CD68 Monoclonal Antibody (Ki-M7), FITC | Invitrogen MA1-82715 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD68 Monoclonal Antibody (Ki-M7), FITC

catalog :

MA1-82715

quantity :

100 Tests

price :

US 490.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

Ki-M7

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:200	Zhang M, He Y, Sun X, Li Q, Wang W, Zhao A, et al. A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients. J Ovarian Res. 2014;7:19 pubmed publisher
immunohistochemistry; human	Desdouits M, Cassar O, Maisonobe T, Desrames A, Aouba A, Hermine O, et al. HTLV-1-associated inflammatory myopathies: low proviral load and moderate inflammation in 13 patients from West Indies and West Africa. J Clin Virol. 2013;57:70-6 pubmed publisher
flow cytometry; human immunohistochemistry; human	Jensen A, Collins J, Shipman E, Wira C, Guyre P, Pioli P. A subset of human uterine endometrial macrophages is alternatively activated. Am J Reprod Immunol. 2012;68:374-86 pubmed publisher
immunohistochemistry - frozen section; human; 1:30; fig 1	Syrio N, Faria D, Gomez R, Gollob K, Dutra W, Souza P. IL-10 and IL-10 receptor overexpression in oral giant cell lesions. Med Oral Patol Oral Cir Bucal. 2011;16:e488-92 pubmed
flow cytometry; human	Esser J, Gehrmann U, D Alexandri F, Hidalgo Estévez A, Wheelock C, Scheynius A, et al. Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration. J Allergy Clin Immunol. 2010;126:1032-40, 1040.e1-4 pubmed publisher
	Zhu Q, Yuan J, He Y, Hu Y. The Effect of miR-520b on Macrophage Polarization and T Cell Immunity by Targeting PTEN in Breast Cancer. J Oncol. 2021;2021:5170496 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD68 Monoclonal Antibody (Ki-M7), FITC

Catalog # :

MA1-82715

Quantity :

100 Tests

Price :

US 490.00

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:100

Species :

Human

Clone :

Ki-M7

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

Immunogen :

Cell suspensions of human lymph node.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay-dependent, Immunocytochemistry: 1:100

Aliases :

CD68; CD68 antigen; CD68 molecule; GP110; Lamp4; macrophage antigen CD68; macrosialin; Scard1; scavenger receptor class D, member 1; similar to CD68 antigen

more info or order :

Invitrogen product webpage