GM-CSF Monoclonal Antibody (BVD2-21C11), Biotin | Invitrogen MA1-83531 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GM-CSF Monoclonal Antibody (BVD2-21C11), Biotin

catalog :

MA1-83531

quantity :

500µg

price :

US 610.00

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

BVD2-21C11

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

GM-CSF Monoclonal Antibody (BVD2-21C11), Biotin

Catalog # :

MA1-83531

Quantity :

500µg

Price :

US 610.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rat

Reactivity :

Human

Applications :

ELISA: Assay Dependent, Flow Cytometry: Assay Dependent

Species :

Human

Clone :

BVD2-21C11

Isotype :

IgG2a

Storage :

4°C or -20°C if preferred

Description :

GM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, and stimulates the development of granulocytes, macrophages, early megakaryocytes and eosinophil progenitor cells. The active form of the GM-CSF protein is found extracellularly as a homodimer and the GM-CSF gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q-syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The ability of recombinant GM-CSF to increase hematopoietic cell recovery has become a focus area in the therapeutic treatment of patients following bone marrow transplantation. Recent studies have investigated GM-CSF in inflammatory and autoimmune diseases such as arthritis, arthritis related interstitial lung disease, nephritis, and psoriasis. In the CNS, GM-CSF depletion or neutralization has been studied in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).

Immunogen :

Proprietary Immunogen.

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay Dependent, Flow Cytometry: Assay Dependent

Aliases :

Csfgm, Gm-CSf, MGC151255, MGC151257, MGI-IGM