-small-cell lung cancer. J Chin Med Assoc. 2012;75:269-74 pubmed publisher
  • immunohistochemistry; human
Wang C, Liau J, Lu Y, Chen J, Yao Y, Lien H. Differential expression of moesin in breast cancers and its implication in epithelial-mesenchymal transition. Histopathology. 2012;61:78-87 pubmed publisher
  • immunohistochemistry; human
Demirag F, Cakir E, Alpar S, Tastepe I, Kaya S. Expression of CD44 and MMP-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors. Turk Patoloji Derg. 2011;27:127-33 pubmed publisher
  • immunohistochemistry - paraffin section; human
Petrilli G, Lorenzi L, Paracchini R, Ubiali A, Schumacher R, Cabassa P, et al. Epstein-Barr virus-associated adrenal smooth muscle tumors and disseminated diffuse large B-cell lymphoma in a child with common variable immunodeficiency: a case report and review of the literature. Int J Surg Pathol. 2014;22:712-21 pubmed publisher
  • immunocytochemistry; human; tbl 1
Ingthorsson S, Halldorsson T, Sigurdsson V, Friðriksdottir A, Bodvarsdottir S, Steinarsdottir M, et al. Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary background. In Vitro Cell Dev Biol Anim. 2011;47:139-48 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 2, 3, 4
Baydar D, Kulac I, Gurel B, De Marzo A. A case of prostatic adenocarcinoma with aberrant p63 expression: presentation with detailed immunohistochemical study and FISH analysis. Int J Surg Pathol. 2011;19:131-6 pubmed publisher
  • immunohistochemistry; human; 1:50
Perrone F, Jocollè G, Pennati M, Deraco M, Baratti D, Brich S, et al. Receptor tyrosine kinase and downstream signalling analysis in diffuse malignant peritoneal mesothelioma. Eur J Cancer. 2010;46:2837-48 pubmed publisher
  • immunohistochemistry; human; 1:20
Kapucuoglu N, Percinel S, Ventura T, Lang R, Al Daraji W, Eusebi V. Dendritic cell sarcomas/tumours of the breast: report of two cases. Virchows Arch. 2009;454:333-9 pubmed publisher
  • immunohistochemistry; human; 1:20
Dogu G, Ozkan M, Ozturk F, Dikilitas M, Er O, Ozturk A. Triple-negative breast cancer: immunohistochemical correlation with basaloid markers and prognostic value of survivin. Med Oncol. 2010;27:34-9 pubmed publisher
  • immunohistochemistry; human
Fadare O, Mariappan M. Mucocele-like tumor and columnar cell hyperplasia of the breast occurring in a morphologic continuum. J Med Case Rep. 2008;2:138 pubmed publisher
  • immunohistochemistry; human
Fadare O, Wang S, Hileeto D. The expression of cytokeratin 5/6 in invasive lobular carcinoma of the breast: evidence of a basal-like subset?. Hum Pathol. 2008;39:331-6 pubmed publisher
  • immunohistochemistry; human
Liu H, Fan Q, Zhang Z, Li X, Yu H, Meng F. Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancers. Hum Pathol. 2008;39:167-74 pubmed
  • immunohistochemistry - paraffin section; human; 1:50; tbl 1
Blind C, Koepenik A, Pacyna Gengelbach M, Fernahl G, Deutschmann N, Dietel M, et al. Antigenicity testing by immunohistochemistry after tissue oxidation. J Clin Pathol. 2008;61:79-83 pubmed
  • immunohistochemistry; human
Demirag F, Unsal E, Tastepe I. Biphasic malignant mesothelioma cases with osseous differentiation and long survival: a review of the literature. Lung Cancer. 2007;57:233-6 pubmed
Parisi F, Muscatello L, Civita P, Lessi F, Menicagli M, Millanta F, et al. Pathological Features and Molecular Phenotype of MMTV Like-Positive Feline Mammary Carcinomas. Animals (Basel). 2021;11: pubmed publisher
Chuang H, Chang Y, Huang Y, Liao J, Kao P, Chen Y, et al. Establishment and Characterization of Feline Mammary Tumor Patient-Derived Xenograft Model. Animals (Basel). 2021;11: pubmed publisher
Blanchard A, Ma X, Wang N, Hombach Klonisch S, Penner C, Ozturk A, et al. Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies. Transl Oncol. 2019;12:561-575 pubmed publisher
Németh I, Tiszlavicz L. Biphenotypic surface epithelial cells in the gastrointestinal tube with mixed epithelial-myofibroblastic differentiation: a paradigm. Pathol Oncol Res. 2012;18:391-6 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Cytokeratin 5/6 Monoclonal Antibody (D5/16 B4)
Catalog # :
MA1-91106
Quantity :
250 uL
Price :
US 532.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:25-1:50
Species :
Human
Clone :
D5/16 B4
Isotype :
IgG1
Storage :
4 C
Description :
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Immunogen :
Cytokeratin 5 (Human).
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:25-1:50
Aliases :
2310016L08Rik; 3300001P10Rik; 58 kDa cytokeratin; 60-kDa keratin; AW146334; CK5; CK-5; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; Hom s 5; K5; K6A; K6a keratin; K6C; K6D; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; keratin-5; keratin-6A; Keratin-6-alpha; keratin-6C; Krt2-5; Krt2-6; Krt2-6a; Krt2-6c; krt5; KRT5A; Krt6; Krt6a; KRT6C; KRT6D; LOC683313; mK6[a]; MK6a; mK6-alpha; PC3; Sak57; similar to keratin complex 2, basic, gene 6a; Tfip8; tuftelin interacting protein 8; type-II keratin Kb12; type-II keratin Kb5; Type-II keratin Kb6
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA