Involucrin Monoclonal Antibody (SY8) | Invitrogen MA1-90573 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Involucrin Monoclonal Antibody (SY8)

catalog :

MA1-90573

quantity :

100 µg

price :

US 592

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SY8

reactivity :

gorilla , human, dogs, pigs

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Involucrin Monoclonal Antibody (SY8)

Catalog # :

MA1-90573

Quantity :

100 µg

Price :

US 592

Clonality :

Monoclonal

Purity :

Protein G

Host :

Mouse

Reactivity :

Avian, Canine, Human, Non-human primate, Porcine

Applications :

Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 0.75 µg/mL

Species :

Avian, Canine, Human, Non-human primate, Porcine

Clone :

SY8

Isotype :

IgG1

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures it is expressed by all cells that have left the basal layer. Involucrin expression is abnormal in squamous cell carcinomas and premalignant lesions and is reduced in severe dysplasias of the larynx and cervix. Its gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.

Immunogen :

Pure involucrin from human keratinocytes.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 0.75 µg/mL

Aliases :

1110019C06Rik; involucrin; IVL