product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD44v6 Monoclonal Antibody (VFF-7)
catalog :
MA1-82392
quantity :
100 ug
price :
US 636.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VFF-7
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; human; loading ...
Horvatinovich J, Grogan E, Norris M, Steinkasserer A, Lemos H, Mellor A, et al. Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes. J Immunol. 2017;198:2286-2301 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Ando K, Fujino N, Mitani K, Ota C, Okada Y, Kondo T, et al. Isolation of individual cellular components from lung tissues of patients with lymphangioleiomyomatosis. Am J Physiol Lung Cell Mol Physiol. 2016;310:L899-908 pubmed publisher
  • immunohistochemistry; human
Wang Y, Chen W, Huang Z, Yang Z, Zhang B, Wang J, et al. Expression of the membrane-cytoskeletal linker Ezrin in salivary gland adenoid cystic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112:96-104 pubmed publisher
  • flow cytometry; human; fig 4
Ikeda Y, Taveira DaSilva A, Pacheco Rodriguez G, Steagall W, El Chemaly S, Gochuico B, et al. Erythropoietin-driven proliferation of cells with mutations in the tumor suppressor gene TSC2. Am J Physiol Lung Cell Mol Physiol. 2011;300:L64-72 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:80; fig 2
Nasir A, Catalano E, Calafati S, Cantor A, Kaiser H, Coppola D. Role of p53, CD44V6 and CD57 in differentiating between benign and malignant follicular neoplasms of the thyroid. In Vivo. 2004;18:189-95 pubmed
  • immunohistochemistry - paraffin section; human; fig 1
Ylagan L, Scholes J, Demopoulos R. Cd44: a marker of squamous differentiation in adenosquamous neoplasms. Arch Pathol Lab Med. 2000;124:212-5 pubmed
Zuo Z, Tang Y, Bi C, Zhang W, Zhao S, Wang X, et al. Extraosseous (extramedullary) plasmacytomas: a clinicopathologic and immunophenotypic study of 32 Chinese cases. Diagn Pathol. 2011;6:123 pubmed publisher
product information
Product Type :
Antibody
Product Name :
CD44v6 Monoclonal Antibody (VFF-7)
Catalog # :
MA1-82392
Quantity :
100 ug
Price :
US 636.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 1:50-1:200, Immunohistochemistry (Frozen): 1:400-1:500, Immunohistochemistry (Paraffin): 1:200, Western Blot: Assay-dependent
Species :
Human
Clone :
VFF-7
Isotype :
IgG1
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
CD44 cell surface antigen is a 100kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
Immunogen :
Fusion protein corresponding to the variable domains (v3 to v10) of human CD44.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:50-1:200, Immunohistochemistry (Frozen): 1:400-1:500, Immunohistochemistry (Paraffin): 1:200, Western Blot: Assay-dependent
Aliases :
AL133330.1; AU023126; AW121933; AW146109; CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44 splice variant; CD44 V6; CD44 var; CD44 variant; CD44v6; CD44var (v6); CDW44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMRIII; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCELL; hematopoietic cell E- and L-selectin ligand; heparan sulfate proteoglycan; HERMES; Hermes antigen; homing function and Indian blood group system; HUTCHI; HUTCH-I; Hyaluronate receptor; IN; LHR; Ly-24; Lymphocyte antigen 24; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH-I; PGP I; Pgp1; Pgp-1; PGP-I; Phagocytic glycoprotein 1; phagocytic glycoprotein I; soluble CD44
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA