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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
alpha-II Spectrin Monoclonal Antibody (D8B7)
catalog :
MA1-91103
quantity :
100 uL
price :
US 676.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D8B7
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:5000; fig 1
Chen S, Shi Q, Zheng S, Luo L, Yuan S, Wang X, et al. Role of ?-II-spectrin breakdown products in the prediction of the severity and clinical outcome of acute traumatic brain injury. Exp Ther Med. 2016;11:2049-2053 pubmed
product information
Product Type :
Antibody
Product Name :
alpha-II Spectrin Monoclonal Antibody (D8B7)
Catalog # :
MA1-91103
Quantity :
100 uL
Price :
US 676.00
Clonality :
Monoclonal
Host :
Mouse
Reactivity :
Human
Applications :
ELISA: 1:100,000-1:1,000,000, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Frozen): 1:50-1:100, Western Blot: 1:100-1:1,000
Species :
Human
Clone :
D8B7
Isotype :
IgG2b
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins. They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Immunogen :
Recombinant alpha II spectrin (non-erythroid spectrin or fodrin) SH3 domain (Human).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:100,000-1:1,000,000, Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Frozen): 1:50-1:100, Western Blot: 1:100-1:1,000
Aliases :
(ALPHA)II-SPECTRIN; 2610027H02Rik; A2a; a--fodrin; alpha; alpha II spectrin; alpha-fodrin; alpha-II spectrin; alpha-spectrin; alpha-spectrin 2; alpha-spectrin 2, brain; brain; brain alpha-spectrin; EIEE5; FLJ44613; Fodrin alpha chain; inhibitory protein factor; IPF; NEAS; noerythroid alpha-spectrin 2; Non erythrocytic spectrin alpha; non-erythrocytic 1 (alpha-fodrin); non-erythroid alpha chain; nonerythroid alpha-spectrin; nonerythroid alpha-spectrin 2; putative alpha-spectrin; SPECA; Spectrin; Spectrin alpha; spectrin alpha chain; Spectrin alpha chain brain; spectrin alpha chain, brain; spectrin alpha chain, non-erythrocytic 1; spectrin alpha, non-erythrocytic 1; spectrin, alpha, non-erythrocytic 1; spectrin, alpha, non-erythrocytic 1 (alpha-fodrin); spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; Spna2; Spna-2; Spta2; Sptan1
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA