SV40 T-Antigen Monoclonal Antibody (PAb416) | Invitrogen MA1-90661 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SV40 T-Antigen Monoclonal Antibody (PAb416)

catalog :

MA1-90661

quantity :

500 uL

price :

US 524.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PAb416

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 2

Reference
Bae D, Marino M, Iaffaldano B, Fenstermaker S, Afione S, Argaw T, et al. Design and Testing of Vector-Producing HEK293T Cells Bearing a Genomic Deletion of the SV40 T Antigen Coding Region. Mol Ther Methods Clin Dev. 2020;18:631-638 pubmed publisher
Tsai K, Courtney D, Cullen B. Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication. PLoS Pathog. 2018;14:e1006919 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SV40 T-Antigen Monoclonal Antibody (PAb416)

Catalog # :

MA1-90661

Quantity :

500 uL

Price :

US 524.00

Clonality :

Monoclonal

Purity :

Antigen affinity chromatography

Host :

Mouse

Reactivity :

Virus

Applications :

Immunocytochemistry: 1-5 ug/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: 1-5 ug/mL, Western Blot: 1-5 ug/mL

Species :

Virus

Clone :

PAb416

Isotype :

IgG2a

Storage :

4 C, do not freeze

Description :

The SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

Immunogen :

Full length protein (purified) (SV40).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-5 ug/mL, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: 1-5 ug/mL, Western Blot: 1-5 ug/mL

Aliases :

simian vacuolating virus 40; simian virus; Simian virus 40; SV40 T-antigen; sv40 virus large t antigen